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NCT03359226 · ClinicalTrials.gov registry record · NA
Transcutaneous Submandibular Gland Biopsy: Feasibility of Repeat Biopsy as a Progression Marker for Parkinson's Disease
A NA study, sponsored by Mayo Clinic.
- Completed
- Registry status
- NA
- Development phase
- 7
- Enrollment target
NCT03359226: Completed NA study, sponsored by Mayo Clinic.
NCT03359226 is a NA study that has completed, run by Mayo Clinic. The registered enrollment target is 7 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03359226, a NA study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- NA
- Development phase
- 7 participants
- Enrollment target
Study Summary
The purpose of this study is to perform biopsies of one of the glands that make saliva. The biopsied tissue will then be analyzed to see if it has changes that occur in Parkinson's disease. This study will determine whether it is possible to do a second biopsy a few years after a previous biopsy and determine whether there are changes in the biopsy that would allow for analysis of disease progression.
Primary Outcome
The biopsied submandibular gland tissue will be stained with an antibody for alpha-synuclein. The pathologist will review the slides and determine the number that show positive staining for neuronal elements. He will compare the number of positive slides between the right and left submandibular glands to see if they are similar.
Interventions
- PROCEDURE Submandibular gland biopsy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2017-11-21 |
| Est. Completion | 2018-05-31 |
| Phase | NA |
What the finished NCT03359226 record still lists
NCT03359226 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which Submandibular gland biopsy is the first listed.
NCT03359226 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03359226 about?
NCT03359226 is a clinical study titled "Transcutaneous Submandibular Gland Biopsy: Feasibility of Repeat Biopsy as a Progression Marker for Parkinson's Disease". The purpose of this study is to perform biopsies of one of the glands that make saliva. The biopsied tissue will then be analyzed to see if it has changes that occur in Parkinson's disease. This study will determine whether it is possible to do a second biopsy a few years after a previous biopsy and...
What is the current status of trial NCT03359226?
This trial is currently completed. It is a NA study. The enrollment target is 7 participants. The study started on 2017-11-21. Estimated completion is 2018-05-31.
What interventions are being tested in trial NCT03359226?
The interventions under investigation include: Submandibular gland biopsy (PROCEDURE).
Who is sponsoring clinical trial NCT03359226?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03359226's enrollment target sits among peer trials
7 1982nd of 2000 higher than 18 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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