Massachusetts General Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,742 sponsors by registered trial count).
Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.
Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.
Top-decile sponsor footprint
Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
1,284 of 1,487 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
2,032 total, page 16 of 41
To Observe Whether Isoflurane Can Treat COVID-19 Patients
NCT04492943
Efficacy of Tocilizumab on Patients With COVID-19
NCT04356937
Nitric Oxide Inhalation Therapy for COVID-19 Infections in the ED
NCT04338828
Non-Invasive Monitoring of Respiratory Function in Spontaneously Breathing Patients With COVID-19 Infection
NCT04356443
NO Prevention of COVID-19 for Healthcare Providers
NCT04312243
Developing a Down Syndrome Health Instrument
NCT04631237
Outcomes Related to COVID-19 Treated With Hydroxychloroquine Among In-patients With Symptomatic Disease
NCT04332991
The E-health Application To Modify ORal Energy Intake and Measure Outcomes REmotely in ALS Clinical Trial (EAT MORE2)
NCT04051333
Nitric Oxide Gas Inhalation in Severe Acute Respiratory Syndrome in COVID-19
NCT04306393
Nitric Oxide Gas Inhalation Therapy for Mild/Moderate COVID-19
NCT04305457
Online Trial Examining Validity and Reliability of the Shared Decision Making Process Survey
NCT04317690
Online Trial Examining Validity of the Shared Decision Making Process Survey With Video Vignettes
NCT04317274
A Trial of Traffic Light Labeling With Behavioral Nudges and a Healthy Recipe Database to Increase Selection of Healthier Foods in Client-choice Food Pantries
NCT04243252
TMS in Preclinical and Prodromal AD: Modulation of Brain Networks and Memory
NCT04294888
COVID-19 Testing Sample Acquisition Throughput and Efficiency
NCT04532411
Pilot Study of the Haymakers for Hope Fitness Program
NCT04220216
PEERS Using Peer Mentors to Deliver Depression Care
NCT04319094
Immune Monitoring to Facilitate Belatacept Monotherapy
NCT04177095
Heterogeneity Informed Nutrition Therapy for Gestational Diabetes Mellitus
NCT04187521
Telemedicine Abdominal Exams & Imaging
NCT04254588
Inflammation and Cardiovascular Health in Women
NCT04224181
Engagement With an Adaptive Mobile Health Smoking Cessation Intervention
NCT04020718
School-Based Living In Families With Emotions Training
NCT06793878
Evaluation of a Resiliency Intervention for Siblings of Children With Autism Spectrum Disorder (ASD)
NCT04369417
Assessing Efficacy of Intravenous Acetaminophen for Perioperative Pain Treatment in Spinal Surgery
NCT05764707
Effectiveness of an Integrated Treatment to Address Smoking Cessation and Anxiety/ Depression in People Living With HIV
NCT03904186
Relative Sarcopenia and Cardiometabolic Risk in Young Adults With Obesity
NCT04195061
Text-Enabled Ascertainment and Community Linkage for Health
NCT04058301
rTMS as a Treatment for PPA
NCT03406429
Connect for Health Pediatric Weight Management Program
NCT04042493
Electronic Pill Bottle Monitoring to Promote Medication Adherence for People With Multiple Sclerosis
NCT04130256
Investigation of Cannabidiol for Reduction of NeuroInflammation in Chronic Back Pain
NCT03891264
A Pilot of Methylphenidate in Mild Cognitive Impairment and Dementia Participants.
NCT03811847
Effects of Gender-Affirming Hormone Therapy Among Transgender Women
NCT04128488
The Effects of Exercise on Sleep and Brain Health
NCT04210882
Small-group, Virtual Program for Improving Symptoms and Distress Related to Hormonal Therapy for Breast Cancer Survivors
NCT03837496
Auricular Vagus Nerve Stimulation for Chronic Pain
NCT03959111
Executive Function and Symptom Reduction in Youth Receiving Home-based Treatment With Collaborative Problem Solving
NCT04121650
Psychological Intervention For Brain Tumor Caregivers
NCT04109209
Study of the Combination of DKN-01 and Nivolumab in Previously Treated Patients With Advanced Biliary Tract Cancer (BTC)
NCT04057365
A Tailored Program to Promote Well-being and Physical Activity in Mid-life Adults With Low Physical Activity
NCT04745182
HIV Exposure in Utero and Metabolic Disease Risk in HIV-Negative Young Adults
NCT04132830
Early Insertion of Axillary Impella® With VA ECMO
NCT04084015
Impact of a Patient Decision Aid for Treatment of Aortic Stenosis
NCT04103931
Waitlist-Control Trial of Smartphone Cognitive Behavioral Therapy (CBT) for Body Dysmorphic Disorder (BDD)
NCT03673046
Managing Pain and Cognitions in Older Adults With Mild Cognitive Impairment or Memory Related Problems and Chronic Pain
NCT04044183
Aspirin for the Treatment of Nonalcoholic Fatty Liver Disease
NCT04031729
Bone Modeling Effects of Combined Anabolic/Antiresorptive Administration
NCT04026256
Assessing Efficacy of Intravenous Acetaminophen for Perioperative Pain Control for Oocyte Retrieval
NCT03073980
Umbralisib and Rituximab as Initial Therapy for Patients With Follicular Lymphoma and Marginal Zone Lymphoma
NCT03919175
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 226 |
| Phase 2 | 289 |
| Phase 3 | 58 |
| Phase 4 | 182 |
Therapeutic Areas
What is open in the Massachusetts General Hospital pipeline
336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).
Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).
Top condition: Depression (29 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Massachusetts General Hospital: open-pipeline peers nationwide
Peers matched on 2,032 registered trials and 17% open enrollment, not the therapeutic-area sidebar.
Massachusetts General Hospital sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 2,032 trials (± recruiting share)
- National Institute of Allergy and Infectious Diseases (NIAID) · 2,006 trials · 8% recruiting
- Memorial Sloan Kettering Cancer Center · 1,884 trials · 17% recruiting
- Pfizer · 1,845 trials · 6% recruiting
- Stanford University · 1,744 trials · 15% recruiting
Sponsors near 17% open enrollment (± trial volume)
- Rush University Medical Center · 17% recruiting · 320 trials
- OHSU Knight Cancer Institute · 17% recruiting · 211 trials
- Adagene · 17% recruiting · 6 trials
- Agendia · 17% recruiting · 6 trials
Related
What to do with this Massachusetts General Hospital page
2,032 registered trials is a research-attention snapshot, not an endorsement of Massachusetts General Hospital or any single study.
- 336 of Massachusetts General Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Depression is the condition Massachusetts General Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Depression trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Massachusetts General Hospital pipeline card: 2,032 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.