Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03488524 · ClinicalTrials.gov registry record · Phase 2
Open Label Extension Study of AMX0035 in Patients With ALS
A Phase 2 study of Amyotrophic Lateral Sclerosis and ALS, sponsored by Amylyx Pharmaceuticals.
- Completed
- Registry status
- Phase 2
- Development phase
- 90
- Enrollment target
- 20
- Study locations
NCT03488524 is a Phase 2 study of Amyotrophic Lateral Sclerosis and ALS that has completed, run by Amylyx Pharmaceuticals. The registered enrollment target is 90 participants, below the 897-participant average among 102 other Amyotrophic Lateral Sclerosis trials with a reported enrollment target (90% lower). The trial reports 20 study locations across 17 states.
The verdict
NCT03488524, a Phase 2 study of Amyotrophic Lateral Sclerosis and ALS, has completed, sponsored by Amylyx Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 90 participants
- Enrollment target
- 20
- Study locations
Study Summary
This extension study, in which all participants received active treatment (AMX0035), was designed to assess the longer-term safety and therapeutic potential of AMX0035 for participants who have completed the Main Study (AMX3500, also known as CENTAUR).
Conditions Studied
Interventions
- DRUG AMX0035
Study Locations (20)
California
- University of California, Irvine - Orange
- California Pacific Medical Center - San Francisco
Florida
- University of Florida College of Medicine - Gainesville
- University of South Florida College of Medicine - Tampa
Massachusetts
- Massachusetts General Hospital - Boston
- University of Massachusetts Memorial Medical Center - Worcester
Arizona
- Barrow Neurological Institute-Dignity Health, St Joseph's Hospital and Medical Center - Phoenix
Georgia
- Emory University Hospital - Atlanta
Iowa
- University of Iowa, Carver College of Medicine - Iowa City
Kentucky
- University of Kentucky Medical Center - Lexington
Louisiana
- Ochsner Neuroscience Institute - New Orleans
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2018-03-29 |
| Est. Completion | 2021-03-01 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03488524
The ClinicalTrials.gov registry entry for NCT03488524 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 90 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 897-participant average among 102 other Amyotrophic Lateral Sclerosis trials with a reported enrollment target (90% lower). The listed sponsor is Amylyx Pharmaceuticals, which has 9 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Amyotrophic Lateral Sclerosis appearing as the primary indexed condition, and to 1 intervention - of which AMX0035 is the first listed.
NCT03488524 reports 20 study locations spanning 17 distinct geographic areas - top geographies include California, Florida, Massachusetts.
Frequently Asked Questions
What is clinical trial NCT03488524 about?
NCT03488524 is a clinical study titled "Open Label Extension Study of AMX0035 in Patients With ALS". This extension study, in which all participants received active treatment (AMX0035), was designed to assess the longer-term safety and therapeutic potential of AMX0035 for participants who have completed the Main Study (AMX3500, also known as CENTAUR).
What is the current status of trial NCT03488524?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 90 participants. The study started on 2018-03-29. Estimated completion is 2021-03-01.
What conditions does trial NCT03488524 study?
This clinical trial studies the following conditions: Amyotrophic Lateral Sclerosis, ALS.
What interventions are being tested in trial NCT03488524?
The interventions under investigation include: AMX0035 (DRUG).
Who is sponsoring clinical trial NCT03488524?
This trial is sponsored by Amylyx Pharmaceuticals, which has 9 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03488524 being conducted?
This trial has 20 study locations across Arizona, California, Florida, Georgia, Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Amyotrophic Lateral Sclerosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Dazucorilant in Patients With Amyotrophic Lateral Sclerosis
RECRUITING · Phase 2
-
HEALEY ALS Platform Trial - Master Protocol
RECRUITING · Phase 2
-
RAPA-501 Therapy for ALS
RECRUITING · Phase 2
-
A Study of Ranolazine in ALS
RECRUITING · Phase 2
-
Rho Kinase Inhibitor in Amyotrophic Lateral Sclerosis (REAL)
ACTIVE NOT RECRUITING · Phase 2
-
Evaluation of MN-166 (Ibudilast) for 12 Months Followed by an Open-label Extension for 6 Months in Patients With ALS
ACTIVE NOT RECRUITING · Phase 2
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.