Columbia University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Columbia University sits in the top decile of US sponsors by registered trial count (#34 of 15,742 sponsors by registered trial count).

958 total trials 171 currently recruiting 597 completed early-phase tilt top decile by trial count

Columbia University: 958 sponsored US clinical trials, 171 recruiting.

Columbia University sponsors 958 registered US clinical trials on ClinicalTrials.gov, 171 of them currently recruiting, and 597 completed. 88 of these trials are in Phase 3-4 (later-stage) and 191 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 9 trials.

Top-decile sponsor footprint

Columbia University ranks in the top decile of sponsors by registered trial count (#34 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 42/100

597 of 736 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

958 total, page 8 of 20

COMPLETED NA

Postpartum Oxytocin Administration in the Era of Delayed Cord Clamping

NCT04632264

TERMINATED NA

RNA Precision Oncology in Advanced Pancreatic Cancer

NCT04476537

COMPLETED NA

The Care After Life-threatening Medical Events Study

NCT04589559

COMPLETED NA

Telehealth After Stroke Care: Integrated Multidisciplinary Access to Post-stroke Care

NCT04640519

COMPLETED NA

Cerebrospinal Fluid Biomarkers in Bariatric Surgery

NCT04350892

COMPLETED NA

Smoking Cessation Pilot for People Living With HIV (PLWH)

NCT04808609

TERMINATED Early Phase 1

IV Contrast-Enhanced Cone Beam Computed Tomography (CBCT) in Radiotherapy

NCT04199754

COMPLETED Phase 2

Daily Vitamin D for Sickle-cell Respiratory Complications

NCT04170348

COMPLETED

Practical Approaches to Care in Emergency Syncope

NCT04533425

COMPLETED

Technology Development for Noninvasive Prenatal Genetic Diagnosis Using Whole Fetal Cells From Maternal Peripheral Blood

NCT04285814

COMPLETED NA

Doppler Ultrasound Compared With Stethoscope to Assess Heart Rate (HR)

NCT04242654

COMPLETED NA

Non-invasive Blood-brain Barrier Opening in Alzheimer's Disease Patients Using Focused Ultrasound

NCT04118764

COMPLETED NA

(CONCERN) Clinical Decision Support (CDS) System

NCT03911687

TERMINATED Phase 2

Study for the Use of the IL-6 Inhibitor Clazakizumab in Patients With Life-threatening COVID-19 Infection

NCT04381052

COMPLETED NA

SUNLIGHT Study: Online Support Groups for MS to Address COVID-19

NCT04379661

COMPLETED Phase 4

Intermediate or Prophylactic-Dose Anticoagulation for Venous or Arterial Thromboembolism in Severe COVID-19

NCT04367831

COMPLETED

Pediatrics HOT COVID-19 Database in NY Tristate

NCT04445402

COMPLETED NA

Well-being Promotion and Sleep Hygiene Education to Improve Sleep Quality

NCT04316663

TERMINATED Phase 2

Saved From COVID-19 - Chloroquine (CQ) Prophylaxis for Health Care Workers at Risk for COVID

NCT04349371

COMPLETED

Awake Proning in COVID-19 Patients With Hypoxemic Respiratory Failure

NCT04408222

TERMINATED Phase 2

Anti-Interleukin-8 (Anti-IL-8) for Patients With COVID-19

NCT04347226

COMPLETED NA

Social Activity, Loneliness and Stigma During COVID-19 Outbreak

NCT04734171

TERMINATED Phase 2

Hydroxychloroquine Post Exposure Prophylaxis for Coronavirus Disease (COVID-19)

NCT04318444

COMPLETED

Acquiring Convalescent Specimens for COVID-19 Antibodies

NCT04342195

COMPLETED NA

Prebiotic vs Probiotic in Multiple Sclerosis

NCT04038541

TERMINATED Phase 4

Amantadine in Treating Cognitive & Motor Impairments in Adolescents and Adults With Cerebral Palsy

NCT04273737

COMPLETED Early Phase 1

Non-fucosylated Anti-CTLA-4 (BMS-986218) + Degarelix Acetate vs. Degarelix Acetate Alone in Men With High-risk Localized Prostate Cancer

