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NCT04580693 · ClinicalTrials.gov registry record
The Impact of Exercise-Induced Cardiac Remodeling on Myocardial Efficiency
A clinical trial of Cardiomyopathy, Hypertrophic, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- 87
- Enrollment target
- 1
- Study location
NCT04580693: Completed study of Cardiomyopathy, Hypertrophic, sponsored by Massachusetts General Hospital.
NCT04580693 is a study of Cardiomyopathy, Hypertrophic that has completed, run by Massachusetts General Hospital. The registered enrollment target is 87 participants, below the 359-participant average among 6 other Cardiomyopathy, Hypertrophic trials with a reported enrollment target (76% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04580693, a study of Cardiomyopathy, Hypertrophic, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- 87 participants
- Enrollment target
- 1
- Study location
Study Summary
This research study is being conducted to find out how heart function and energy use differ among healthy endurance athletes, individuals who do not exercise regularly, and patients with hypertrophic cardiomyopathy. The research study involves taking part in a cardiopulmonary exercise test (CPET), two positron emission tomography (PET) scans, an echocardiogram, and blood draws. The study will consist of a total of three visits scheduled over a maximum of two weeks. By determining how heart function and energy use differ between our three groups of healthy endurance athletes, individuals who do not exercise regularly, and patients with hypertrophic cardiomyopathy, the investigators hope to have this work translate into a novel clinical tool for differentiating pathologic changes of the heart from physiological changes in heart. This is otherwise known as "gray-zone" left ventricular hypertrophy, or enlargement of the left ventricle.
Primary Outcome
The ratio of myocardial oxygen consumption to myocardial work.
Conditions Studied
Interventions
- OTHER PET Scan
Study Locations (1)
Massachusetts
- Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 87 participants |
| Start Date | 2019-02-28 |
| Est. Completion | 2022-06-09 |
What the finished NCT04580693 record still lists
NCT04580693 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 87 participants, a relatively small participant target, below the 359-participant average among 6 other Cardiomyopathy, Hypertrophic trials with a reported enrollment target (76% lower).
The record links to 1 condition, with Cardiomyopathy, Hypertrophic appearing as the primary indexed condition, and to 1 intervention - of which PET Scan is the first listed.
NCT04580693 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04580693 about?
NCT04580693 is a clinical study titled "The Impact of Exercise-Induced Cardiac Remodeling on Myocardial Efficiency". This research study is being conducted to find out how heart function and energy use differ among healthy endurance athletes, individuals who do not exercise regularly, and patients with hypertrophic cardiomyopathy. The research study involves taking part in a cardiopulmonary exercise test (CPET), t...
What is the current status of trial NCT04580693?
This trial is currently completed. The enrollment target is 87 participants. The study started on 2019-02-28. Estimated completion is 2022-06-09.
What conditions does trial NCT04580693 study?
This clinical trial studies the following conditions: Cardiomyopathy, Hypertrophic.
What interventions are being tested in trial NCT04580693?
The interventions under investigation include: PET Scan (OTHER).
Who is sponsoring clinical trial NCT04580693?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04580693 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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