Massachusetts General Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).
Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.
Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.
Top-decile sponsor footprint
Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Open and recent trials
2,032 total, page 26 of 41
Bevacizumab w / Temozolomide PET & Vascular MRI For GBM
NCT01987830
An Open-Label Trial of Oxytocin in Adolescents With Autism Spectrum Disorders
NCT01931033
Meloxicam vs Placebo for Mobilization
NCT02003625
Trial of a Positive Psychology Intervention in Major Depressive Disorder
NCT02004145
Galectin-3 Blockade in Patients With High Blood Pressure
NCT01960946
Effect of Video Monitor Size on Adenoma Detection Rate
NCT01952418
Children's Use of the Built Environment for Physical Activity
NCT01939405
Safety and Efficacy of Squaric Acid Dibutyl Ester for the Treatment of Herpes Labialis
NCT01971385
A Pilot Study of Optical Molecular Imaging for Percutaneous Biopsy of Hepatocellular Carcinoma Using Indocyanine Green
NCT01962649
Cessation of Long-term Opioid Therapy in Chronic Pain Patients
NCT02132221
Phase I Trial of Brentuximab Vedotin for Refractory Chronic Graft-vs.-Host Disease (GVHD)
NCT01940796
Genetics of QT Response to Moxifloxacin
NCT01936480
A Registry to Determine the Clinical and Genetic Risk Factors for Torsade De Pointes
NCT02439645
Proof-of-Concept Trial of CERC-501 Augmentation of Antidepressant Therapy in Treatment-Resistant Depression
NCT01913535
Tivozanib + Enzalutamide in Adv Prostate Cancer
NCT01885949
Integrating Tobacco Treatment Into Cancer Care: A Randomized Controlled Comparative Effectiveness Trial
NCT01871506
Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study)
NCT02105298
Factors Associated With Radiographic Pathophysiology for Trapeziometacarpal Arthrosis in Patients Not Seeking Care for This Condition
NCT02252939
Cabozantinib (XL-184) Monotherapy for Advanced Cholangiocarcinoma
NCT01954745
Effectiveness of DECIDE in Patient-Provider Communication, Therapeutic Alliance & Care Continuation
NCT01947283
L-Serine Supplementation in Hereditary Sensory Neuropathy Type 1
NCT01733407
Ponatinib in Advanced NSCLC w/ RET Translocations
NCT01813734
Improving Care After Chemotherapy
NCT01944137
Prospective Evaluation of a Vancomycin Nomogram With a Continuous Infusion of Vancomycin for Surgical ICU Patients
NCT01786161
Radiation w/FOLFIRINOX-Losartan for Pancreatic Cancer
NCT01821729
Study of Growth Hormone and Bone in Obesity
NCT01724489
Tolerance Following Peanut Oral Immunotherapy
NCT01750879
Fecal Microbiota Transplant for Relapsing Clostridium Difficile Infection in Adults and Children Using a Frozen Encapsulated Inoculum
NCT01914731
Boosting Emotions & Happiness in Outpatients Living With Diabetes
NCT02736084
Gilenya in Amyotrophic Lateral Sclerosis (ALS)
NCT01786174
Proton Beam Teletherapy for Post-Hysterectomy Cancers of the Uterus and Cervix
NCT01600040
Chest Wall Influence on Respiratory System Mechanics in Morbidly Obese Patients
NCT02105220
Testosterone Antidepressant Augmentation in Women
NCT01783574
Phase I Study of Olaparib and Temozolomide for Ewings Sarcoma or Rhabdoomyosarcoma
NCT01858168
Improving Management of Breathlessness in Patients With Lung Cancer
NCT01937637
The Effect of Feedback Regarding Illness Behavior on Patient Satisfaction in Hand Surgery
NCT02209246
Longitudinal Study of Outcomes Measures in ALS Trials
NCT01911130
An Open-Label Trial of Buspirone for the Treatment of Anxiety in Youth With Autism Spectrum Disorders
NCT01850355
Phase 2 Study of AUY922 in NSCLC Patients With Exon 20 Insertion Mutations in EGFR
NCT01854034
Concurrent Chemoradiation + 5-FU + Mitomycin-C in Anal Carcinoma
NCT01858025
An Open-label Study to Identify Molecular Markers of Steroid Resistance
NCT01616160
Kisspeptin in the Evaluation of Delayed Puberty
NCT01438034
Tivozanib for Recurrent Glioblastoma
NCT01846871
Sensory and Connectivity Abnormalities in Autism Spectrum Disorders
NCT00956579
Low-Dose Naltrexone (LDN) for Depression Relapse and Recurrence
NCT01874951
Participant Database for Autism Research Studies
NCT00549731
Pilot Study of Cognitive Behavioral Therapy for Anxiety and Bipolar I Disorder
NCT01892306
Using SMART Experimental Design to Personalize Treatment for Child Depression
NCT01880814
Indocyanine Green Fluorescence Uptake in Human Carotid Artery Plaque
NCT01873716
Utility of Novel BRAF Test for Melanoma
NCT01840527
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 226 |
| Phase 2 | 289 |
| Phase 3 | 58 |
| Phase 4 | 182 |
Therapeutic Areas
What is open in the Massachusetts General Hospital pipeline
336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).
Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).
Top condition: Depression (29 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.