Massachusetts General Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).

2,032 total trials 336 currently recruiting 1284 completed early-phase tilt top decile by trial count

Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.

Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.

Top-decile sponsor footprint

Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,032 total, page 25 of 41

COMPLETED NA

Quincy Family, Youth & Technology For Lifestyle Change (FYT-4-LIFE) Study

NCT02324361

COMPLETED NA

Efficacy Study on Silver-coated ETT Cleaned With a Novel Device

NCT02120001

COMPLETED NA

Light Therapy for Moderate Traumatic Brain Injury

NCT02233413

COMPLETED NA

The Summer Camp Study 2: Blood Glucose Control With a Bi-Hormonal Endocrine Pancreas

NCT02105324

COMPLETED NA

Connect 4 Health: An Intervention to Improve Childhood Obesity Outcomes

NCT02124460

COMPLETED NA

Using Spectrally Encoded Confocal Microscopy (SECM) to Visualise the Esophagus Using an SECM Probe

NCT02210039

COMPLETED Phase 4

Pilot Study of Short-Course Glucocorticoids and Rituximab for Treatment of ANCA-Associated Vasculitis

NCT02169219

COMPLETED NA

The Effect of Questionnaire Content on Measures of Pain Intensity, Magnitude of Disability, and Symptoms of Depression in Patients With Arm Illness

NCT02209259

COMPLETED

Effects of Frailty, Sarcopenia and Muscle Wasting on Outcomes of Patients in the Surgical Intensive Care Unit

NCT02270502

COMPLETED NA

Determination of the Predictors of Nocturnal Desaturation in Postpartum Women

NCT02330055

COMPLETED Phase 4

Use of Negative Pressure Wound Therapy in High Risk Surgical Closed Incisions

NCT02137447

COMPLETED Phase 4

Methylphenidate ER Liquid Formulation in Adults With ASD and ADHD

NCT02096952

COMPLETED Phase 1

Infusion of T-Regulatory Cells in Kidney Transplant Recipients (The ONE Study)

NCT02091232

COMPLETED Phase 2

L-methylfolate Supplementation to OROS-Methylphenidate Pharmacotherapy in ADHD Adults

NCT01853280

COMPLETED Phase 1

Neuropeptides in Human Reproduction

NCT01952782

COMPLETED NA

A Multicenter Study of Outpatient Automated Blood Glucose Control With a Bihormonal Bionic Pancreas

NCT02092220

COMPLETED Phase 1

The Effect of Alendronate on the Immune Response to Hepatitis B Vaccine in Healthy Adults

NCT02057263

COMPLETED NA

Evaluation of Mind-body Educational Program to Enhance Resiliency and Reduce Burnout in First Year Residents

NCT02621788

COMPLETED

PET/MRI Imaging of Neuraxial Inflammation in Sciatica Patients

NCT02130271

COMPLETED Phase 2

A Randomized, Controlled Trial of Intranasal Oxytocin as an Adjunct to Behavioral Therapy for Autism Spectrum Disorder

NCT01914939

COMPLETED NA

International Latino Research Partnership

NCT02038855

COMPLETED NA

Dietary Intake and Circulating Levels of Branched Chain Amino Acids

NCT02110602

TERMINATED Phase 1

Phase I Trial of LDE225 for Steroid-refractory Chronic GVHD After Allogeneic HSCT

NCT02086513

COMPLETED NA

The Impact of a "Serious Game" on Improving Patient's Medication Knowledge

NCT01786044

COMPLETED NA

Resiliency Training for Patients With Neurofibromatosis Via Videoconferencing With Skype

NCT02298270

COMPLETED NA

Pain Management in Cancer Patients Using a Mobile Application

NCT02069743

COMPLETED

Pulmonary Perfusion Heterogeneity in Patients With CTEPH Using Functional PET Imaging

NCT02114047

COMPLETED NA

FMISO PET Study of Glioblastoma

NCT02076152

COMPLETED NA

Abiraterone Acetate for Castrate Resistant Prostate Cancer

NCT01961843

COMPLETED NA

The Effects of Ketamine on Respiratory Stimulation and Transpulmonary Pressures

NCT01969227

COMPLETED NA

Text Messaging Adherence to Stimulant Medication

NCT01967485

COMPLETED NA

Advanced Neuroimaging Evaluation of CNS Changes Associated With Efavirenz Therapy Switch to an Raltegravir-based Regimen

NCT01978743

COMPLETED Phase 4

Open-Label Study of N-Acetylcysteine in Children and Adolescents 5-17 With Bipolar Spectrum Disorders

NCT02357290

COMPLETED NA

Advanced Neuroimaging Evaluation of the Central Nervous System Biological Changes Associated With Efavirenz Therapy and Switch to an Elvitegravir-based Regimen

NCT01929759

COMPLETED NA

Gabapentin for Insomnia Symptoms and Nighttime Vasomotor Symptoms (VMS) in Peri- and Postmenopausal Women

NCT02040532

COMPLETED NA

Randomized Trial of Financial Incentives to Reduce Sugar-sweetened Beverage Purchases by Low-income, Latino Families

NCT01990508

COMPLETED

Neck Fat Accumulation and Its Relationship to Cardiovascular Risk and Metabolic Syndrome

NCT02205021

COMPLETED Phase 3

Cholecalciferol Supplementation for Sepsis in the ICU

NCT01896544

COMPLETED NA

Ensuring Communication in Hospice by Oncology Study (ECHO)

NCT02069769

COMPLETED Early Phase 1

MET-PET for Newly Diagnosed Glioblastoma

NCT01867593

COMPLETED NA

Hemodynamic and Respiratory Variations During Laparoscopic Surgery With and Without Deep Neuromuscular Blockade.

NCT02025075

TERMINATED Phase 4

Slowed Carboplatin Infusion for Ovarian Cancer Patients Receiving Carboplatin Re-Treatment

NCT02035345

COMPLETED

Fat Distribution and Glucose Metabolism in Williams Syndrome

NCT01864304

TERMINATED Phase 1

Pilot Study of GVAX in Colorectal Cancer Cells

NCT01952730

COMPLETED NA

Comparison of Treatments for Barrett's Esophagus With High-Grade Dysplasia/Early Adenocarcinoma

NCT01961778

COMPLETED

Stratification of Patients With Chronic Liver Disease Using Multi Spectral CT

NCT01825213

COMPLETED NA

Photometric Stereo Endoscopy (PSE) as a Tool for Imaging the Rectum and Colon

NCT01979458

COMPLETED NA

Positive Psychology to Improve Healthy Behaviors After an Acute Coronary Syndrome

NCT02004158

COMPLETED Phase 4

An Open-Label Study of Naltrexone in Adults With Attention Deficit Hyperactivity Disorder.

NCT01873729

COMPLETED Phase 1

Phase I Trial of Cabozantinib in Patients With Relapsed or Refractory Acute Myeloid Leukemia

NCT01961765

← Previous Page 25 of 41 Next →

Phase Distribution

PhaseTrial count
Phase 1 226
Phase 2 289
Phase 3 58
Phase 4 182

What is open in the Massachusetts General Hospital pipeline

336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).

Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).

Top condition: Depression (29 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.