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NCT05445427 · ClinicalTrials.gov registry record · NA

Vagal Nerve Stimulation for Post COVID Fatigue

A NA study of Fatigue and Headache, sponsored by Mayo Clinic.

Completed
Registry status
NA
Development phase
18
Enrollment target
1
Study location

NCT05445427: Completed NA study of Fatigue and Headache, sponsored by Mayo Clinic.

NCT05445427 is a NA study of Fatigue and Headache that has completed, run by Mayo Clinic. The registered enrollment target is 18 participants, below the 218-participant average among 109 other Fatigue trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05445427, a NA study of Fatigue and Headache, has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
NA
Development phase
18 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to evaluate the impact of vagal nerve stimulation on patients with post COVID syndrome who have fatigue and headache.

Primary Outcome

Measurement is the change in scoring determined through patients' self-reported Post-COVID Functional Status Score survey, which assesses COVID-19 symptom impact on a grading scale of 0 = no limitations to 4 = severe limitations. Thus, higher scores are a worse outcome, and a change indicating an increase is a worsening of functional status.

Interventions

  • DEVICE vagal nerve stimulator

Study Locations (1)

Minnesota

  • Mayo Clinic in Rochester - Rochester

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2022-12-21
Est. Completion 2024-03-28
Phase NA
Mayo Clinic

2,844 total trials

What the finished NCT05445427 record still lists

NCT05445427 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 218-participant average among 109 other Fatigue trials with a reported enrollment target (92% lower).

The record links to 3 conditions, with Fatigue appearing as the primary indexed condition, and to 1 intervention - of which vagal nerve stimulator is the first listed.

NCT05445427 reports a single indexed study location in Minnesota.

Frequently Asked Questions

What is clinical trial NCT05445427 about?

NCT05445427 is a clinical study titled "Vagal Nerve Stimulation for Post COVID Fatigue". The purpose of this study is to evaluate the impact of vagal nerve stimulation on patients with post COVID syndrome who have fatigue and headache.

What is the current status of trial NCT05445427?

This trial is currently completed. It is a NA study. The enrollment target is 18 participants. The study started on 2022-12-21. Estimated completion is 2024-03-28.

What conditions does trial NCT05445427 study?

This clinical trial studies the following conditions: Fatigue, Headache, Post COVID Syndrome.

What interventions are being tested in trial NCT05445427?

The interventions under investigation include: vagal nerve stimulator (DEVICE).

Who is sponsoring clinical trial NCT05445427?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05445427 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Fatigue

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05445427's enrollment target sits among peer trials

18 97th of 109 higher than 12 of 109 other Fatigue trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Fatigue trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05445427, the US trial registry maintained by the National Library of Medicine. NCT05445427 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.