GlaxoSmithKline

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, GlaxoSmithKline sits in the top decile of US sponsors by registered trial count (#17 of 15,742 sponsors by registered trial count).

1,345 total trials 50 currently recruiting 1130 completed early-phase tilt top decile by trial count

GlaxoSmithKline: 1,345 sponsored US clinical trials, 50 recruiting.

GlaxoSmithKline sponsors 1,345 registered US clinical trials on ClinicalTrials.gov, 50 of them currently recruiting, and 1,130 completed. 486 of these trials are in Phase 3-4 (later-stage) and 791 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Pulmonary Disease, Chronic Obstructive, with 30 trials.

Top-decile sponsor footprint

GlaxoSmithKline ranks in the top decile of sponsors by registered trial count (#17 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 66/100

1,130 of 1,249 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (90.5%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,345 total, page 24 of 27

COMPLETED Phase 1

fMRI Study Comparing BOLD Activation Patterns Using GW679769 In Subjects With Social Anxiety Disorder

NCT00332046

COMPLETED Phase 2

Effects Of GW679769 On Sleep Onset And Maintenance,And Next Day Functioning In The Elderly And Non-elderly With Primary Insomnia

NCT00280436

TERMINATED Phase 2

Effects Of GW679769 On Bladder Nerve Function And Symptoms Of Overactive Bladder In Spinal Cord Injury Patients

NCT00332319

COMPLETED Phase 1

Observational Study Evaluating The Processing Or Breakdown Of GW679769 In Subjects With Hepatic Impairment

NCT00359177

COMPLETED Phase 3

Retigabine Efficacy and Safety Trial for Partial Onset Refractory Seizures in Epilepsy

NCT00235755

COMPLETED Phase 2

A Study Of GW679769 Compared To Placebo In Women With Overactive Bladder

NCT00321477

COMPLETED

Evaluation of COPD (Chronic Obstructive Pulmonary Disease) to Longitudinally Identify Predictive Surrogate Endpoints

NCT00292552

TERMINATED

Effect Of GW501516X On How The Heart Obtains And Uses Energy

NCT00318617

COMPLETED Phase 1

To Examine The Effects Of Lapatinib On Orally And Intravenously Administered Midazolam In Cancer Patients

NCT00258050

COMPLETED Phase 3

Open-Label Extension of a Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Lovaza® and Simvastatin Therapy in Hypertriglyceridemic Subjects

NCT00903409

COMPLETED Phase 3

Converting From Ropinirole Immediate Release (IR) To Ropinirole Controlled-Release for RLS (Restless Legs Syndrome)

NCT00256854

COMPLETED

Observational Study Of An Electronic Questionnaire In Patients With Chronic Obstructive Pulmonary Disease (COPD)

NCT00259909

COMPLETED Phase 2

Antifibrotic Activity Of GI262570 In Chronic Hepatitis C Subjects

NCT00244751

COMPLETED Phase 2

Effects Of Lapatinib (GW572016) In Patients With Relapsed Adenocarcinoma Of The Esophagus

NCT00259987

COMPLETED Phase 2

Use Of SB424323 With Aspirin In Non-Valvular Atrial Fibrillation In Patients At A Low Or Intermediate Risk For Stroke

NCT00240643

COMPLETED Phase 2

SB-480848 In Subjects With Coronary Heart Disease

NCT00269048

COMPLETED Phase 3

Lapatinib In Combination With Trastuzumab Versus Lapatinib Monotherapy In Subjects With HER2-positive Metastatic Breast Cancer

NCT00320385

COMPLETED Phase 3

Study Of Treximet, Formerly Known as Trexima, In The Acute Treatment Of Multiple Migraine Attacks

NCT00240617

COMPLETED Phase 2

GW786034 In Subjects With Locally Recurrent Or Metastatic Clear Cell Renal Cell Carcinoma

NCT00244764

COMPLETED Phase 2

Intravenous Weekly Topotecan In Subjects With Recurrent Or Persistent Endometrial Cancer

NCT00267488

COMPLETED Phase 3

Treximet (Sumatriptan/Naproxen Sodium), Formerly Known as Trexima, In The Acute Treatment Of Multiple Migraine Attacks

NCT00240630

COMPLETED Phase 3

Long-Term Safety Of Ropinirole XR In Patients With Restless Legs Syndrome

NCT00355641

COMPLETED Phase 3

Study Comparing the Immune Response of Fluarix and Fluzone Influenza Vaccines

NCT00197288

COMPLETED Phase 3

Patients With Epilepsy Taking LAMICTAL Immediate-Release Who Switch To Extended-Release Formulation And Vice Versa

NCT00264615

COMPLETED Phase 3

Retigabine (Adjunctive Therapy) Efficacy and Safety Study for Partial Onset Refractory Seizures in Epilepsy

