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Tuberous Sclerosis Complex: full-pipeline trial registry
2 of 9 indexed Tuberous Sclerosis Complex trials are currently recruiting.
Corpus placement: #1,916 of 28,707 conditions by registered trial count.
9 US clinical trials · 2 currently recruiting · #1,916 of 28,707 conditions by registered trial count
Tuberous Sclerosis Complex: 9 US clinical trials tracked, 2 recruiting.
Tuberous Sclerosis Complex is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is David M. Ritter, running 1 of these trials.
Enrollment posture brief
Registry condition tuberous-sclerosis-complex
OPEN 2 | RECR 22% | LATE 2 | EARLY 3 | RANK #1916 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Acne (22% recruiting · 27 trials)
Tuberous Sclerosis Complex lists 2 open slots (22% of 9 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Tuberous Sclerosis Complex on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Tuberous Sclerosis Complex is recruiting below its size-band peers.
2 of 9 indexed trials (22.2%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Tuberous Sclerosis Complex trials is spread across many organizations.
David M. Ritter accounts for 1 of 9 trials (11.1%). 9 distinct sponsors appear on at least one study for this condition label.
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Typical Tuberous Sclerosis Complex enrolment sits around 64 participants.
Median target enrolment is 64 among the 9 trials that report a genuine target (sentinel values excluded). 5 of those (55.6%) plan for fewer than 100 participants.
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Tuberous Sclerosis Complex splits between interventional and observational designs.
6 interventional and 3 observational studies make up this index (66.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
9 total, page 1 of 1
Tuberous Sclerosis Complex and Lymphangioleiomyomatosis Pregnancy Registry (TSC-LAM Registry)
David M. Ritter
NCT06160310
Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study
Darcy Krueger
NCT05104983
Roll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXIST-3 Study [CRAD001M2304] and Who Are Benefitting From Continued Treatment
Novartis Pharmaceuticals
NCT02962414
Assessment of Potential for Chronic Liver Injury in Participants Treated With Epidiolex (Cannabidiol) Oral Solution
Jazz Pharmaceuticals
NCT05044819
Feasibility of [11C]Acetate-PET in LAM and TSC
Brigham and Women's Hospital
NCT05467397
Tuberous Sclerosis Complex Natural History Study: Renal Manifestations
Children's Hospital Medical Center, Cincinnati
NCT00598455
Potential EEG Biomarkers and Antiepileptogenic Strategies for Epilepsy in TSC
University of Alabama at Birmingham
NCT01767779
Everolimus for Cancer With TSC1 or TSC2 Mutation
Dana-Farber Cancer Institute
NCT02201212
Early Behavioral Intervention to Improve Social Communication Function in Infants With Tuberous Sclerosis Complex
University of California, Los Angeles
NCT02687633
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 2 |
| Phase 3 | 1 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Tuberous Sclerosis Complex records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Tuberous Sclerosis Complex trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Tuberous Sclerosis Complex page
9 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 2 Tuberous Sclerosis Complex trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- David M. Ritter sponsors the most Tuberous Sclerosis Complex trials on record, review their full trial history before evaluating a specific study. See David M. Ritter's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Tuberous Sclerosis Complex condition card totals 9 registered trials; most-linked intervention [11C]acetate; top US site state Ohio. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.