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NCT04156100 · ClinicalTrials.gov registry record · Phase 1

A Study in Subjects With Advanced Solid Tumors

A Phase 1 study, sponsored by Agenus.

Terminated
Registry status
Phase 1
Development phase
19
Enrollment target

NCT04156100 is a Phase 1 study that was terminated before completion, run by Agenus. The registered enrollment target is 19 participants.

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The verdict

NCT04156100, a Phase 1 study, was terminated before completion, sponsored by Agenus.

TERMINATED
Registry status
Phase 1
Development phase
19 participants
Enrollment target

Study Summary

This study is an open-label, Phase 1 study to evaluate the safety, tolerability, PK, and pharmacodynamic profiles of AGEN1223 as a single-agent and in combination with balstilimab, as well as to assess the maximum tolerated dose and determine the RP2D of AGEN1223 as a single-agent and in combination with balstilimab in subjects with advanced solid tumors.

Interventions

  • DRUG AGEN1223
  • DRUG AGEN1223 and balstilimab

Trial Details

FieldValue
Enrollment Target 19 participants
Start Date 2019-12-10
Est. Completion 2021-09-29
Phase Phase 1

Sponsor

Agenus

24 total trials

What the Registry Record Tells You About NCT04156100

The ClinicalTrials.gov registry entry for NCT04156100 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 19 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Agenus, which has 24 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which AGEN1223 is the first listed.

NCT04156100 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04156100 about?

NCT04156100 is a clinical study titled "A Study in Subjects With Advanced Solid Tumors". This study is an open-label, Phase 1 study to evaluate the safety, tolerability, PK, and pharmacodynamic profiles of AGEN1223 as a single-agent and in combination with balstilimab, as well as to assess the maximum tolerated dose and determine the RP2D of AGEN1223 as a single-agent and in combination...

What is the current status of trial NCT04156100?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 19 participants. The study started on 2019-12-10. Estimated completion is 2021-09-29.

What interventions are being tested in trial NCT04156100?

The interventions under investigation include: AGEN1223 (DRUG), AGEN1223 and balstilimab (DRUG).

Who is sponsoring clinical trial NCT04156100?

This trial is sponsored by Agenus, which has 24 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.