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NCT00973752 · ClinicalTrials.gov registry record · Phase 2

Treatment of Older Adults With Acute Lymphoblastic Leukemia

A Phase 2 study, sponsored by Massachusetts General Hospital.

Completed
Registry status
Phase 2
Development phase
30
Enrollment target

NCT00973752: Completed Phase 2 study, sponsored by Massachusetts General Hospital.

NCT00973752 is a Phase 2 study that has completed, run by Massachusetts General Hospital. The registered enrollment target is 30 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00973752, a Phase 2 study, has completed, sponsored by Massachusetts General Hospital.

COMPLETED
Registry status
Phase 2
Development phase
30 participants
Enrollment target

Study Summary

The purpose of this study is to determine the safety and effectiveness of a multi-drug regimen (which includes prednisone, vincristine, cytarabine, doxorubicin, 6 mercaptopurine, and methotrexate) which is considered standard treatment for children and young adults with acute lymphoblastic leukemia (ALL), in combination with PEG-asparaginase and clofarabine to treat older adults with ALL. PEG-asparaginase has been used in chemotherapy treatment regimens for both children and adults with ALL. Clofarabine has been used in chemotherapy treatment regimens for children with ALL and has been shown to decrease the number of leukemia cells. Participants with leukemia that has an abnormal chromosome, called the Philadelphia chromosome, will also be given imatinib.

Interventions

  • DRUG Doxorubicin
  • DRUG Vincristine
  • DRUG Prednisone
  • DRUG Cytarabine
  • DRUG PEG-asparaginase

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2009-08
Est. Completion 2016-04
Phase Phase 2

Sponsor

Massachusetts General Hospital

2,032 total trials

What the Registry Record Tells You About NCT00973752

The ClinicalTrials.gov registry entry for NCT00973752 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Doxorubicin is the first listed.

NCT00973752 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00973752 about?

NCT00973752 is a clinical study titled "Treatment of Older Adults With Acute Lymphoblastic Leukemia". The purpose of this study is to determine the safety and effectiveness of a multi-drug regimen (which includes prednisone, vincristine, cytarabine, doxorubicin, 6 mercaptopurine, and methotrexate) which is considered standard treatment for children and young adults with acute lymphoblastic leukemia ...

What is the current status of trial NCT00973752?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2009-08. Estimated completion is 2016-04.

What interventions are being tested in trial NCT00973752?

The interventions under investigation include: Doxorubicin (DRUG), Vincristine (DRUG), Prednisone (DRUG), Cytarabine (DRUG), PEG-asparaginase (DRUG).

Who is sponsoring clinical trial NCT00973752?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.