Massachusetts General Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).
Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.
Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.
Top-decile sponsor footprint
Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Open and recent trials
2,032 total, page 27 of 41
The Effect of OASIS Ultra on Critical Sized Wound Healing
NCT01848821
Removal of Anti-Angiogenic Proteins in Preeclampsia Before Delivery
NCT01404910
Brentuximab Vedotin + Re-induction Chemotherapy for AML
NCT01830777
HCV-RNA Kinetics During Sorafenib for Hepatocellular Carcinoma (HCC)
NCT01849588
Non-invasive Brain Modulation for Weight Maintenance
NCT01793766
Treatment of Complex Regional Pain Syndrome With Once Daily Gastric-Retentive Gabapentin (Gralise)
NCT01623271
Study of Sulfasalazine in Treating Painful Neuropathy
NCT01667029
Ectopic Lipid Deposition and Insulin Resistance in After Treatment of Acromegaly
NCT01819883
Trial of Low Field Magnetic Stimulation Augmentation of Antidepressant Therapy in Treatment-Resistant Depression
NCT01654796
Alisertib for Acute Myeloid Leukemia
NCT01779843
Study to Evaluate Effect of Nebivolol on Angina in Women With Microvascular Disease
NCT01665508
Effect of Body Positioning on Upper Airway Patency During Induction of Anesthesia in Obese Patients
NCT01811069
The Summer Camp Study: Blood Glucose Control With a Bi-Hormonal Bionic Endocrine Pancreas
NCT01833988
Lenalidomide/Bortezomib/Dexamethasone for Multiple Myeloma (MM)
NCT01782963
Positive Psychology for Mood Disorders
NCT01820286
Renal Allograft Tolerance Through Mixed Chimerism
NCT01780454
Inpatient Closed-loop Glucose Control
NCT01819844
Positive Psychology to Improve Cardiac Health Behaviors
NCT01807442
The Effect of the MedSentry System on Medication Adherence
NCT01814696
Investigation of Brain Network Dynamics in Depression
NCT01931995
Mindfulness Therapy on Disrupted Sleep in Bipolar Disorder
NCT01764035
Evaluation of Pulmonary Perfusion Heterogeneity and Compliance in Patients With Pulmonary Hypertension Using Positron Emission Tomography Imaging
NCT01461343
Proton Radiation for Lymphoma Involving Mediastinum
NCT01751412
Off-the-Shelf Splints Versus Occupational Therapy Splints for Treatment of Trapeziometacarpal Arthrosis
NCT01775670
Adjunctive Isradipine for the Treatment of Bipolar Depression
NCT01784666
OFDI Capsule Imaging in Patients With Atrial Fibrillation Undergone Radio Frequency (RF) Ablation
NCT02204566
The Learning and Memory of the Experience of Pain
NCT01731314
Self Focus in Bipolar Disorder: A Functional Magnetic Resonance Imaging (fMRI) Study
NCT02253225
Intra-operative Digital vs. Standard Mammography
NCT01766102
Acromegaly Treatment Quality of Life Study
NCT01732406
High Dose Preoperative Cholecalciferol Supplementation and Perioperative Vitamin D Status
NCT01689779
The Effects of General Anesthetics on Upper Airway Collapsibility in Healthy Subjects
NCT01557920
Carbamylation in Renal Disease-modulation With Amino Acid Therapy
NCT01612429
Sorafenib + mFOLFOX for Hepatocellular Carcinoma
NCT01775501
Brief Sleep Intervention for Bipolar Disorder
NCT01764074
Acute Effect of Teriparatide With Bisphosphonate or Denosumab on Bone Resorption
NCT01750086
Outpatient Automated Blood Glucose Control With a Bi-hormonal Bionic Endocrine Pancreas
NCT01762059
Ketamine Versus Placebo for Treatment Resistant Major Depressive Disorder
NCT01667926
AUY922 for Advanced ALK-positive NSCLC
NCT01752400
Combined BRAF-Targeted Therapy & Immunotherapy for Melanoma
NCT01754376
Effect of Acupuncture and Pain Medication on Radicular Pain Using QST
NCT01678586
Lenalidomide Plus Bendamustine and Rituximab for Untreated CLL/SLL
NCT01400685
Characterization of Transient Alterations of Cutaneous Sensory Nerve Function by Cryolipolysis
NCT01673113
Effects of Newly-Initiated QUAD Therapy on Aortic/Coronary Inflammation in ART-Naïve Infected Patients
NCT01766726
Comparative Effectiveness of Post-Discharge Strategies for Hospitalized Smokers
NCT01714323
Critical Care Observation of Motor Activity (COMA) and SICU Outcomes
NCT02994641
Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders
NCT01758042
Detecting EGFR T790M Mutations From Circulating Tumor Cells
NCT01734915
Fecal Microbiota Transplant (FMT) for Relapsing C. Difficile Infection in Adults and Children Using a Frozen Inoculum
NCT01704937
A Double-Blind Comparison of Naltrexone and Placebo in Adults With Attention Deficit Hyperactivity Disorder
NCT01721330
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 226 |
| Phase 2 | 289 |
| Phase 3 | 58 |
| Phase 4 | 182 |
Therapeutic Areas
What is open in the Massachusetts General Hospital pipeline
336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).
Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).
Top condition: Depression (29 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.