Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04244162 · ClinicalTrials.gov registry record
Postoperative Neurocognitive Disorders
A clinical trial of Obstructive Sleep Apnea and Neurocognitive Disorders, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- 32
- Enrollment target
- 1
- Study location
NCT04244162: Completed study of Obstructive Sleep Apnea and Neurocognitive Disorders, sponsored by Massachusetts General Hospital.
NCT04244162 is a study of Obstructive Sleep Apnea and Neurocognitive Disorders that has completed, run by Massachusetts General Hospital. The registered enrollment target is 32 participants, below the 221-participant average among 155 other Obstructive Sleep Apnea trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04244162, a study of Obstructive Sleep Apnea and Neurocognitive Disorders, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- 32 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to examine the mechanisms of brain injury contributing to postoperative neurocognitive disorders (PNCD) in an at-risk population (obstructive sleep apnea (OSA)) undergoing surgery. The investigators will enroll 50 OSA patients scheduled for surgery. All patients will have a brain scan (fMRI) within five days before surgery and two days and six months after surgery. During this visit cognitive function will be assessed using the Wide Range Assessment of Memory and Learning (WRAML2) and Montreal Cognitive Assessment (MoCA) tests. Patients will also be asked to participate in a blood draw during the first 2 visits for fMRI (within five days of surgery and two days after surgery). The Confusion Assessment Method (CAM-S) test, will be used to examine postoperative delirium.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Brain Imaging
- DIAGNOSTIC_TEST Cognitive testing
- DIAGNOSTIC_TEST Blood Biomarkers
Study Locations (1)
California
- Ronald Reagan UCLA Medical Center, Department of Anesthesiology & Perioperative Medicine - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2020-12-12 |
| Est. Completion | 2025-08-31 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04244162
The ClinicalTrials.gov registry entry for NCT04244162 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 32 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 221-participant average among 155 other Obstructive Sleep Apnea trials with a reported enrollment target (86% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Obstructive Sleep Apnea appearing as the primary indexed condition, and to 3 interventions - of which Brain Imaging is the first listed.
NCT04244162 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT04244162 about?
NCT04244162 is a clinical study titled "Postoperative Neurocognitive Disorders". The purpose of this study is to examine the mechanisms of brain injury contributing to postoperative neurocognitive disorders (PNCD) in an at-risk population (obstructive sleep apnea (OSA)) undergoing surgery. The investigators will enroll 50 OSA patients scheduled for surgery. All patients will hav...
What is the current status of trial NCT04244162?
This trial is currently completed. The enrollment target is 32 participants. The study started on 2020-12-12. Estimated completion is 2025-08-31.
What conditions does trial NCT04244162 study?
This clinical trial studies the following conditions: Obstructive Sleep Apnea, Neurocognitive Disorders.
What interventions are being tested in trial NCT04244162?
The interventions under investigation include: Brain Imaging (DIAGNOSTIC_TEST), Cognitive testing (DIAGNOSTIC_TEST), Blood Biomarkers (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT04244162?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04244162 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obstructive Sleep Apnea
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)
RECRUITING · NA
-
Intermittent Hypoxia-initiated Plasticity in Humans: A Multi-pronged Therapeutic Approach to Treat Sleep Apnea and Overlapping Co-morbidities
RECRUITING · Phase 1
-
Effect of CPAP on Blood Pressure in Excessively Sleepy Obstructive Sleep Apnea Subtype
RECRUITING
-
Cognition After OSA Treatment Among Native American People (CATNAP)
RECRUITING · NA
-
Patient-centered and Neurocognitive Outcomes with Acetazolamide for Sleep Apnea
RECRUITING · Phase 2
-
Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS)
RECRUITING · NA
Explore more on PlainTrial
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.