NCT04301414

TERMINATED Phase 1

Study of Combination Therapy With the MEK Inhibitor, Cobimetinib, Immune Checkpoint Blockade, Atezolizumab, and the AUTOphagy Inhibitor, Hydroxychloroquine in KRAS-mutated Advanced Malignancies

NCT04214418

TERMINATED NA

Weekly Antepartum Testing in Women With BMI 30-40 and Neonatal Outcomes

NCT04180566

TERMINATED

Circulating Tumor DNA Alterations in Non-small Cell Lung Cancer Patients Treated With Pembrolizumab

NCT04791215

COMPLETED NA

An Anesthesia-Centered Bundle to Reduce Postoperative Pulmonary Complications: The PRIME-AIR Study

NCT04108130

COMPLETED NA

BabyQ's: Randomized Controlled Trial of Health Messaging in Pregnancy and Infancy

NCT04238585

COMPLETED NA

Family-Based Intervention Study of the Effects of Environmental Exposures on Breast Tissue Composition

NCT04265547

TERMINATED Phase 1

Itacitinib and Tocilizumab for Steroid Refractory Acute Graft Versus Host Disease

NCT04070781

COMPLETED NA

Dynamically Tailored Behavioral Interventions in Diabetes

NCT04226027

COMPLETED NA

Smartphone App for Cancer Medication Adherence

NCT05225090

COMPLETED NA

Preventing Drug Abuse Among Sexual Minority Youth

NCT03954535

COMPLETED NA

Ataxia and Exercise Disease Using MRI and Gait Analysis

NCT03701776

COMPLETED NA

Survey of Correction Officers Before and After a Targeted Education Campaign

NCT05451225

COMPLETED NA

Clinical Interviews With Detainees With Early Psychosis

NCT03962348

TERMINATED NA

Clinical Interventions to Mitigate Neurodevelopmental Risk

NCT04233489

COMPLETED NA

Cognitive Multi-Tasking Training in Healthy Older Adults

NCT04195230

COMPLETED

Skeletal Fragility in Type 1 Diabetes: Glycemic Control and Bone Strength

NCT04289727

COMPLETED NA

Art Therapy Pain Management Adolescents Pediatric ED

NCT03755687

COMPLETED

Wearable Technology to Assess Gait Function in SMA and DMD

NCT04193085

COMPLETED

Glucose Monitoring During Chemotherapy

NCT04473378

COMPLETED NA

The Effect of Maternal Scent on Sleep Wake States

NCT04301453

COMPLETED NA

AI Mobile Application Versus HCP for Bodyweight Squats

NCT04624594

COMPLETED Phase 2

Inulin for Infections in the Intensive Care Unit

NCT03865706

COMPLETED NA

Information Visualizations to Facilitate HIV-related Patient-provider Communication in New York City (Info Viz: HIV-NYC)

NCT04102540

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Phase Distribution

PhaseTrial count
Phase 1 86
Phase 2 105
Phase 3 23
Phase 4 65

What is open in the Columbia University pipeline

171 recruiting of 958 indexed (18% open); 597 completed (62%).

Phase mix: 88 late (III/IV) vs 191 early (I/II) (early-phase heavy).

Top condition: Obesity (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Columbia University: open-pipeline peers nationwide

Peers matched on 958 registered trials and 18% open enrollment, not the therapeutic-area sidebar.

Columbia University sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 5%10%15%20% Total trials Recruiting share Columbia UniversityUniversity of MinnesotaBrigham and Women's HospitalHoffmann-La RocheUniversity of California, Los AngelesKite, A Gilead CompanyMirum PharmaceuticalsWest Virginia UniversityHospital for Special Surgery, New York
Columbia University sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Columbia University sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 958 trials (± recruiting share)

Sponsors near 18% open enrollment (± trial volume)

What to do with this Columbia University page

958 registered trials is a research-attention snapshot, not an endorsement of Columbia University or any single study.

  • 171 of Columbia University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Obesity is the condition Columbia University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Columbia University pipeline card: 958 registered trials from official public datasets.Report a data error.