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NCT01097733 · ClinicalTrials.gov registry record

Dual-Source Computed Tomography to Improve Prediction of Response to Cardiac Resynchronization Therapy

A clinical trial of Heart Failure - NYHA II - IV and Wide QRS Complex, sponsored by Massachusetts General Hospital.

Completed
Registry status
38
Enrollment target
1
Study location

NCT01097733 is a study of Heart Failure - NYHA II - IV and Wide QRS Complex that has completed, run by Massachusetts General Hospital. The registered enrollment target is 38 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT01097733, a study of Heart Failure - NYHA II - IV and Wide QRS Complex, has completed, sponsored by Massachusetts General Hospital.

COMPLETED
Registry status
38 participants
Enrollment target
1
Study location

Study Summary

Cardiac Resynchronization Therapy (CRT) is a widely accepted treatment that has led to improved clinical outcomes for patients with refractory congestive heart failure (CHF), systolic dysfunction, and wide QRS duration. However, it requires implantation of an expensive device ($30,000) and about 1/3 of patients do not have clinical improvement. Inadequate amounts of LV dyssynchrony or suboptimal lead placement may limit clinical response. Dual-Source computed tomography (DSCT) allows for subtle detection during myocardial contraction for assessing LV dyssynchrony, and can also assess coronary venous anatomy and scar burden. Thus DSCT may be the ideal noninvasive modality to predict response to CRT.

Interventions

  • OTHER Randomization of Pre-knowledge of CT coronary venography

Study Locations (1)

Massachusetts

  • Massachusetts General Hospital - Boston

Trial Details

FieldValue
Enrollment Target 38 participants
Start Date 2009-02
Est. Completion 2012-01

Sponsor

Massachusetts General Hospital

2,032 total trials

What the Registry Record Tells You About NCT01097733

The ClinicalTrials.gov registry entry for NCT01097733 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 38 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Heart Failure - NYHA II - IV appearing as the primary indexed condition, and to 1 intervention - of which Randomization of Pre-knowledge of CT coronary venography is the first listed.

NCT01097733 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT01097733 about?

NCT01097733 is a clinical study titled "Dual-Source Computed Tomography to Improve Prediction of Response to Cardiac Resynchronization Therapy". Cardiac Resynchronization Therapy (CRT) is a widely accepted treatment that has led to improved clinical outcomes for patients with refractory congestive heart failure (CHF), systolic dysfunction, and wide QRS duration. However, it requires implantation of an expensive device ($30,000) and about 1/3...

What is the current status of trial NCT01097733?

This trial is currently completed. The enrollment target is 38 participants. The study started on 2009-02. Estimated completion is 2012-01.

What conditions does trial NCT01097733 study?

This clinical trial studies the following conditions: Heart Failure - NYHA II - IV, Wide QRS Complex.

What interventions are being tested in trial NCT01097733?

The interventions under investigation include: Randomization of Pre-knowledge of CT coronary venography (OTHER).

Who is sponsoring clinical trial NCT01097733?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01097733 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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