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NCT00002547 · ClinicalTrials.gov registry record · Phase 2

Chemotherapy and Bone Marrow Transplantation in Treating Patients Acute Myeloid With Leukemia or Myelodysplastic Syndrome

A Phase 2 study, sponsored by Barbara Ann Karmanos Cancer Institute.

Completed
Registry status
Phase 2
Development phase
280
Enrollment target

NCT00002547: Completed Phase 2 study, sponsored by Barbara Ann Karmanos Cancer Institute.

NCT00002547 is a Phase 2 study that has completed, run by Barbara Ann Karmanos Cancer Institute. The registered enrollment target is 280 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (111% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00002547, a Phase 2 study, has completed, sponsored by Barbara Ann Karmanos Cancer Institute.

COMPLETED
Registry status
Phase 2
Development phase
280 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with bone marrow transplantation may allow the doctor to give higher doses of chemotherapy and kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of bone marrow transplantation following combination chemotherapy in treating patients with acute myeloid leukemia or myelodysplastic syndrome .

Interventions

  • DRUG cyclophosphamide
  • DRUG methotrexate
  • DRUG cytarabine
  • DRUG busulfan
  • DRUG cyclosporine

Trial Details

FieldValue
Enrollment Target 280 participants
Start Date 1987-08
Est. Completion 2003-10
Phase Phase 2

What the finished NCT00002547 record still lists

NCT00002547 is an interventional study that assigns participants to a tested intervention. The registered 280 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (111% higher).

The record links to 0 conditions, and to 5 interventions - of which cyclophosphamide is the first listed.

NCT00002547 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00002547 about?

NCT00002547 is a clinical study titled "Chemotherapy and Bone Marrow Transplantation in Treating Patients Acute Myeloid With Leukemia or Myelodysplastic Syndrome". RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with bone marrow transplantation may allow the doctor to give higher doses of chemotherapy and kill more cancer cells. PURPOSE: Phase II trial to study the...

What is the current status of trial NCT00002547?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 280 participants. The study started on 1987-08. Estimated completion is 2003-10.

What interventions are being tested in trial NCT00002547?

The interventions under investigation include: cyclophosphamide (DRUG), methotrexate (DRUG), cytarabine (DRUG), busulfan (DRUG), cyclosporine (DRUG).

Who is sponsoring clinical trial NCT00002547?

This trial is sponsored by Barbara Ann Karmanos Cancer Institute, which has 139 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00002547's enrollment target sits among peer trials

280 196th of 2000 higher than 1,800 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00002547, the US trial registry maintained by the National Library of Medicine. NCT00002547 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.