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NCT04301414 · ClinicalTrials.gov registry record · Early Phase 1

Non-fucosylated Anti-CTLA-4 (BMS-986218) + Degarelix Acetate vs. Degarelix Acetate Alone in Men With High-risk Localized Prostate Cancer

A Early Phase 1 study, sponsored by Columbia University.

Completed
Registry status
Early Phase 1
Development phase
26
Enrollment target

NCT04301414 is a Early Phase 1 study that has completed, run by Columbia University. The registered enrollment target is 26 participants.

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The verdict

NCT04301414, a Early Phase 1 study, has completed, sponsored by Columbia University.

COMPLETED
Registry status
Early Phase 1
Development phase
26 participants
Enrollment target

Study Summary

The purpose of this study is to see whether immunotherapy with BMS-986218 added to degarelix (which suppresses testosterone) given prior to surgery can decrease the chance that cancer will come back compared to degarelix alone. People who usually have this type of prostate cancer usually do not receive any additional therapy prior to surgery. Approximately 24 individuals will be asked to participate in this study.

Interventions

  • DRUG Degarelix
  • DRUG BMS-986218 and Degarelix

Trial Details

FieldValue
Enrollment Target 26 participants
Start Date 2020-02-25
Est. Completion 2025-03-13
Phase Early Phase 1

Sponsor

Columbia University

958 total trials

What the Registry Record Tells You About NCT04301414

The ClinicalTrials.gov registry entry for NCT04301414 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 26 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Columbia University, which has 958 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Degarelix is the first listed.

NCT04301414 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04301414 about?

NCT04301414 is a clinical study titled "Non-fucosylated Anti-CTLA-4 (BMS-986218) + Degarelix Acetate vs. Degarelix Acetate Alone in Men With High-risk Localized Prostate Cancer". The purpose of this study is to see whether immunotherapy with BMS-986218 added to degarelix (which suppresses testosterone) given prior to surgery can decrease the chance that cancer will come back compared to degarelix alone. People who usually have this type of prostate cancer usually do not rece...

What is the current status of trial NCT04301414?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 26 participants. The study started on 2020-02-25. Estimated completion is 2025-03-13.

What interventions are being tested in trial NCT04301414?

The interventions under investigation include: Degarelix (DRUG), BMS-986218 and Degarelix (DRUG).

Who is sponsoring clinical trial NCT04301414?

This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.