Barbara Ann Karmanos Cancer Institute

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Barbara Ann Karmanos Cancer Institute sits in the top decile of US sponsors by registered trial count (#202 of 15,742 sponsors by registered trial count).

139 total trials 16 currently recruiting 100 completed early-phase tilt top decile by trial count

Barbara Ann Karmanos Cancer Institute: 139 sponsored US clinical trials, 16 recruiting.

Barbara Ann Karmanos Cancer Institute sponsors 139 registered US clinical trials on ClinicalTrials.gov, 16 of them currently recruiting, and 100 completed. 1 of these trials are in Phase 3-4 (later-stage) and 99 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Prostate Cancer, with 4 trials.

Top-decile sponsor footprint

Barbara Ann Karmanos Cancer Institute ranks in the top decile of sponsors by registered trial count (#202 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 48/100

100 of 120 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (83.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

139 total, page 3 of 3

COMPLETED Phase 1

Combination Chemotherapy Followed By Autologous Stem Cell Transplant, and White Blood Cell Infusions in Treating Patients With Non-Hodgkin's Lymphoma

NCT00244946

COMPLETED Phase 2

Gemcitabine Hydrochloride and Genistein in Treating Women With Stage IV Breast Cancer

NCT00244933

COMPLETED Phase 2

Ph II Long Term/Low Dose Xeloda in Head and Neck Squamous Cell Carcinoma After Surgery, Radiation & or Chemo

NCT00258310

COMPLETED Phase 2

Capecitabine and Docetaxel in Treating Patients With Metastatic Prostate Cancer

NCT00258284

COMPLETED Phase 2

Zileuton in Preventing Lung Cancer in Patients With Bronchial Dysplasia

NCT00056004

COMPLETED Phase 1

Imatinib Mesylate and 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Chronic Myelogenous Leukemia

NCT00066326

COMPLETED Phase 2

Gefitinib and Celecoxib in Treating Patients With Refractory Non-Small Cell Lung Cancer

NCT00068653

COMPLETED Phase 2

Isoflavones and Radiation Therapy in Treating Patients With Localized Prostate Cancer

NCT00243048

COMPLETED Phase 2

Imatinib Mesylate After Irinotecan and Cisplatin in Treating Patients With Extensive-Stage Small Cell Lung Cancer

NCT00248482

COMPLETED Phase 2

Celecoxib, Capecitabine, and Irinotecan in Treating Patients With Recurrent or Metastatic Colorectal Cancer

NCT00258232

COMPLETED Phase 1

XK469 in Treating Patients With Advanced Solid Tumors

NCT00028548

COMPLETED Phase 2

Soy Isoflavones in Treating Patients Who Are Undergoing Radical Prostatectomy for Stage I or Stage II Adenocarcinoma of the Prostate

NCT00078923

COMPLETED Phase 2

Celecoxib and Docetaxel in Treating Patients With Non-Small Cell Lung Cancer

NCT00030407

COMPLETED Phase 1

Biological Therapy in Treating Women With Stage IV Breast Cancer

NCT00027807

COMPLETED Phase 2

Celecoxib and Docetaxel in Treating Patients With Advanced Non-Small Cell Lung Cancer

NCT00030420

COMPLETED

Proteases in Patients With Prostate Cancer That Has Spread to the Bone

NCT00899665

COMPLETED Phase 1

Flavopiridol and Docetaxel in Treating Patients With Advanced Solid Tumors

NCT00016185

COMPLETED Phase 2

PEG-Interferon Alfa-2b and Thalidomide in Treating Patients With Recurrent or Metastatic Melanoma

NCT00238329

COMPLETED Phase 2

Chemotherapy in Treating Patients With Advanced Kidney Cancer

NCT00011973

COMPLETED Phase 2

Rebeccamycin Analog in Treating Patients With Advanced Kidney Cancer

NCT00005027

COMPLETED Phase 1

Bryostatin 1 Plus Gemcitabine in Treating Patients With Advanced Cancer

NCT00004144

COMPLETED Phase 2

Bryostatin 1 in Treating Patients With Recurrent or Refractory Hodgkin's Disease

NCT00003936

COMPLETED Phase 2

Combination Chemotherapy in Treating Patients With Stage III or Stage IV Pancreatic Cancer That Cannot Be Removed by Surgery

