4D Molecular Therapeutics
Trial Pipeline
Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration
NCT07064759
4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration
NCT06864988
4D-710 in Adult Patients With Cystic Fibrosis
NCT05248230
4D-150 in Patients With Neovascular (Wet) Age-Related Macular Degeneration
NCT05197270
4D-150 in Patients With Diabetic Macular Edema
NCT05930561
An Open-label, Phase 1/2 Trial of Gene Therapy 4D-310 in Adults With Fabry Disease
NCT04519749
4D-125 in Patients With X-Linked Retinitis Pigmentosa (XLRP)
NCT04517149
Dose Escalation Study of Intravitreal 4D-110 in Patients With Choroideremia
NCT04483440
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 32 |
| Phase 2 | 2 |
| Phase 3 | 2 |
Therapeutic Areas
What the Pipeline for 4D Molecular Therapeutics Shows
According to the ClinicalTrials.gov registry, 4D Molecular Therapeutics is linked to 36 US clinical trials across every stage of research activity. Of those, 32 studies are currently recruiting — about 89% of the sponsor's indexed portfolio — and 0 are already marked complete, representing roughly 0% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
The phase mix for 4D Molecular Therapeutics reports 2 late-stage studies (Phase 3 and Phase 4 combined) and 34 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
The top therapeutic focus area indexed for 4D Molecular Therapeutics is X-Linked Retinitis Pigmentosa with 1 linked trial, and 8 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology — how this data is sourced, computed, and verified.