Massachusetts General Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).

2,032 total trials 336 currently recruiting 1284 completed early-phase tilt top decile by trial count

Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.

Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.

Top-decile sponsor footprint

Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,032 total, page 18 of 41

COMPLETED NA

Building Resiliency in Patients Admitted to the Neuroscience Intensive Care Unit and Their Caregivers

NCT03694678

TERMINATED Phase 2

Efficacy and Safety of Apixaban in the Treatment of Heparin Induced Thrombocytopenia (HIT)

NCT03594045

TERMINATED NA

Treating Depression in Patients With De Quervain's Tenosynovitis; An Integrated Web Based Skills Intervention

NCT04069741

COMPLETED Phase 1

Probiotics and Oxytocin Nasal Spray on Social Behaviors of Autism Spectrum Disorder (ASD) Children

NCT03337035

TERMINATED NA

Paresthesia Free Spinal Cord Stimulation (PF-SCS)

NCT03670147

COMPLETED Phase 4

Tocilizumab Plus a Short Prednisone Taper for GCA

NCT03726749

COMPLETED Phase 2

Safety and Efficacy of Abatacept in IgG4-Related Disease

NCT03669861

TERMINATED Phase 3

Memantine for the Treatment of Social Deficits in Youth With Disorders of Impaired Social Interactions

NCT03553875

TERMINATED Phase 1

Topical Calcipotriene Treatment for Breast Cancer Immunoprevention

NCT03596073

COMPLETED NA

Using Imaging to Assess Effects of THC on Brain Activity

NCT03655717

COMPLETED NA

The BRIgHT Program: Building Resilience in HIV Together

NCT03673098

COMPLETED Phase 2

EEG Studies of Ketamine General Anesthesia

NCT03553758

COMPLETED

Examining the Association Between Pre-existing Sleep Disturbance and Postoperative Delirium

NCT03498560

COMPLETED Phase 4

Improving Driving in Young People With Autism Spectrum Disorders

NCT03538431

COMPLETED

Williams Syndrome Strength, Hormones, Activity & Adiposity, DNA Programming, Eating Study

NCT03758651

COMPLETED

Assessing Tele-Health Outcomes in Multiyear Extensions of PD Trials

NCT03538262

COMPLETED NA

Rapid Cadence Cycling for Parkinson's Disease: A Study of Implementation and Efficacy in the Community Setting

NCT03675932

COMPLETED NA

Inpatient Palliative Care for Patients Undergoing Hematopoietic Stem Cell Transplantation

NCT03641378

COMPLETED NA

A Randomized Controlled Trial of an Advanced Care Planning Video Decision Support Tool for Patients With End-Stage Liver Disease

NCT03557086

TERMINATED NA

Transcranial Pulse Near-Infrared Light in Generalized Anxiety Disorder: a Placebo-Controlled Study

NCT03420456

COMPLETED

REsting and Stimulus-based Paradigms to Detect Organized NetworkS and Predict Emergence of Consciousness

NCT03504709

COMPLETED NA

Endocrinology Auto-Triggered e-Consults

NCT03542084

COMPLETED Phase 4

Post-Discharge Smoking Cessation Strategies: Helping HAND 4

NCT03603496

COMPLETED NA

Psychological Intervention Mobile App for Patients With AML

NCT03372291

COMPLETED

Validity and Feasibility of the CRSR-FAST

NCT03549572

COMPLETED Phase 2

Ruxolitinib Pre-, During- and Post-HSCT for Patients With Primary or Secondary Myelofibrosis.

NCT03427866

COMPLETED NA

CPI Training for Parents of Children With ASD

NCT03537261

COMPLETED NA

Effect of Modulating Gamma Oscillations Using tACS

NCT03412604

COMPLETED Phase 4

Pilot Study for Zoledronic Acid to Prevent Bone Loss After Bariatric Surgery

NCT03424239

COMPLETED NA

Investigating the Impact of Professional Development Coaching Programs in Residents & Fellows

NCT04883307

COMPLETED NA

Evaluating the Accuracy of an Integrated Vital Sign Measurement Platform

NCT03589716

COMPLETED Phase 1

IDH2 Inhibition Using Enasidenib as Maintenance Therapy for IDH2-mutant Myeloid Neoplasms Following Allogeneic Stem Cell Transplantation

NCT03515512

COMPLETED Phase 2

The Insulin-Only Bionic Pancreas Bridging Study

NCT03565666

COMPLETED NA

The Insulin-Only Bionic Pancreas Bridging Study- Pediatric Transitional Study

NCT04112069

COMPLETED NA

MBCT Delivered Via Group Videoconferencing for ACS Patients With Elevated Depression Symptoms

NCT03878160

COMPLETED NA

Resiliency Training on the College Campus

NCT06038786

COMPLETED

Characterizing the Electroencephalogram Signature of Fentanyl During Induction of General Anesthesia

NCT03866278

COMPLETED NA

A Podcast Mind-Body Program for Military Caregiver

NCT03732183

COMPLETED NA

Early Integrated Telehealth Versus In-Person Palliative Care for Patients With Lung Cancer

NCT03375489

COMPLETED NA

Preliminary Study 2 to Test the Effects of Ambulatory Voice Biofeedback

NCT03416868

COMPLETED NA

Internet-based Conversational Engagement Clinical Trial

NCT02871921

COMPLETED NA

Developing a Positive Psychology Intervention to Promote Health Behaviors in Metabolic Syndrome: Proof-of Concept Trial

NCT03473886

COMPLETED Phase 2

Investigation of Sleep in the Intensive Care Unit

NCT03355053

COMPLETED

Collection of Breath and Sweat to Identify Indicators of Hypoglycemia

NCT03600116

COMPLETED NA

The Role of Cognitive Control in the Transdiagnostic Conceptualization of "Intrusive Thoughts"

NCT03414619

TERMINATED Phase 1

Transcutaneous Vagus Nerve Stimulation for Motor Recovery After Stroke

NCT03292159

COMPLETED

Application of IV 99mTc-tilmanocept for Imaging of Macrophage-specific Inflammation

NCT03523130

COMPLETED NA

Decision-making Impairments in OCD: An Integrated Behavioral Economics Model

NCT03420495

COMPLETED NA

Interprofessional Group Intervention to Promote Faculty Wellbeing and Engagement

NCT04305886

COMPLETED Phase 2

EEG Studies of Sevoflurane-Induced General Anesthesia

NCT03503578

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Phase Distribution

PhaseTrial count
Phase 1 226
Phase 2 289
Phase 3 58
Phase 4 182

What is open in the Massachusetts General Hospital pipeline

336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).

Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).

Top condition: Depression (29 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.