NCT00004003

COMPLETED Phase 2

Dolastatin 10 in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Previous Hormone Therapy

NCT00003626

COMPLETED Phase 2

Chemotherapy and Vaccine Therapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation and Interleukin-2 in Treating Patients With Recurrent or Refractory Brain Cancer

NCT00014573

COMPLETED Phase 2

Bryostatin 1 in Treating Patients With Myelodysplastic Syndrome

NCT00003171

COMPLETED Phase 1

Combination Chemotherapy In Treating Patients With Advanced Cancer

NCT00003925

COMPLETED Phase 1

Fenretinide in Treating Patients With Solid Tumors

NCT00003250

COMPLETED Phase 1

Bryostatin 1 Plus Cladribine in Treating Patients With Relapsed Chronic Lymphocytic Leukemia

NCT00003174

COMPLETED Phase 2

Bryostatin 1 in Treating Patients With Metastatic Colorectal Cancer

NCT00003220

COMPLETED Phase 2

Biological Therapy Following Surgery and Radiation Therapy in Treating Patients With Primary or Recurrent Astrocytoma or Oligodendroglioma

NCT00004024

COMPLETED Phase 2

Biological Therapy Following Surgery in Treating Patients With Stage III or Stage IV Melanoma

NCT00004022

COMPLETED Phase 1

KRN5500 in Treating Patients With Metastatic Solid Tumors

NCT00002923

COMPLETED Phase 2

Bryostatin 1 in Treating Patients With Relapsed Multiple Myeloma

NCT00002907

COMPLETED Phase 2

Bryostatin 1 in Treating Patients With Relapsed Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia

NCT00002908

COMPLETED Phase 2

Pyrazoloacridine in Treating Patients With Advanced Non-small Cell Lung Cancer

NCT00002656

COMPLETED Phase 2

Pyrazoloacridine in Treating Women With Metastatic Breast Cancer

NCT00002585

COMPLETED Phase 2

Chemotherapy Plus Bone Marrow Transplantation in Treating Patients With Refractory Non-Hodgkin's Lymphoma, Hodgkin's Disease, or Multiple Myeloma

NCT00002552

COMPLETED Phase 2

Chemotherapy and Bone Marrow Transplantation in Treating Patients Acute Myeloid With Leukemia or Myelodysplastic Syndrome

NCT00002547

← Previous Page 3 of 3

What is open in the Barbara Ann Karmanos Cancer Institute pipeline

16 recruiting of 139 indexed (12% open); 100 completed (72%).

Phase mix: 1 late (III/IV) vs 99 early (I/II) (early-phase heavy).

Top condition: Prostate Cancer (4 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Barbara Ann Karmanos Cancer Institute: open-pipeline peers nationwide

Peers matched on 139 registered trials and 12% open enrollment, not the therapeutic-area sidebar.

Barbara Ann Karmanos Cancer Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 050100150 0%10%20%30% Total trials Recruiting share Barbara Ann Karmanos Cancer InstituteCenters for Disease Control and PreventionMclean HospitalShirley Ryan AbilityLabSidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityAbbott Diabetes CareMedtronic VascularMidwest Center for Metabolic and Cardiovascular ResearchVA Connecticut Healthcare System
Barbara Ann Karmanos Cancer Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Barbara Ann Karmanos Cancer Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 139 trials (± recruiting share)

Sponsors near 12% open enrollment (± trial volume)

What to do with this Barbara Ann Karmanos Cancer Institute page

139 registered trials is a research-attention snapshot, not an endorsement of Barbara Ann Karmanos Cancer Institute or any single study.

  • 16 of Barbara Ann Karmanos Cancer Institute's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Prostate Cancer is the condition Barbara Ann Karmanos Cancer Institute studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Prostate Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Barbara Ann Karmanos Cancer Institute pipeline card: 139 registered trials from official public datasets.Report a data error.