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NCT01590862 · ClinicalTrials.gov registry record · NA
ON/OFF Stimulation and Reward Motivation in Patients With Deep Brain Stimulators
A NA study, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- NA
- Development phase
- 13
- Enrollment target
NCT01590862: Completed NA study, sponsored by Massachusetts General Hospital.
NCT01590862 is a NA study that has completed, run by Massachusetts General Hospital. The registered enrollment target is 13 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01590862, a NA study, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 13 participants
- Enrollment target
Study Summary
We propose to study approach/avoidance behavior as measured by the Approach Avoidance task in 20 epilepsy patients undergoing implementation of depth electrodes for seizure monitoring in the Epilepsy Monitoring Unit at MGH. We will also study the effects of VC/VS electrical stimulation on approach-avoidance conflict in 20 adult patients who have undergone DBS implantation for severe MDD and/or OCD. There are 100-200 patients in the world with DBS electrodes in the VC/VS, and our research team cares for more than any other institution. Both participant groups will be assessed with respect to reward-aversion decision conflict using the task. The task will be performed with concurrent EEG recordings in DBS patients, and with continuous recording through our invasive neurophysiology rig in EMU subjects.
Primary Outcome
The Approach Avoidance task is a computer task that assesses approach avoidance behavior. We will assess whether stimulation of the Ventral Capsule/Ventral Striatum has an effect on behavior by executing this task with the DBS system on and off.
Interventions
- DEVICE Deep Brain Stimulator
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 13 participants |
| Start Date | 2021-01-23 |
| Est. Completion | 2026-03-31 |
| Phase | NA |
What the finished NCT01590862 record still lists
NCT01590862 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 13 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Deep Brain Stimulator is the first listed.
NCT01590862 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01590862 about?
NCT01590862 is a clinical study titled "ON/OFF Stimulation and Reward Motivation in Patients With Deep Brain Stimulators". We propose to study approach/avoidance behavior as measured by the Approach Avoidance task in 20 epilepsy patients undergoing implementation of depth electrodes for seizure monitoring in the Epilepsy Monitoring Unit at MGH. We will also study the effects of VC/VS electrical stimulation on approach-a...
What is the current status of trial NCT01590862?
This trial is currently completed. It is a NA study. The enrollment target is 13 participants. The study started on 2021-01-23. Estimated completion is 2026-03-31.
What interventions are being tested in trial NCT01590862?
The interventions under investigation include: Deep Brain Stimulator (DEVICE).
Who is sponsoring clinical trial NCT01590862?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01590862's enrollment target sits among peer trials
13 1911th of 2000 higher than 88 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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