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NCT02486757 · ClinicalTrials.gov registry record · Early Phase 1
Investigation of Female Reproductive Hormone Dynamics During Adolescence
A Early Phase 1 study, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 9
- Enrollment target
NCT02486757: Completed Early Phase 1 study, sponsored by Massachusetts General Hospital.
NCT02486757 is a Early Phase 1 study that has completed, run by Massachusetts General Hospital. The registered enrollment target is 9 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02486757, a Early Phase 1 study, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 9 participants
- Enrollment target
Study Summary
Irregular menstrual cycles are common in girls for several years after their first menstrual period. The cause of abnormal menstrual cycles during this time is not well-understood. The purpose of this study is to: 1) monitor girls during a menstrual cycle (with blood and urine sampling and serial pelvic ultrasounds) to identify those girls who do not ovulate (release of an egg from the ovary), and 2) determine whether cycles can be corrected by treating girls with a short course of low-dose estrogen and progesterone.
Primary Outcome
serum progesterone \> 3 ng/ml or presence of corpus luteum on pelvic ultrasound
Interventions
- DRUG transdermal estradiol
- DRUG micronized progesterone
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2015-04 |
| Est. Completion | 2016-03-01 |
| Phase | Early Phase 1 |
What the finished NCT02486757 record still lists
NCT02486757 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (83% lower).
The record links to 0 conditions, and to 2 interventions - of which transdermal estradiol is the first listed.
NCT02486757 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02486757 about?
NCT02486757 is a clinical study titled "Investigation of Female Reproductive Hormone Dynamics During Adolescence". Irregular menstrual cycles are common in girls for several years after their first menstrual period. The cause of abnormal menstrual cycles during this time is not well-understood. The purpose of this study is to: 1) monitor girls during a menstrual cycle (with blood and urine sampling and serial pe...
What is the current status of trial NCT02486757?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 9 participants. The study started on 2015-04. Estimated completion is 2016-03-01.
What interventions are being tested in trial NCT02486757?
The interventions under investigation include: transdermal estradiol (DRUG), micronized progesterone (DRUG).
Who is sponsoring clinical trial NCT02486757?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02486757's enrollment target sits among peer trials
9 1746th of 2000 higher than 219 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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