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NCT02428855 · ClinicalTrials.gov registry record · Phase 2

Phase II Trial of Dasatinib in Patients With Isocitrate Dehydrogenase (IDH)-Mutant Advanced Intrahepatic Cholangiocarcinoma

A Phase 2 study, sponsored by Massachusetts General Hospital.

Completed
Registry status
Phase 2
Development phase
8
Enrollment target

NCT02428855: Completed Phase 2 study, sponsored by Massachusetts General Hospital.

NCT02428855 is a Phase 2 study that has completed, run by Massachusetts General Hospital. The registered enrollment target is 8 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT02428855, a Phase 2 study, has completed, sponsored by Massachusetts General Hospital.

COMPLETED
Registry status
Phase 2
Development phase
8 participants
Enrollment target

Study Summary

This research study is studying Dasatinib as a possible treatment for cancer of bile ducts.

Primary Outcome

The number of participants that achieved either a complete or partial response, as assessed by Response Criteria in Solid Tumors (RECIST 1.1) * Complete Response (CR): Disappearance of all target lesions. Any pathological lymph nodes (whether target or non-target) must have reduction in short axis to \<10 mm. * Partial Response (PR): At least a 30% decrease in the sum of diameters of target lesions, taking as reference the baseline sum diameters.

Interventions

  • DRUG Dasatinib

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 2015-04
Est. Completion 2018-02
Phase Phase 2
Massachusetts General Hospital

2,032 total trials

What the finished NCT02428855 record still lists

NCT02428855 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (94% lower).

The record links to 0 conditions, and to 1 intervention - of which Dasatinib is the first listed.

NCT02428855 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02428855 about?

NCT02428855 is a clinical study titled "Phase II Trial of Dasatinib in Patients With Isocitrate Dehydrogenase (IDH)-Mutant Advanced Intrahepatic Cholangiocarcinoma". This research study is studying Dasatinib as a possible treatment for cancer of bile ducts.

What is the current status of trial NCT02428855?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 8 participants. The study started on 2015-04. Estimated completion is 2018-02.

What interventions are being tested in trial NCT02428855?

The interventions under investigation include: Dasatinib (DRUG).

Who is sponsoring clinical trial NCT02428855?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02428855's enrollment target sits among peer trials

8 1990th of 2000 higher than 5 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02428855, the US trial registry maintained by the National Library of Medicine. NCT02428855 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.