Massachusetts General Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).

2,032 total trials 336 currently recruiting 1284 completed early-phase tilt top decile by trial count

Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.

Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.

Top-decile sponsor footprint

Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,032 total, page 32 of 41

TERMINATED Phase 1

Effect of Varying Testosterone Levels on Insulin Sensitivity in Men With Idiopathic Hypogonadotropic Hypogonadism (IHH)

NCT03118479

COMPLETED NA

Proton Beam Radiotherapy for Medulloblastoma and Pineoblastoma

NCT01063114

COMPLETED Phase 2

PF-00299804 in Adult Patients With Relapsed/Recurrent Glioblastoma

NCT01112527

COMPLETED

Neuroimaging Studies of the Treatment of Bipolar Depression With Citalopram

NCT01639482

COMPLETED

Magnetic Resonance Spectroscopic and Diffusion Tensor Imaging of Adolescents with Autism Spectrum Disorders

NCT01361503

COMPLETED NA

Training in the Workplace

NCT01113944

COMPLETED Phase 2

Premanifest Huntington's Disease Extension Study II: Creatine Safety & Tolerability

NCT01411163

COMPLETED Phase 2

Hormonal Factors in the Treatment of Anorexia Nervosa

NCT01121211

COMPLETED NA

A Study to Assess the Role of a Gluten Free-dairy Free (GFCF) Diet in the Dietary Management of Autism Associated Gastrointestinal Disorders

NCT01116388

COMPLETED Phase 3

Multicenter Study to Rule Out Myocardial Infarction by Cardiac Computed Tomography

NCT01084239

TERMINATED Phase 2

A Study of the Use of IV Scopolamine to Augment the Efficacy of Electroconvulsive Therapy (ECT)

NCT01312844

COMPLETED NA

Mind-body Interventions in Cardiac Patients

NCT01270568

COMPLETED

Metabolic Screening in Patients With Donnai-Barrow Syndrome

NCT01509287

COMPLETED

Autism Spectrum Disorders (ASD) Driving Study

NCT01263756

COMPLETED

HIV Fat Redistribution and the Evaluation of Brown Fat

NCT01098045

COMPLETED Phase 2

Computerized Information-Processing Bias Retraining in Depressed Adolescents

NCT01147913

COMPLETED NA

Effectiveness of Pedialink CEASE Module

NCT01087177

COMPLETED Phase 2

Effect of Recombinant Human Growth Hormone (rhGH) on Abdominal Fat and Cardiovascular Risk in Obese Girls

NCT01169103

TERMINATED NA

Intensity Modulated Radiation Therapy (IMRT) for Patients With Rectal Cancer

NCT01148056

COMPLETED NA

Indocyanine Green Fluorescent Molecular Imaging of the Gastrointestinal Tract

NCT01112514

COMPLETED NA

Sonoelastography: Ultrasound Method to Measure Liver Fibrosis

NCT01747772

COMPLETED

Biopsies of Cancer Patients for Tumor Molecular Characterization

NCT01061944

COMPLETED NA

Improving Empathy and Relational Skills

NCT01304030

COMPLETED NA

Diagnostic Accuracy of Shear-Wave Elastography for the Preoperative Risk Stratification of Follicular Lesions of the Thyroid

NCT03106337

COMPLETED NA

Evaluating the Effect of Acupuncture on Pain Relief Using Quantitative Sensory Testing (QST)

NCT01094782

COMPLETED NA

An Acupuncture Functional Magnetic Resonance Imaging (fMRI) Study on Chronic Pain: Response Reliability and Dose Effect

NCT01079390

COMPLETED Phase 4

A Study of Memantine Hydrochloride (Namenda®) for Cognitive and Behavioral Impairment in Adults With Autism Spectrum Disorders

NCT01333865

COMPLETED NA

Mindfulness-Based Cognitive Behavior Therapy for Bipolar Disorder

NCT01126827

COMPLETED NA

Addressing Psychosocial Needs and HIV Risk in Indian MSM

NCT01266122

COMPLETED Phase 1

Safety of Lactobacillus Rhamnosus GG ATCC 53103 (LGG) in Healthy Volunteers

NCT00934453

COMPLETED NA

Nutrition Intervention for the Promotion of Healthy Weight Gain During Pregnancy

NCT01056406

COMPLETED NA

Culturally-focused Consultation for Asian Americans and Latino Americans

NCT01239407

COMPLETED Phase 2

Subcutaneous Omalizumab for Treatment of Chronic Rhinosinusitis With Nasal Polyposis

NCT01066104

TERMINATED

Role of Beta-Endorphin in Cancer Therapy Fatigue

NCT01113905

TERMINATED NA

A Pilot Trial of Sonoelastography for Planning Tumor-targeted Prostate Biopsy

NCT01748890

COMPLETED Phase 4

Impact of Hot Flashes on Sleep and Mood Disturbance

NCT01116401

COMPLETED Phase 1

Aging and Estrogen on Cortical Function

NCT01268046

COMPLETED NA

DIVINE: Dialysis Infection and Vitamin D In New England

NCT00892099

COMPLETED Phase 1

Bevacizumab for Treatment of Recurrent Respiratory Papillomatosis (RRP)

NCT01020747

COMPLETED

Orthopaedic Hand Service Data Repository

NCT01393262

COMPLETED

Bariatric Surgery and Skeletal Health

NCT01098942

COMPLETED NA

Health Management Training to Enhance Influenza Vaccine Immunogenicity

NCT01256515

TERMINATED Phase 2

Omega-3 Fatty Acids Monotherapy in Children and Adolescents With Autism Spectrum Disorders

NCT01248130

COMPLETED Phase 2

High Fat/High Calorie Trial in Amyotrophic Lateral Sclerosis

NCT00983983

COMPLETED NA

Skills Training for Adolescents With ADHD

NCT01019252

COMPLETED

Neurobehavioral Functioning in Pediatric Brain Tumor Patients After Proton Beam Radiation Treatment

NCT01180881

COMPLETED Phase 4

Diagnostic Utility of Attention Deficit Hyperactivity Disorder (ADHD) by Brain Activity Flow Patterns Analysis Using Evoked Response Potentials

NCT01063153

COMPLETED NA

Statin Therapy to Improve Atherosclerosis in HIV Patients

NCT00965185

COMPLETED NA

Functional MRI of Relaxation Response Training in Adults With Attention-Deficit/Hyperactivity Disorder

NCT01404273

TERMINATED Phase 3

Creatine Safety, Tolerability, & Efficacy in Huntington's Disease (CREST-E)

NCT00712426

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Phase Distribution

PhaseTrial count
Phase 1 226
Phase 2 289
Phase 3 58
Phase 4 182

What is open in the Massachusetts General Hospital pipeline

336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).

Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).

Top condition: Depression (29 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.