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NCT01931995 · ClinicalTrials.gov registry record · NA
Investigation of Brain Network Dynamics in Depression
A NA study, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- NA
- Development phase
- 45
- Enrollment target
NCT01931995: Completed NA study, sponsored by Massachusetts General Hospital.
NCT01931995 is a NA study that has completed, run by Massachusetts General Hospital. The registered enrollment target is 45 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01931995, a NA study, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 45 participants
- Enrollment target
Study Summary
This research study is being done to gain a better understanding about brain networks that may be involved in depression. The investigators plan to examine how these networks change after the brain is stimulated with "Transcranial Magnetic Stimulation" (TMS). TMS is a way of stimulating the brain in order to mildly activate or mildly suppress different brain areas, and is used to treat some forms of depression. It is hoped that this study will facilitate learning more about the structure and function of different brain areas and the ways that they are interconnected to form networks, both in depressed people and in people without depression. In this research study, the effects of TMS will be measured by obtaining "pictures" of the brain with "Magnetic Resonance Imaging" (MRI) and with "Positron Emission Tomography" (PET). More specifically, this will be accomplished with a combined MRI and PET scanner, which is capable of simultaneously obtaining both MRI and PET images of the brain. This scanning paradigm will allow the assessment of local metabolic changes resulting from TMS (with PET images) and brain network changes resulting from TMS (with fMRI). Changes resulting from TMS between 20 subjects with depression and 20 healthy volunteers will be calculated and will form the main outcome measure.
Interventions
- DEVICE TMS positively correlated DLPFC
- PROCEDURE TMS to negatively correlated DLPFC
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 45 participants |
| Start Date | 2013-02 |
| Est. Completion | 2018-07 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01931995
The ClinicalTrials.gov registry entry for NCT01931995 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 45 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which TMS positively correlated DLPFC is the first listed.
NCT01931995 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01931995 about?
NCT01931995 is a clinical study titled "Investigation of Brain Network Dynamics in Depression". This research study is being done to gain a better understanding about brain networks that may be involved in depression. The investigators plan to examine how these networks change after the brain is stimulated with "Transcranial Magnetic Stimulation" (TMS). TMS is a way of stimulating the brain in...
What is the current status of trial NCT01931995?
This trial is currently completed. It is a NA study. The enrollment target is 45 participants. The study started on 2013-02. Estimated completion is 2018-07.
What interventions are being tested in trial NCT01931995?
The interventions under investigation include: TMS positively correlated DLPFC (DEVICE), TMS to negatively correlated DLPFC (PROCEDURE).
Who is sponsoring clinical trial NCT01931995?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
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