Massachusetts General Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).
Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.
Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.
Top-decile sponsor footprint
Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Open and recent trials
2,032 total, page 17 of 41
Building Infrastructure for Community Capacity in Accelerating Integrated Care
NCT04092777
Virtual Reality for Pain Management in Orthopaedic Patients
NCT04152447
Vagus Nerve Stimulation and Stress Reduction Training for Migraine
NCT03592329
EdemaWear to Reduce Edema in Hospitalized Patients With CVI:
NCT03904602
Gamma Induction for Alzheimer's Disease
NCT03880240
Mechanistic Studies on Video-guided Acupuncture Imagery Treatment of Knee Pain
NCT03261505
Age-dependency of Cornea Biomechanics Using OCT Vibrography
NCT03230981
Preventing Depression and Anxiety: A Cystic Fibrosis-Specific Cognitive Behavioral Therapy Intervention
NCT03992027
Pilot Trial of Contingency Management for Long-Term Cannabis Abstinence
NCT03786224
Mechanism of Action of Electroconvulsive Therapy
NCT04059952
Optimizing Medical "Teaming" on Resident Based Teams
NCT05213117
Version 2 of the Smoking Cessation Smartphone App "Smiling Instead of Smoking" (SiS)
NCT03951766
Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients
NCT03202641
A Clinical Trial Via Telepsychiatry of Treatments for the Management of Emotional Dysregulation in Youth
NCT03911414
Liposomal Bupivicaine for Skin Graft Donor Sites in Burn Patients
NCT03705637
INCB039110 in Combination With Dabrafenib and Trametinib in Patients With BRAF-mutant Melanoma and Other Solid Tumors.
NCT03272464
Natural Treatments for the Management of Emotional Dysregulation in Youth With Non-verbal Learning Disability (NVLD) and/or Autism Spectrum Disorders (ASD)
NCT03757585
The Bihormonal iLet Bionic Pancreas Feasibility Study
NCT03840278
Predicting Disease Progression and/or Recurrence in Cancer
NCT04776837
Virtual Reality Alternative to Pharmacological Sedation During Colonoscopy
NCT04349150
Optimized Health-Related Social Needs Screening and Community Linkages
NCT03834441
Comparative Effectiveness of Pharmacogenomics for Treatment of Depression
NCT03749629
Promoting Informed Decisions About Cancer Screening in Older Adults
NCT03959696
Rivaroxaban vs. Warfarin for Post Cardiac Surgery Atrial Fibrillation
NCT03702582
Managing Pain in Patients With MTP Arthritis
NCT04833608
Project Matter: Intervention to Improve HIV Self-care Among Men Who Have Sex With Men (MSM) With Substance Use Disorders
NCT03899220
Football Players Health Study In Person Assessments Study
NCT03866564
Mental Training for Adults With Mild Cognitive Impairment
NCT03895346
Assessing the Integration of Tobacco Cessation Treatment Into Lung Cancer Screening (LCS)
NCT03611881
A Care Management Intervention for Non-cardiac Chest Pain
NCT04904198
Randomized Control Trial of CO2 Laser to Treat Hypertrophic Burn Scar
NCT03692273
Individualizing Automated Closed Loop Glucose Control Through Pharmacokinetic Profiling in an Insulin-Only Bionic Pancreas
NCT03262116
Suvorexant on Sleep Disturbance in Patients With Chronic Insomnia and Suboptimally Controlled Type 2 Diabetes
NCT03818581
Preventing Depressive Relapse in Pregnant Women With Recurrent Depression
NCT03623620
Acupuncture to Reduce Anxiety in Alzheimer's Disease (AD) and AD Related Dementias
NCT03814382
Pilot Study of Cognitive Behavioral Therapy-Informed Physical Therapy Intervention in Functional Neurological Disorders
NCT03731078
Pilot Study of Neuromodulation for Enhancement of Emotion Regulation in Bipolar Mood Disorders
NCT03622749
A Virtual Reality Study of Cognitive Biases in Body Dysmorphic Disorder
NCT03773549
The Impact of Exercise-Induced Cardiac Remodeling on Myocardial Efficiency
NCT04580693
Healthy Mind Healthy You: A Study of Mindfulness
NCT03844321
A Geriatric Oncology Collaborative Care Intervention for Older Adults With Advanced Cancer
NCT03721926
Psychological Intervention for Caregivers of Patients With Malignant Gliomas
NCT03735498
Pan-genotypic Direct Acting Antiviral Therapy in Donor HCV-positive to Recipient HCV-negative Lung Transplant
NCT03625687
Multimodal Mobile Intervention Application (App) to Address Sexual Dysfunction in Hematopoietic Stem Cell Transplant Survivors
NCT03967379
Impact of Decision Aids in Urogynecology
NCT04369404
Supportive Oncology Care at Home for Patients With Pancreatic Cancer Receiving Preoperative FOLFIRINOX
NCT03798769
Growth Hormone Dynamics and Cardiac Steatosis in HIV
NCT03826160
Growth Hormone Releasing Hormone Analog to Improve Nonalcoholic Fatty Liver Disease and Associated Cardiovascular Risk
NCT03375788
IDH1 Inhibition Using Ivosidenib as Maintenance Therapy for IDH1-mutant Myeloid Neoplasms Following Allogeneic Stem Cell Transplantation
NCT03564821
M6620 (VX-970) in Selected Solid Tumors
NCT03718091
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 226 |
| Phase 2 | 289 |
| Phase 3 | 58 |
| Phase 4 | 182 |
Therapeutic Areas
What is open in the Massachusetts General Hospital pipeline
336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).
Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).
Top condition: Depression (29 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.