Massachusetts General Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,742 sponsors by registered trial count).
Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.
Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.
Top-decile sponsor footprint
Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
1,284 of 1,487 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
2,032 total, page 32 of 41
Effect of Varying Testosterone Levels on Insulin Sensitivity in Men With Idiopathic Hypogonadotropic Hypogonadism (IHH)
NCT03118479
Proton Beam Radiotherapy for Medulloblastoma and Pineoblastoma
NCT01063114
PF-00299804 in Adult Patients With Relapsed/Recurrent Glioblastoma
NCT01112527
Neuroimaging Studies of the Treatment of Bipolar Depression With Citalopram
NCT01639482
Magnetic Resonance Spectroscopic and Diffusion Tensor Imaging of Adolescents with Autism Spectrum Disorders
NCT01361503
Training in the Workplace
NCT01113944
Premanifest Huntington's Disease Extension Study II: Creatine Safety & Tolerability
NCT01411163
Hormonal Factors in the Treatment of Anorexia Nervosa
NCT01121211
A Study to Assess the Role of a Gluten Free-dairy Free (GFCF) Diet in the Dietary Management of Autism Associated Gastrointestinal Disorders
NCT01116388
Multicenter Study to Rule Out Myocardial Infarction by Cardiac Computed Tomography
NCT01084239
A Study of the Use of IV Scopolamine to Augment the Efficacy of Electroconvulsive Therapy (ECT)
NCT01312844
Mind-body Interventions in Cardiac Patients
NCT01270568
Metabolic Screening in Patients With Donnai-Barrow Syndrome
NCT01509287
Autism Spectrum Disorders (ASD) Driving Study
NCT01263756
HIV Fat Redistribution and the Evaluation of Brown Fat
NCT01098045
Computerized Information-Processing Bias Retraining in Depressed Adolescents
NCT01147913
Effectiveness of Pedialink CEASE Module
NCT01087177
Effect of Recombinant Human Growth Hormone (rhGH) on Abdominal Fat and Cardiovascular Risk in Obese Girls
NCT01169103
Intensity Modulated Radiation Therapy (IMRT) for Patients With Rectal Cancer
NCT01148056
Indocyanine Green Fluorescent Molecular Imaging of the Gastrointestinal Tract
NCT01112514
Sonoelastography: Ultrasound Method to Measure Liver Fibrosis
NCT01747772
Biopsies of Cancer Patients for Tumor Molecular Characterization
NCT01061944
Improving Empathy and Relational Skills
NCT01304030
Diagnostic Accuracy of Shear-Wave Elastography for the Preoperative Risk Stratification of Follicular Lesions of the Thyroid
NCT03106337
Evaluating the Effect of Acupuncture on Pain Relief Using Quantitative Sensory Testing (QST)
NCT01094782
An Acupuncture Functional Magnetic Resonance Imaging (fMRI) Study on Chronic Pain: Response Reliability and Dose Effect
NCT01079390
A Study of Memantine Hydrochloride (Namenda®) for Cognitive and Behavioral Impairment in Adults With Autism Spectrum Disorders
NCT01333865
Mindfulness-Based Cognitive Behavior Therapy for Bipolar Disorder
NCT01126827
Addressing Psychosocial Needs and HIV Risk in Indian MSM
NCT01266122
Safety of Lactobacillus Rhamnosus GG ATCC 53103 (LGG) in Healthy Volunteers
NCT00934453
Nutrition Intervention for the Promotion of Healthy Weight Gain During Pregnancy
NCT01056406
Culturally-focused Consultation for Asian Americans and Latino Americans
NCT01239407
Subcutaneous Omalizumab for Treatment of Chronic Rhinosinusitis With Nasal Polyposis
NCT01066104
Role of Beta-Endorphin in Cancer Therapy Fatigue
NCT01113905
A Pilot Trial of Sonoelastography for Planning Tumor-targeted Prostate Biopsy
NCT01748890
Impact of Hot Flashes on Sleep and Mood Disturbance
NCT01116401
Aging and Estrogen on Cortical Function
NCT01268046
DIVINE: Dialysis Infection and Vitamin D In New England
NCT00892099
Bevacizumab for Treatment of Recurrent Respiratory Papillomatosis (RRP)
NCT01020747
Orthopaedic Hand Service Data Repository
NCT01393262
Bariatric Surgery and Skeletal Health
NCT01098942
Health Management Training to Enhance Influenza Vaccine Immunogenicity
NCT01256515
Omega-3 Fatty Acids Monotherapy in Children and Adolescents With Autism Spectrum Disorders
NCT01248130
High Fat/High Calorie Trial in Amyotrophic Lateral Sclerosis
NCT00983983
Skills Training for Adolescents With ADHD
NCT01019252
Neurobehavioral Functioning in Pediatric Brain Tumor Patients After Proton Beam Radiation Treatment
NCT01180881
Diagnostic Utility of Attention Deficit Hyperactivity Disorder (ADHD) by Brain Activity Flow Patterns Analysis Using Evoked Response Potentials
NCT01063153
Statin Therapy to Improve Atherosclerosis in HIV Patients
NCT00965185
Functional MRI of Relaxation Response Training in Adults With Attention-Deficit/Hyperactivity Disorder
NCT01404273
Creatine Safety, Tolerability, & Efficacy in Huntington's Disease (CREST-E)
NCT00712426
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 226 |
| Phase 2 | 289 |
| Phase 3 | 58 |
| Phase 4 | 182 |
Therapeutic Areas
What is open in the Massachusetts General Hospital pipeline
336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).
Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).
Top condition: Depression (29 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Massachusetts General Hospital: open-pipeline peers nationwide
Peers matched on 2,032 registered trials and 17% open enrollment, not the therapeutic-area sidebar.
Massachusetts General Hospital sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 2,032 trials (± recruiting share)
- National Institute of Allergy and Infectious Diseases (NIAID) · 2,006 trials · 8% recruiting
- Memorial Sloan Kettering Cancer Center · 1,884 trials · 17% recruiting
- Pfizer · 1,845 trials · 6% recruiting
- Stanford University · 1,744 trials · 15% recruiting
Sponsors near 17% open enrollment (± trial volume)
- Rush University Medical Center · 17% recruiting · 320 trials
- OHSU Knight Cancer Institute · 17% recruiting · 211 trials
- Adagene · 17% recruiting · 6 trials
- Agendia · 17% recruiting · 6 trials
Related
What to do with this Massachusetts General Hospital page
2,032 registered trials is a research-attention snapshot, not an endorsement of Massachusetts General Hospital or any single study.
- 336 of Massachusetts General Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Depression is the condition Massachusetts General Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Depression trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Massachusetts General Hospital pipeline card: 2,032 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.