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NCT01557920 · ClinicalTrials.gov registry record · Phase 4
The Effects of General Anesthetics on Upper Airway Collapsibility in Healthy Subjects
A Phase 4 study, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- Phase 4
- Development phase
- 18
- Enrollment target
NCT01557920: Completed Phase 4 study, sponsored by Massachusetts General Hospital.
NCT01557920 is a Phase 4 study that has completed, run by Massachusetts General Hospital. The registered enrollment target is 18 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01557920, a Phase 4 study, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 18 participants
- Enrollment target
Study Summary
The investigators hypothesize that propofol, when compared to sevoflurane, causes the upper airway to collapse more easily and causes less activity in the tongue muscle. Additionally, the investigators hypothesize that, under increased carbon dioxide concentrations of the air inhaled, the upper airway will be less likely to collapse under anesthesia and there will be increased activity in the tongue muscle under both propofol and sevoflurane, when compared to breathing normal concentrations of carbon dioxide, as in room air. Furthermore the investigators hypothesize that anesthesia disrupt the breathing swallow coordination, an effect additionally altered by increased carbon dioxide through increased respiratory drive.
Interventions
- DRUG Sevoflurane
- DRUG Propofol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2013-01 |
| Est. Completion | 2014-03 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01557920
The ClinicalTrials.gov registry entry for NCT01557920 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 18 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Sevoflurane is the first listed.
NCT01557920 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01557920 about?
NCT01557920 is a clinical study titled "The Effects of General Anesthetics on Upper Airway Collapsibility in Healthy Subjects". The investigators hypothesize that propofol, when compared to sevoflurane, causes the upper airway to collapse more easily and causes less activity in the tongue muscle. Additionally, the investigators hypothesize that, under increased carbon dioxide concentrations of the air inhaled, the upper airw...
What is the current status of trial NCT01557920?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 18 participants. The study started on 2013-01. Estimated completion is 2014-03.
What interventions are being tested in trial NCT01557920?
The interventions under investigation include: Sevoflurane (DRUG), Propofol (DRUG).
Who is sponsoring clinical trial NCT01557920?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
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