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NCT02323295 · ClinicalTrials.gov registry record · NA
Effect of High Doses of Radiation on Bone Structure and Metabolism
A NA study, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- NA
- Development phase
- 12
- Enrollment target
NCT02323295: Completed NA study, sponsored by Massachusetts General Hospital.
NCT02323295 is a NA study that has completed, run by Massachusetts General Hospital. The registered enrollment target is 12 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02323295, a NA study, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
Study Summary
This study is designed to characterize the effects of high energy radiation on bone breakdown, with a specific interest in reducing the rate of sacral fractures. Although radiation is very important in managing tumors, it is related to complications such as bone fractures. In this research study, the investigators are looking to determine changes in blood markers, bone density, and bone structure following radiation and to better understand the reason for these changes.
Primary Outcome
Trabecular bone mineral density will be measured in mg/cm3 using volumetric Quantitative Computed Tomography (QCT) of L1, L2 and the vertebrae adjacent to the tumor.
Interventions
- RADIATION Radiation (Surgical Arm)
- RADIATION Radiation (Non-surgical Arm)
- PROCEDURE Malignant Tumor Surgery
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2015-07 |
| Est. Completion | 2019-07 |
| Phase | NA |
What the finished NCT02323295 record still lists
NCT02323295 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 3 interventions - of which Radiation (Surgical Arm) is the first listed.
NCT02323295 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02323295 about?
NCT02323295 is a clinical study titled "Effect of High Doses of Radiation on Bone Structure and Metabolism". This study is designed to characterize the effects of high energy radiation on bone breakdown, with a specific interest in reducing the rate of sacral fractures. Although radiation is very important in managing tumors, it is related to complications such as bone fractures. In this research study, th...
What is the current status of trial NCT02323295?
This trial is currently completed. It is a NA study. The enrollment target is 12 participants. The study started on 2015-07. Estimated completion is 2019-07.
What interventions are being tested in trial NCT02323295?
The interventions under investigation include: Radiation (Surgical Arm) (RADIATION), Radiation (Non-surgical Arm) (RADIATION), Malignant Tumor Surgery (PROCEDURE).
Who is sponsoring clinical trial NCT02323295?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02323295's enrollment target sits among peer trials
12 1913th of 2000 higher than 74 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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