NCT00232596

COMPLETED Phase 4

Study Of Patients With Allergic Rhinitis And Asthma

NCT00296530

COMPLETED Phase 4

Study Of Allergic Rhinitis In Patients Who Also Have Asthma

NCT00296491

COMPLETED Phase 2

SB-773812 Administered In Adults With Schizophrenia

NCT00259870

COMPLETED Phase 2

Odiparcil For The Prevention Of Venous Thromboembolism

NCT00244725

COMPLETED Phase 2

Study In People With Type 2 Diabetes

NCT00196989

COMPLETED Phase 3

A Study In Patients With Type 2 Diabetes Mellitus

NCT00256867

TERMINATED Phase 1

Cyclophosphamide Drug Interaction Study In Cancer Patients

NCT00334646

COMPLETED Phase 3

Once-Daily Investigational Nasal Spray In Adults And Adolescents With Seasonal Allergic Rhinitis (SAR)

NCT00197262

COMPLETED Phase 4

A Study To Assess The Quality Of Bone In Patients Taking Oral Ibandronate Versus Placebo

NCT02948881

COMPLETED Phase 2

A Study Of A New Medicine (GW679769) For The Treatment Of Social Anxiety Disorder

NCT00273039

COMPLETED Phase 3

Study Of Adults And Adolescents With Vasomotor Rhinitis

NCT00117325

COMPLETED Phase 3

Once-Daily Investigational Nasal Spray In Adults And Adolescents With Vasomotor Rhinitis

NCT00118703

COMPLETED Phase 4

Abacavir/Lamivudine Versus Emtricitabine/Tenofovir Both In Combination With Lopinavir/Ritonavir For The Treatment Of HIV

NCT00244712

TERMINATED Phase 3

COREG MR Versus TOPROL-XL On Reduction Of Microalbuminuria In Patients With Hypertension And Microalbuminuria

NCT00123903

TERMINATED Phase 3

Study Of Chemokine Coreceptor 5 (CCR5) Antagonist GW873140 In R5/X4-Tropic Treatment-Experienced HIV-Infected Subjects

NCT00197197

TERMINATED

Observational Study of HIV-Infected Subjects With X4-Tropic or Non-Phenotypeable Virus

NCT00321438

COMPLETED Phase 1

Ropinirole Tablets In Young Patients With Restless Legs Syndrome

NCT00140712

COMPLETED Phase 2

First-line Treatment Of Subjects With Extensive Disease Small Cell Lung Cancer With Weekly Hycamtin And Paraplatin

NCT00316186

COMPLETED Phase 3

COX-2 Inhibitor Study In Patients With Rheumatoid Arthritis

NCT00113308

COMPLETED Phase 3

Ropinirole XR (Extended Release) In Patients With Restless Legs Syndrome

NCT00197080

TERMINATED Phase 3

Screening Protocol To Determine Eligibility For Studies Of The Chemokine Coreceptor 5 (CCR5) Antagonist GW873140

NCT00123890

COMPLETED Phase 2

A New Oral Treatment For Type II Diabetes Mellitus

NCT00111800

COMPLETED Phase 2

Study Of Lapatinib In Combination With Paclitaxel In The Treatment Of Newly Diagnosed Inflammatory Breast Cancer

NCT00111787

COMPLETED Phase 2

SB497115 (Oral Thrombopoietin Receptor Agonist) Versus Placebo In Adults With Thrombocytopenia Due To Hepatitis C

NCT00110799

COMPLETED Phase 3

Study In Adolescent And Adult Subjects 12 Years Of Age And Older With Seasonal Allergic Rhinitis To Assess Onset of Action

NCT00118729

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Phase Distribution

PhaseTrial count
Phase 1 440
Phase 2 351
Phase 3 377
Phase 4 109

What is open in the GlaxoSmithKline pipeline

50 recruiting of 1,345 indexed (4% open); 1,130 completed (84%).

Phase mix: 486 late (III/IV) vs 791 early (I/II) (early-phase heavy).

Top condition: Pulmonary Disease, Chronic Obstructive (30 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

GlaxoSmithKline: open-pipeline peers nationwide

Peers matched on 1,345 registered trials and 4% open enrollment, not the therapeutic-area sidebar.

GlaxoSmithKline sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 0%5%10%15% Total trials Recruiting share GlaxoSmithKlineEli Lilly and CompanyUniversity of MichiganNovartis PharmaceuticalsAstraZenecaStryker OrthopaedicsUS Oncology ResearchOtsuka Pharmaceutical Development & CommercializationTeva Branded Pharmaceutical Products R&D
GlaxoSmithKline sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

GlaxoSmithKline sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,345 trials (± recruiting share)

Sponsors near 4% open enrollment (± trial volume)

What to do with this GlaxoSmithKline page

1,345 registered trials is a research-attention snapshot, not an endorsement of GlaxoSmithKline or any single study.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. GlaxoSmithKline pipeline card: 1,345 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.