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NCT00248482 · ClinicalTrials.gov registry record · Phase 2

Imatinib Mesylate After Irinotecan and Cisplatin in Treating Patients With Extensive-Stage Small Cell Lung Cancer

A Phase 2 study of Lung Cancer, sponsored by Barbara Ann Karmanos Cancer Institute.

Completed
Registry status
Phase 2
Development phase
6
Enrollment target
2
Study locations

NCT00248482 is a Phase 2 study of Lung Cancer that has completed, run by Barbara Ann Karmanos Cancer Institute. The registered enrollment target is 6 participants, below the 936-participant average among 409 other Lung Cancer trials with a reported enrollment target (99% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT00248482, a Phase 2 study of Lung Cancer, has completed, sponsored by Barbara Ann Karmanos Cancer Institute.

COMPLETED
Registry status
Phase 2
Development phase
6 participants
Enrollment target
2
Study locations

Study Summary

RATIONALE: Imatinib mesylate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as irinotecan and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. Giving imatinib mesylate after irinotecan and cisplatin may keep the tumor from coming back. PURPOSE: This phase II trial is studying how well giving imatinib mesylate after irinotecan and cisplatin works in treating patients with extensive-stage small cell lung cancer.

Conditions Studied

Interventions

  • DRUG Cisplatin
  • DRUG irinotecan
  • DRUG Gleevec™

Study Locations (2)

Michigan

  • University of Michigan Comprehensive Cancer Center - Ann Arbor
  • Barbara Ann Karmanos Cancer Institute - Detroit

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2002-02
Est. Completion 2008-01
Phase Phase 2

What the Registry Record Tells You About NCT00248482

The ClinicalTrials.gov registry entry for NCT00248482 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 6 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 936-participant average among 409 other Lung Cancer trials with a reported enrollment target (99% lower). The listed sponsor is Barbara Ann Karmanos Cancer Institute, which has 139 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Lung Cancer appearing as the primary indexed condition, and to 3 interventions - of which Cisplatin is the first listed.

NCT00248482 reports 2 study locations spanning 1 distinct geographic area - top geographies include Michigan.

Frequently Asked Questions

What is clinical trial NCT00248482 about?

NCT00248482 is a clinical study titled "Imatinib Mesylate After Irinotecan and Cisplatin in Treating Patients With Extensive-Stage Small Cell Lung Cancer". RATIONALE: Imatinib mesylate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as irinotecan and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividin...

What is the current status of trial NCT00248482?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 6 participants. The study started on 2002-02. Estimated completion is 2008-01.

What conditions does trial NCT00248482 study?

This clinical trial studies the following conditions: Lung Cancer.

What interventions are being tested in trial NCT00248482?

The interventions under investigation include: Cisplatin (DRUG), irinotecan (DRUG), Gleevec™ (DRUG).

Who is sponsoring clinical trial NCT00248482?

This trial is sponsored by Barbara Ann Karmanos Cancer Institute, which has 139 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00248482 being conducted?

This trial has 2 study locations across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.