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NCT04286529 · ClinicalTrials.gov registry record · Phase 1
Effect of 1,25-dihydroxyvitamin D3, Treatment on Insulin Secretion and Muscle Strength in Pre-diabetic Persons
A Phase 1 study, sponsored by Mayo Clinic.
- Terminated
- Registry status
- Phase 1
- Development phase
- 17
- Enrollment target
NCT04286529: Clinical Trial Phase 1 study, sponsored by Mayo Clinic.
NCT04286529 is a Phase 1 study that was terminated before completion, run by Mayo Clinic. The registered enrollment target is 17 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (72% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04286529, a Phase 1 study, was terminated before completion, sponsored by Mayo Clinic.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 17 participants
- Enrollment target
Study Summary
The purpose of this research is to study the effects of 1,25(OH)2 D3 (a prescription form of active Vitamin D) on muscle strength and insulin secretion by the pancreas and glucose utilization by skeletal muscle.
Primary Outcome
Blood will be obtained to measure glucose after a glucose tolerance test. The glucose tolerance test involves an overnight fast and then participants will ingest a drink containing 75 grams of glucose with blood obtained over a 120 minute period.
Interventions
- DRUG Oral Placebo
- DRUG Calcitriol capsules
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 17 participants |
| Start Date | 2020-10-01 |
| Est. Completion | 2021-05-28 |
| Phase | Phase 1 |
Why NCT04286529 stopped before completion
NCT04286529 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 17 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (72% lower).
The record links to 0 conditions, and to 2 interventions - of which Oral Placebo is the first listed.
NCT04286529 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04286529 about?
NCT04286529 is a clinical study titled "Effect of 1,25-dihydroxyvitamin D3, Treatment on Insulin Secretion and Muscle Strength in Pre-diabetic Persons". The purpose of this research is to study the effects of 1,25(OH)2 D3 (a prescription form of active Vitamin D) on muscle strength and insulin secretion by the pancreas and glucose utilization by skeletal muscle.
What is the current status of trial NCT04286529?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 17 participants. The study started on 2020-10-01. Estimated completion is 2021-05-28.
What interventions are being tested in trial NCT04286529?
The interventions under investigation include: Oral Placebo (DRUG), Calcitriol capsules (DRUG).
Who is sponsoring clinical trial NCT04286529?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04286529's enrollment target sits among peer trials
17 1785th of 2000 higher than 215 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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