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NCT04059952 · ClinicalTrials.gov registry record
Mechanism of Action of Electroconvulsive Therapy
A clinical trial of Bipolar Depression and Unipolar Depression, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- 102
- Enrollment target
- 1
- Study location
NCT04059952: Completed study of Bipolar Depression and Unipolar Depression, sponsored by Massachusetts General Hospital.
NCT04059952 is a study of Bipolar Depression and Unipolar Depression that has completed, run by Massachusetts General Hospital. The registered enrollment target is 102 participants, below the 213-participant average among 29 other Bipolar Depression trials with a reported enrollment target (52% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04059952, a study of Bipolar Depression and Unipolar Depression, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- 102 participants
- Enrollment target
- 1
- Study location
Study Summary
This is an observational neuroimaging study assessing the effects of ECT on the brains of patients with unipolar and bipolar depression.
Primary Outcome
Measured by Magnetic Resonance Imaging, Key Nodes include Subgenual Cingulate, Dorsal Anterior Cingulate, Nucleus Accumbens, Hippocampus, Amygdala and Dorsolateral Prefrontal Cortex
Conditions Studied
Interventions
- DEVICE Electroconvulsive Therapy
Study Locations (1)
Massachusetts
- Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 102 participants |
| Start Date | 2019-06-28 |
| Est. Completion | 2024-05-31 |
What the finished NCT04059952 record still lists
NCT04059952 is an observational study that tracks outcomes without assigning an intervention. The registered 102 participants enrollment target is mid-sized for trials with a published cap, below the 213-participant average among 29 other Bipolar Depression trials with a reported enrollment target (52% lower).
The record links to 2 conditions, with Bipolar Depression appearing as the primary indexed condition, and to 1 intervention - of which Electroconvulsive Therapy is the first listed.
NCT04059952 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04059952 about?
NCT04059952 is a clinical study titled "Mechanism of Action of Electroconvulsive Therapy". This is an observational neuroimaging study assessing the effects of ECT on the brains of patients with unipolar and bipolar depression.
What is the current status of trial NCT04059952?
This trial is currently completed. The enrollment target is 102 participants. The study started on 2019-06-28. Estimated completion is 2024-05-31.
What conditions does trial NCT04059952 study?
This clinical trial studies the following conditions: Bipolar Depression, Unipolar Depression.
What interventions are being tested in trial NCT04059952?
The interventions under investigation include: Electroconvulsive Therapy (DEVICE).
Who is sponsoring clinical trial NCT04059952?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04059952 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Bipolar Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04059952's enrollment target sits among peer trials
102 14th of 29 higher than 16 of 29 other Bipolar Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Bipolar Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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