Massachusetts General Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).

2,032 total trials 336 currently recruiting 1284 completed early-phase tilt top decile by trial count

Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.

Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.

Top-decile sponsor footprint

Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,032 total, page 33 of 41

COMPLETED NA

Using Video Images to Improve Advance Care Planning in Patients With Cancer

NCT00970125

COMPLETED Phase 4

Duloxetine for Menopausal Depression

NCT01117857

COMPLETED NA

Proton Beam Irradiation for the Treatment of Unresectable Hepatocellular Cancer and Cholangiocarcinoma

NCT00976898

COMPLETED NA

Evaluate the Use of Optical Frequency Domain Imaging (OFDI) for Celiac Disease in Children, Adolescents and Young Adults

NCT01439035

COMPLETED Phase 1

A Pilot Study of a Dendritic Cell Vaccine in HIV-1 Infected Subjects

NCT00833781

COMPLETED Phase 2

Treatment of Older Adults With Acute Lymphoblastic Leukemia

NCT00973752

COMPLETED NA

D-cycloserine Augmentation of Cognitive Remediation in Schizophrenia

NCT00963924

TERMINATED Phase 1

Vorinostat With XRT and 5-FU for Locally Advanced Adenocarcinoma of the Pancreas

NCT00948688

TERMINATED NA

Early Detection and Intervention for Mild and Moderate Lymphedema in Patients Treated for Breast Cancer

NCT00959985

COMPLETED NA

Optical Frequency Domain Imaging for Assessing Colonic Polyps

NCT01439087

COMPLETED Phase 2

High Dose Rituximab for Initial Treatment of Indolent B-Cell Lymphomas

NCT00895661

COMPLETED NA

Direct to Smoker Outreach in a Health Care Setting

NCT01321944

COMPLETED Phase 4

Omega-3 Fatty Acids (Lovaza) for Second Generation Antipsychotic-Associated Hypertriglyceridemia

NCT00833976

COMPLETED Phase 1

Kisspeptin Administration in the Adult

NCT00914823

COMPLETED NA

fMRI Study of Expectancy on Acupuncture Treatment Outcomes in Knee OA

NCT01040754

COMPLETED Phase 2

Denosumab, Teriparatide or Both for the Treatment of Postmenopausal Osteoporosis

NCT00926380

COMPLETED NA

Cognitive-Behavioral Therapy for Pediatric Body Dysmorphic Disorder

NCT01002326

COMPLETED Phase 1

A Pilot Study of the Grapefruit Flavonoid Naringenin for HCV Infection

NCT01091077

COMPLETED Phase 2

Premanifest Huntington's Disease: Creatine Safety & Tolerability Extension Study

NCT01411150

COMPLETED NA

Different Vitamin D Preparations & FGF23 in Humans

NCT00957879

COMPLETED Phase 3

Fat Mediated Modulation of Reproductive and Endocrine Function in Young Athletes

NCT00946192

COMPLETED NA

Two Approaches to Routine HIV Testing in a Hospital Emergency Department

NCT01258582

COMPLETED Phase 2

Everolimus Plus Rituximab for Relapsed/Refractory Diffuse Large B Cell Lymphoma

NCT00869999

COMPLETED Phase 2

Panitumumab in Cetuximab Refractory KRAS Wild-Type Colorectal Cancer

NCT00842257

COMPLETED Phase 1

Study of Islet Transplantation in Type 1 Diabetic Kidney Transplant Recipients

NCT00888628

COMPLETED NA

Effects of Relaxation Response Mind-body Intervention in Patients With IBS and IBD

NCT02136745

COMPLETED Phase 3

Safety and Efficacy Of Drospirenone and Ethinyl Estradiol vs Placebo in the Treatment of Truncal Acne

NCT00722761

COMPLETED

Metabolome and Microbiomic in Fecal Samples

NCT00938028

COMPLETED NA

Relaxation Response Training to Treat Hypertension

NCT01263743

COMPLETED NA

Using Videos in Advance Care Planning for Patients With Advanced Cancer

NCT01241929

COMPLETED NA

Effect of Inpatient Diabetes Management on Outpatient Glycemic Control

NCT00869362

COMPLETED Phase 1

Topical Imiquimod 5% Cream for Treatment of Cutaneous Neurofibromas in Adults With Neurofibromatosis 1

NCT00865644

COMPLETED

Validation of a Questionnaire to Identify Signs and Symptoms of Nephrogenic Systemic Fibrosis

NCT00869479

COMPLETED NA

Efficacy of Structured Insulin Order

NCT01130558

COMPLETED NA

Optical Frequency Domain Imaging (OFDI) for Biliary Stricture Imaging

NCT01439620

COMPLETED NA

Effect of Short Term Growth Hormone Releasing Hormone in Healthy Men

NCT00850564

COMPLETED

Dual-Source Computed Tomography to Improve Prediction of Response to Cardiac Resynchronization Therapy

NCT01097733

COMPLETED Phase 1

PCI-24781 in Combination With Doxorubicin to Treat Sarcoma

NCT01027910

COMPLETED NA

Diabetes Connect: Patients and Providers Use of a Secure Website for Blood Glucose Monitoring in Type-2 Diabetes

NCT00812539

COMPLETED Phase 2

Safety and Efficacy Study of Clindamycin Phosphate 1.2% and Tretinoin 0.025% Gel to Treat Rosacea

NCT00823901

COMPLETED NA

Effects of Short-term Growth Hormone in HIV-infected Patients

NCT00795210

COMPLETED

Correlation Between Skin Carotenoid Levels and Previous History of Skin Cancer

NCT00836342

COMPLETED NA

Effect of Intranasal Neuropeptide on Emotion Perception in Trait Anxiety

NCT01551303

COMPLETED Phase 1

EASI Access II --- Follow-up Study to the EASI Access Trial

NCT00740727

COMPLETED

Healthy Lifestyle in Adults With Attention Deficit Hyperactivity Disorder

NCT00879320

COMPLETED NA

Does Mindfulness Training Change the Processing of Social Threat?

NCT00992875

COMPLETED Phase 1

Treatment of Recurrent Primary or Secondary Central Nervous System (CNS) Lymphoma With ALIMTA (Pemetrexed)

NCT00916630

COMPLETED NA

Effectiveness of Telepsychiatry-based Culturally Sensitive Collaborative Treatment of Depressed Chinese Americans

NCT00854542

COMPLETED Phase 1

Photobiomodulation to Alter Cerebral Blood Flow and to Affect the Emotional Status of Patients With Major Depression

NCT00961454

COMPLETED Phase 4

Escitalopram (Lexapro) for the Treatment of Postpartum Depression

NCT00833469

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Phase Distribution

PhaseTrial count
Phase 1 226
Phase 2 289
Phase 3 58
Phase 4 182

What is open in the Massachusetts General Hospital pipeline

336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).

Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).

Top condition: Depression (29 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.