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NCT01097733 · ClinicalTrials.gov registry record
Dual-Source Computed Tomography to Improve Prediction of Response to Cardiac Resynchronization Therapy
A clinical trial of Heart Failure - NYHA II - IV and Wide QRS Complex, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- 38
- Enrollment target
- 1
- Study location
NCT01097733: Completed study of Heart Failure - NYHA II - IV and Wide QRS Complex, sponsored by Massachusetts General Hospital.
NCT01097733 is a study of Heart Failure - NYHA II - IV and Wide QRS Complex that has completed, run by Massachusetts General Hospital. The registered enrollment target is 38 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01097733, a study of Heart Failure - NYHA II - IV and Wide QRS Complex, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- 38 participants
- Enrollment target
- 1
- Study location
Study Summary
Cardiac Resynchronization Therapy (CRT) is a widely accepted treatment that has led to improved clinical outcomes for patients with refractory congestive heart failure (CHF), systolic dysfunction, and wide QRS duration. However, it requires implantation of an expensive device ($30,000) and about 1/3 of patients do not have clinical improvement. Inadequate amounts of LV dyssynchrony or suboptimal lead placement may limit clinical response. Dual-Source computed tomography (DSCT) allows for subtle detection during myocardial contraction for assessing LV dyssynchrony, and can also assess coronary venous anatomy and scar burden. Thus DSCT may be the ideal noninvasive modality to predict response to CRT.
Primary Outcome
The clinical response to CRT will be adjudicated by two experienced cardiologists taking into account left ventricular ejection fraction, NYHA functional class, and patient global assessment score.
Conditions Studied
Interventions
- OTHER Randomization of Pre-knowledge of CT coronary venography
Study Locations (1)
Massachusetts
- Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 38 participants |
| Start Date | 2009-02 |
| Est. Completion | 2012-01 |
What the finished NCT01097733 record still lists
NCT01097733 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 38 participants, a relatively small participant target.
The record links to 2 conditions, with Heart Failure - NYHA II - IV appearing as the primary indexed condition, and to 1 intervention - of which Randomization of Pre-knowledge of CT coronary venography is the first listed.
NCT01097733 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT01097733 about?
NCT01097733 is a clinical study titled "Dual-Source Computed Tomography to Improve Prediction of Response to Cardiac Resynchronization Therapy". Cardiac Resynchronization Therapy (CRT) is a widely accepted treatment that has led to improved clinical outcomes for patients with refractory congestive heart failure (CHF), systolic dysfunction, and wide QRS duration. However, it requires implantation of an expensive device ($30,000) and about 1/3...
What is the current status of trial NCT01097733?
This trial is currently completed. The enrollment target is 38 participants. The study started on 2009-02. Estimated completion is 2012-01.
What conditions does trial NCT01097733 study?
This clinical trial studies the following conditions: Heart Failure - NYHA II - IV, Wide QRS Complex.
What interventions are being tested in trial NCT01097733?
The interventions under investigation include: Randomization of Pre-knowledge of CT coronary venography (OTHER).
Who is sponsoring clinical trial NCT01097733?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01097733 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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