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NCT01766726 · ClinicalTrials.gov registry record
Effects of Newly-Initiated QUAD Therapy on Aortic/Coronary Inflammation in ART-Naïve Infected Patients
A clinical trial, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- 33
- Enrollment target
NCT01766726: Completed study, sponsored by Massachusetts General Hospital.
NCT01766726 is a clinical trial that has completed, run by Massachusetts General Hospital. The registered enrollment target is 33 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01766726 has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- 33 participants
- Enrollment target
Study Summary
The main aims of this study are to determine whether: a) ART-naïve HIV+ subjects have increased artherosclerotic plaque inflammation/vulnerability, b) newly-initiated QUAD/Stribild therapy will decrease plaque inflammation/vulnerability in these subjects, and c) QUAD/Stribild therapy will improve indices of immune dysregulation and lipid dysfunction as a mechanism of improved plaque inflammation/vulnerability. Parameters of lipid and immune function will also be assessed in healthy control subjects, for comparison.
Primary Outcome
Degree of aortic/coronary atherosclerotic plaque inflammation assessed via cardiac FDG-PET as target to background ratio (TBR) of the standardized uptake value (SUV).
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 33 participants |
| Start Date | 2012-12 |
| Est. Completion | 2016-01 |
What the finished NCT01766726 record still lists
NCT01766726 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 33 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT01766726 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01766726 about?
NCT01766726 is a clinical study titled "Effects of Newly-Initiated QUAD Therapy on Aortic/Coronary Inflammation in ART-Naïve Infected Patients". The main aims of this study are to determine whether: a) ART-naïve HIV+ subjects have increased artherosclerotic plaque inflammation/vulnerability, b) newly-initiated QUAD/Stribild therapy will decrease plaque inflammation/vulnerability in these subjects, and c) QUAD/Stribild therapy will improve in...
What is the current status of trial NCT01766726?
This trial is currently completed. The enrollment target is 33 participants. The study started on 2012-12. Estimated completion is 2016-01.
Who is sponsoring clinical trial NCT01766726?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
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