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NCT05514119 · ClinicalTrials.gov registry record · Phase 2

A Study to Assess the Role of Fenofibrate in Preventing Ischemic Cholangiopathy After Liver Transplantation

A Phase 2 study, sponsored by Mayo Clinic.

Terminated
Registry status
Phase 2
Development phase
6
Enrollment target

NCT05514119: Clinical Trial Phase 2 study, sponsored by Mayo Clinic.

NCT05514119 is a Phase 2 study that was terminated before completion, run by Mayo Clinic. The registered enrollment target is 6 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT05514119, a Phase 2 study, was terminated before completion, sponsored by Mayo Clinic.

TERMINATED
Registry status
Phase 2
Development phase
6 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the safety and effectiveness of a once-daily medication, fenofibrate (Lofibra), to prevent ischemic cholangiography (IC) in persons who were transplanted with livers donated after circulatory death (DCD).

Primary Outcome

Proportion of subjects to discontinue fenofibrate due to adverse events

Interventions

  • DRUG Fenofibrate

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2022-08-17
Est. Completion 2024-12-01
Phase Phase 2
Mayo Clinic

2,844 total trials

Why NCT05514119 stopped before completion

NCT05514119 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 1 intervention - of which Fenofibrate is the first listed.

NCT05514119 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05514119 about?

NCT05514119 is a clinical study titled "A Study to Assess the Role of Fenofibrate in Preventing Ischemic Cholangiopathy After Liver Transplantation". The purpose of this study is to evaluate the safety and effectiveness of a once-daily medication, fenofibrate (Lofibra), to prevent ischemic cholangiography (IC) in persons who were transplanted with livers donated after circulatory death (DCD).

What is the current status of trial NCT05514119?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 6 participants. The study started on 2022-08-17. Estimated completion is 2024-12-01.

What interventions are being tested in trial NCT05514119?

The interventions under investigation include: Fenofibrate (DRUG).

Who is sponsoring clinical trial NCT05514119?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05514119's enrollment target sits among peer trials

6 1996th of 2000 higher than 1 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05514119, the US trial registry maintained by the National Library of Medicine. NCT05514119 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.