Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02105220 · ClinicalTrials.gov registry record

Chest Wall Influence on Respiratory System Mechanics in Morbidly Obese Patients

A clinical trial, sponsored by Massachusetts General Hospital.

Completed
Registry status
14
Enrollment target

NCT02105220: Completed study, sponsored by Massachusetts General Hospital.

NCT02105220 is a clinical trial that has completed, run by Massachusetts General Hospital. The registered enrollment target is 14 participants. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist → Add completion date to calendar (.ics) →

The verdict

NCT02105220 has completed, sponsored by Massachusetts General Hospital.

COMPLETED
Registry status
14 participants
Enrollment target

Study Summary

The goal of this study is to describe the influence of the chest wall on the respiratory system mechanics in morbidly obese patients and in patients with high intra-abdominal pressure. The effects of increasing and decreasing positive end-expiratory pressure (PEEP) on chest wall and total respiratory system mechanics, lung volumes and gas exchange will be evaluated, both during controlled and assisted mechanical ventilation. Patients will be studied, first, during the acute phase of respiratory failure, when requiring intubation and controlled mechanical ventilation. Then, patients will be evaluated again during weaning from the ventilator to assess the influence of PEEP in assisted ventilation prior to extubation.

Primary Outcome

EELV variation at different levels of PEEP in mechanically ventilated and sedated morbidly obese patients and patients with intraabdominal hypertension

Interventions

  • OTHER Respiratory mechanics assessment

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2013-08
Est. Completion 2015-03
Massachusetts General Hospital

2,032 total trials

What the finished NCT02105220 record still lists

NCT02105220 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 14 participants, a relatively small participant target.

The record links to 0 conditions, and to 1 intervention - of which Respiratory mechanics assessment is the first listed.

NCT02105220 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02105220 about?

NCT02105220 is a clinical study titled "Chest Wall Influence on Respiratory System Mechanics in Morbidly Obese Patients". The goal of this study is to describe the influence of the chest wall on the respiratory system mechanics in morbidly obese patients and in patients with high intra-abdominal pressure. The effects of increasing and decreasing positive end-expiratory pressure (PEEP) on chest wall and total respirato...

What is the current status of trial NCT02105220?

This trial is currently completed. The enrollment target is 14 participants. The study started on 2013-08. Estimated completion is 2015-03.

What interventions are being tested in trial NCT02105220?

The interventions under investigation include: Respiratory mechanics assessment (OTHER).

Who is sponsoring clinical trial NCT02105220?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02523092 · 14 participants · Phase 4

    Use of CXCL9 as a Biomarker of Acthar Efficacy

  • NCT04263285 · 14 participants · NA

    Treatment of Depression Post-SCI

  • NCT04743271 · 14 participants · NA

    Food and Circadian Timing

  • NCT05065671 · 14 participants · Phase 1

    Microbiome Derived Metabolism and Pharmacokinetics

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT02105220, the US trial registry maintained by the National Library of Medicine. NCT02105220 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.