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NCT03894215 · ClinicalTrials.gov registry record · Phase 2
RaPiDS- A Phase 2 Study of Anti-PD-1 Independently or in Combination With Anti-CTLA-4 in Second-Line Cervical Cancer
A Phase 2 study of Cervical Cancer, sponsored by Agenus.
- Active
- Registry status
- Phase 2
- Development phase
- 212
- Enrollment target
- 20
- Study locations
NCT03894215 is a Phase 2 study of Cervical Cancer that is active but no longer recruiting, run by Agenus. The registered enrollment target is 212 participants, below the 569-participant average among 144 other Cervical Cancer trials with a reported enrollment target (63% lower). The trial reports 20 study locations across 11 states.
The verdict
NCT03894215, a Phase 2 study of Cervical Cancer, is active but no longer recruiting, sponsored by Agenus.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 212 participants
- Enrollment target
- 20
- Study locations
Study Summary
This is a randomized, blinded, non-comparative, two-arm Phase 2 clinical trial to assess the efficacy and safety of AGEN2034 administered with placebo (Treatment Arm 1 - monotherapy) or with AGEN1884 (Treatment Arm 2- combination therapy) for treatment of patients with advanced cervical cancer who relapsed or progressed after receiving first-line platinum-based chemotherapy. The study is not intended to compare the efficacy of the 2 experimental arms. Rather, the efficacy of each arm will be evaluated against its relevant historical controls as appropriate.
Conditions Studied
Interventions
- DRUG AGEN2034
- DRUG AGEN1884
Study Locations (20)
California
- University of California, San Diego (UCSD) - Moores Cancer Center - La Jolla
- UCLA- Women's Health Clinical Research Unit (WHCRU) - Los Angeles
- Gynecologic Oncology Associates - Newport
- California Pacific Medical Center - San Francisco
- University of California, San Francisco Medical Center - San Francisco
Alabama
- University of Alabama at Birmingham School of Medicine - Birmingham
- University of South Alabama Mitchell Cancer Institute - Mobile
Arizona
- Arizona Oncology - Biltmore Cancer Center - Phoenix
- Arizona Oncology - Tucson - Wilmot Road Location - Tucson
Florida
- Baptist MD Anderson Cancer Center - Jacksonville
- Moffitt Cancer Center - Tampa
Georgia
- Northside Hospital - Atlanta
- St Joseph's Hospital - Savannah
New York
- Northwell Health Monter Cancer Center - Lake Success
- Laura and Isaac Perlmutter Cancer Center at NYU Langone - New York
Indiana
- Community Health Network - North Cancer Center - Indianapolis
Kentucky
- University of Kentucky Albert B. Chandler Hospital - Lexington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 212 participants |
| Start Date | 2019-06-01 |
| Est. Completion | 2026-09 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03894215
The ClinicalTrials.gov registry entry for NCT03894215 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 212 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 569-participant average among 144 other Cervical Cancer trials with a reported enrollment target (63% lower). The listed sponsor is Agenus, which has 24 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Cervical Cancer appearing as the primary indexed condition, and to 2 interventions - of which AGEN2034 is the first listed.
NCT03894215 reports 20 study locations spanning 11 distinct geographic areas - top geographies include California, Alabama, Arizona.
Frequently Asked Questions
What is clinical trial NCT03894215 about?
NCT03894215 is a clinical study titled "RaPiDS- A Phase 2 Study of Anti-PD-1 Independently or in Combination With Anti-CTLA-4 in Second-Line Cervical Cancer". This is a randomized, blinded, non-comparative, two-arm Phase 2 clinical trial to assess the efficacy and safety of AGEN2034 administered with placebo (Treatment Arm 1 - monotherapy) or with AGEN1884 (Treatment Arm 2- combination therapy) for treatment of patients with advanced cervical cancer who r...
What is the current status of trial NCT03894215?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 212 participants. The study started on 2019-06-01. Estimated completion is 2026-09.
What conditions does trial NCT03894215 study?
This clinical trial studies the following conditions: Cervical Cancer.
What interventions are being tested in trial NCT03894215?
The interventions under investigation include: AGEN2034 (DRUG), AGEN1884 (DRUG).
Who is sponsoring clinical trial NCT03894215?
This trial is sponsored by Agenus, which has 24 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03894215 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.