Massachusetts General Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).
Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.
Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.
Top-decile sponsor footprint
Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Open and recent trials
2,032 total, page 24 of 41
Mobile Application for Improving Symptoms and Adherence to Oral Chemotherapy in Patients With Cancer
NCT02157519
Mobile App of CBT for Anxiety and Cancer
NCT02286466
Behavioral and Neural Response to Memantine in Adolescents With Autism Spectrum Disorder
NCT01972074
Renal Allograft Tolerance Through Mixed Chimerism (Belatacept)
NCT02314403
Relationship Between Psychosocial Factors, Health Literacy, Quality of Life and Satisfaction With Medical Visits in Adults With NF
NCT02435628
Velcade and Lenalidomide in Patients With Relapsed AML and MDS After Allogeneic Stem Cell Transplantation
NCT02312102
Combined Bone Marrow and Renal Transplantation for Hematologic Disorders With End Stage Renal Disease
NCT02158052
Researching Emotions And Cardiac Health
NCT02737761
Resiliency Training for Adolescent Neurofibromatosis Patients Via Videoconferencing With Skype
NCT02387177
A Pilot Study of Inosine in Amyotrophic Lateral Sclerosis (ALS)
NCT02288091
Polysomnographic Study Comparing the Use of Dexmedetomidine and Zolpidem to Induce Natural Sleep
NCT01485393
Augmentation of Exposure Therapy for High Levels of Social Anxiety Using Post-exposure Naps
NCT02325128
Lenalidomide in Combination With Microtransplantation as Post-remission Therapy in AML
NCT02255162
Placebo Controlled Study of Fecal Microbiota Transplant (FMT) for a First or Second Episode of C. Difficile Infection in Adults Using a Frozen Encapsulated Inoculum
NCT02343328
Double-Blind, Placebo-Controlled Trial of Ketamine Therapy in Treatment-Resistant Depression (TRD)
NCT01920555
Fear Extinction and Mechanisms of Change in Obsessive Compulsive Disorder
NCT02467374
A Trial of Integrating SBRT With Targeted Therapy in Stage IV Oncogene-driven NSCLC
NCT02314364
Oxytocin Administration in BDD and OCD
NCT02671266
Pilot Study to Image the Esophagus Using a SECM Tethered Endoscopic Capsule
NCT02445014
Phase I Study of MLN 9708 in Addition to Chemotherapy for the Treatment of Acute Lymphoblastic Leukemia in Older Adults
NCT02228772
PET/CT Imaging Companion Study To ACTG A5314
NCT02312219
REAL HEALTH-Diabetes: Reach Ahead for Lifestyle and Health-Diabetes
NCT02320253
Enhancing Outcomes, Reducing Costs: Evaluating Peer Support for Mood Disorders
NCT02242669
Closed-Loop Glucagon Administration For Hypoglycemia Treatment
NCT02181127
Thermal Imaging to Diagnose and Monitor Suspected Bacterial Infections
NCT02292498
Reversal of General Anesthesia With Methylphenidate
NCT02051452
Oxytocin Effects on Food Motivation Pathways
NCT02276677
"ACT" for Parents of Children With Autism Spectrum Disorder
NCT02255786
Positive Psychology for ACS Patients: a Factorial Design Study
NCT02754895
Carfilzomib Plus Belinostat in Relapsed/Refractory NHL
NCT02142530
A Pilot Study of Neoadjuvant Therapy With Gemcitabine and Cisplatin in Patients With Resectable or Unresectable Intrahepatic Cholangiocarcinoma
NCT02256982
Pilot Study for Imaging of the Esophagus Using a Tethered Capsule OCT Endomicroscopy in the Primary Care Setting
NCT02445027
Impact of Weight Loss Surgery in Adolescents With NAFLD
NCT02952170
Effectiveness and Acceptability of MoodGYM in Treating Depressive Symptoms in Chinese Americans
NCT01851967
Staying Strong With Schools - A School-Based Resilience Support Intervention for Military-Connected Children
NCT02378051
Neuromodulation of Executive Function in the ADHD Brain
NCT04175028
Effect of Guanfacine on Opioid-induced Hyperalgesia (OIH) and Tolerance
NCT01681264
Phase II Study of Preoperative FOLFIRINOX Versus Gemcitabine/Nab-Paclitaxel in Patients With Resectable Pancreatic Cancer
NCT02243007
Effect of Guanfacine on the Reversal of Opioid-induced Hyperalgesia (OIH)
NCT02192398
2 Phase Use Of Educational Materials In Head And Neck Cancer Center
NCT02204631
Neural Changes Associated With a Mindfulness-based Intervention for Young Adults With Childhood Maltreatment
NCT02447744
Supportive Care Intervention In Patients Hospitalized For Hematopoietic Stem Cell Transplantation (Shield)
NCT02207322
Does Vitamin C Reduce Finger Stiffness After Distal Radius Fractures?
NCT02216812
Dietary Intake of Tryptophan and Metformin Response
NCT02184832
Assessing the Efficacy of Intravenous Acetaminophen Versus the Oral Formulation for Perioperative Pain Treatment
NCT02216682
Denosumab and Teriparatide Study (DATA-HD and DATA-EX)
NCT02176382
Treatment of Field Cancerization for Reduction in Tumor Burden - A Prospective Study
NCT02150863
An fMRI Study on Temporal Discounting in Bipolar Disorder
NCT02323763
Omega-3 Supplementation to ADHD Medication in Children
NCT02204410
Implementation of a Population Health Chronic Disease Management Program
NCT02812303
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 226 |
| Phase 2 | 289 |
| Phase 3 | 58 |
| Phase 4 | 182 |
Therapeutic Areas
What is open in the Massachusetts General Hospital pipeline
336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).
Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).
Top condition: Depression (29 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.