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NCT03202641 · ClinicalTrials.gov registry record · NA
Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients
A NA study, sponsored by Massachusetts General Hospital.
- Terminated
- Registry status
- NA
- Development phase
- 2
- Enrollment target
NCT03202641: Clinical Trial NA study, sponsored by Massachusetts General Hospital.
NCT03202641 is a NA study that was terminated before completion, run by Massachusetts General Hospital. The registered enrollment target is 2 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03202641, a NA study, was terminated before completion, sponsored by Massachusetts General Hospital.
- TERMINATED
- Registry status
- NA
- Development phase
- 2 participants
- Enrollment target
Study Summary
The goal of this interventional crossover study, in intubated and mechanically ventilated Acute Respiratory Distress Syndrome (ARDS) patients, is to compare two positive end-expiratory pressure (PEEP) titration techniques regarding: respiratory mechanics, gas exchange, changes in aeration, ventilation/perfusion matching its impact on cardiac function, especially the right heart (RH). The PEEP titration techniques are: PEEP selection based on low PEEP/high FiO2 table ("PEEPARDSnet") and lung recruitment maneuver (LRM) plus PEEPdec titration based on the best compliance of the respiratory system("PEEPLRM").
Primary Outcome
The primary endpoint of this study is to describe the airways driving pressures (defined as Plateau Pressure minus PEEP) during "PEEP ARDSnet" and "PEEP LRM".
Interventions
- PROCEDURE PEEP ARDSnet
- PROCEDURE PEEP LRM
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2019-06-19 |
| Est. Completion | 2020-05-12 |
| Phase | NA |
Why NCT03202641 stopped before completion
NCT03202641 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 2 interventions - of which PEEP ARDSnet is the first listed.
NCT03202641 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03202641 about?
NCT03202641 is a clinical study titled "Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients". The goal of this interventional crossover study, in intubated and mechanically ventilated Acute Respiratory Distress Syndrome (ARDS) patients, is to compare two positive end-expiratory pressure (PEEP) titration techniques regarding: respiratory mechanics, gas exchange, changes in aeration, ventilati...
What is the current status of trial NCT03202641?
This trial is currently terminated. It is a NA study. The enrollment target is 2 participants. The study started on 2019-06-19. Estimated completion is 2020-05-12.
What interventions are being tested in trial NCT03202641?
The interventions under investigation include: PEEP ARDSnet (PROCEDURE), PEEP LRM (PROCEDURE).
Who is sponsoring clinical trial NCT03202641?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03202641's enrollment target sits among peer trials
2 1997th of 2000 the lowest of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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