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NCT00123903 · ClinicalTrials.gov registry record · Phase 3

COREG MR Versus TOPROL-XL On Reduction Of Microalbuminuria In Patients With Hypertension And Microalbuminuria

A Phase 3 study, sponsored by GlaxoSmithKline.

Terminated
Registry status
Phase 3
Development phase
1,220
Enrollment target

NCT00123903: Clinical Trial Phase 3 study, sponsored by GlaxoSmithKline.

NCT00123903 is a Phase 3 study that was terminated before completion, run by GlaxoSmithKline. The registered enrollment target is 1,220 participants, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (58% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00123903, a Phase 3 study, was terminated before completion, sponsored by GlaxoSmithKline.

TERMINATED
Registry status
Phase 3
Development phase
1,220 participants
Enrollment target

Study Summary

This study was designed to determine whether COREG MR is more effective than TOPROL-XL in reducing microalbuminuria in type 2 diabetic or non-diabetic patients with high blood pressure and microalbuminuria.

Interventions

  • DRUG lisinopril
  • DRUG carvedilol MR
  • DRUG metoprolol xl

Trial Details

FieldValue
Enrollment Target 1,220 participants
Start Date 2005-07
Est. Completion 2006-05
Phase Phase 3
GlaxoSmithKline

1,345 total trials

Why NCT00123903 stopped before completion

NCT00123903 is an interventional study that assigns participants to a tested intervention. Its 1,220 participants enrollment target places it among the larger protocols in the corpus, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (58% higher).

The record links to 0 conditions, and to 3 interventions - of which lisinopril is the first listed.

NCT00123903 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00123903 about?

NCT00123903 is a clinical study titled "COREG MR Versus TOPROL-XL On Reduction Of Microalbuminuria In Patients With Hypertension And Microalbuminuria". This study was designed to determine whether COREG MR is more effective than TOPROL-XL in reducing microalbuminuria in type 2 diabetic or non-diabetic patients with high blood pressure and microalbuminuria.

What is the current status of trial NCT00123903?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 1,220 participants. The study started on 2005-07. Estimated completion is 2006-05.

What interventions are being tested in trial NCT00123903?

The interventions under investigation include: lisinopril (DRUG), carvedilol MR (DRUG), metoprolol xl (DRUG).

Who is sponsoring clinical trial NCT00123903?

This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00123903's enrollment target sits among peer trials

1,220 214th of 2000 higher than 1,786 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00123903, the US trial registry maintained by the National Library of Medicine. NCT00123903 (large enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.