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NCT00833781 · ClinicalTrials.gov registry record · Phase 1
A Pilot Study of a Dendritic Cell Vaccine in HIV-1 Infected Subjects
A Phase 1 study, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- Phase 1
- Development phase
- 15
- Enrollment target
NCT00833781: Completed Phase 1 study, sponsored by Massachusetts General Hospital.
NCT00833781 is a Phase 1 study that has completed, run by Massachusetts General Hospital. The registered enrollment target is 15 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00833781, a Phase 1 study, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 15 participants
- Enrollment target
Study Summary
The purpose of the study is to find out whether an experimental autologous dendritic cell vaccine is safe, well tolerated, and whether it can strengthen the immune system's response to HIV.
Primary Outcome
Number of participants with grade 3 or 4 adverse events related to vaccination
Interventions
- BIOLOGICAL mRNA-transfected autologous dendritic cells
- BIOLOGICAL autologous dendritic cells with no mRNA transfection
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2009-08 |
| Est. Completion | 2013-12 |
| Phase | Phase 1 |
What the finished NCT00833781 record still lists
NCT00833781 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% lower).
The record links to 0 conditions, and to 2 interventions - of which mRNA-transfected autologous dendritic cells is the first listed.
NCT00833781 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00833781 about?
NCT00833781 is a clinical study titled "A Pilot Study of a Dendritic Cell Vaccine in HIV-1 Infected Subjects". The purpose of the study is to find out whether an experimental autologous dendritic cell vaccine is safe, well tolerated, and whether it can strengthen the immune system's response to HIV.
What is the current status of trial NCT00833781?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 15 participants. The study started on 2009-08. Estimated completion is 2013-12.
What interventions are being tested in trial NCT00833781?
The interventions under investigation include: mRNA-transfected autologous dendritic cells (BIOLOGICAL), autologous dendritic cells with no mRNA transfection (BIOLOGICAL).
Who is sponsoring clinical trial NCT00833781?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00833781's enrollment target sits among peer trials
15 1798th of 2000 higher than 157 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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