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ClinicalTrials.gov 15 recruiting now full pipeline

Tobacco Smoking: full-pipeline trial registry

15 of 39 indexed Tobacco Smoking trials are currently recruiting.

Corpus placement: #382 of 28,707 conditions by registered trial count.

39 US clinical trials · 15 currently recruiting · #382 of 28,707 conditions by registered trial count

Tobacco Smoking: 39 US clinical trials tracked, 15 recruiting.

Tobacco Smoking is the subject of 39 registered US clinical trials on ClinicalTrials.gov, 15 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Johns Hopkins University, running 5 of these trials.

Enrollment posture brief

Registry condition tobacco-smoking

OPEN 15 | RECR 38% | LATE 4 | EARLY 5 | RANK #382 | SPON 5

Nearest open-share peer: Anaplastic Oligodendroglioma (38% recruiting · 13 trials)

B-cell Lymphoma46.2%Binge-Eating Disorder43.6%Kidney Diseases38.5%Tobacco Smoking (this)38%Acute Myelogenous Leukemia17.9%
Open-enrollment share among volume-matched conditions near Tobacco Smoking

Tobacco Smoking lists 15 open slots (38% of 39 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Tobacco Smoking on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Tobacco Smoking recruits in line with its size-band peers.

    15 of 39 indexed trials (38.5%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Tobacco Smoking trials is spread across many organizations.

    Johns Hopkins University accounts for 5 of 39 trials (12.8%). 25 distinct sponsors appear on at least one study for this condition label.

  3. Typical Tobacco Smoking enrolment sits around 91 participants.

    Median target enrolment is 91 among the 39 trials that report a genuine target (sentinel values excluded). 21 of those (53.8%) plan for fewer than 100 participants.

  4. Tobacco Smoking research is mostly interventional.

    37 interventional and 2 observational studies make up this index (94.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 22Phase 31Phase 43

Open and recent trials

39 total, page 1 of 1

RECRUITING 5,122 participants

The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Malignant Disorders and Oral Cancer Amongst the Rural Population of Varanasi: A Prospective and Blinded Study

Memorial Sloan Kettering Cancer Center

NCT06535867

RECRUITING NA 5,000 participants

CONNECT Cancer Survivors With Tobacco Treatment

Washington University School of Medicine

NCT07020273

RECRUITING NA 1,560 participants

Reach Through Equitable Implementation in Utah

University of Utah

NCT06881069

RECRUITING Phase 4 608 participants

Smoking Cessation Program in the Construction Sector

University of Miami

NCT06098144

RECRUITING NA 544 participants

Smoke-free Home Study in Subsidized Housing

University of California, San Francisco

NCT06170437

RECRUITING Phase 3 270 participants

Intervention to Increase Intention to Change Alcohol/Tobacco Use in Veterans With Chronic Disease

VA Office of Research and Development

NCT07039175

RECRUITING Phase 2 120 participants

Cannabidiol for Reducing Cigarette Use

University of California, Los Angeles

NCT06218056

RECRUITING NA 120 participants

Development of a Smoking Cessation Video Series

Wayne State University

NCT06443294

RECRUITING NA 120 participants

Using Novel Behavioral Economic Measures to Characterize Dual Marijuana and Tobacco Use in Young Adults

Brown University

NCT07398443

RECRUITING Phase 1 90 participants

Effects of Cannabidiol on Stress and Nicotine Withdrawal

Johns Hopkins University

NCT07001930

RECRUITING Phase 1 50 participants

Oral Cannabidiol for Tobacco Cessation

Johns Hopkins University

NCT05445804

RECRUITING NA 40 participants

Abuse Liability for Five Modern Oral Nicotine Products

RAI Services Company

NCT07132814

RECRUITING NA 20 participants

Trauma-Informed Care for Smoking Cessation for Pregnancy

University of California, San Francisco

NCT07129590

RECRUITING Phase 4 10 participants

Smoking Cessation With Varenicline in Schizophrenia: Antipsychotic-Induced Neurological Symptoms as Correlates

Corporal Michael J. Crescenz VA Medical Center

NCT03495024

RECRUITING NA 10 participants

A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free Home

Memorial Sloan Kettering Cancer Center

NCT06693700

ACTIVE NOT RECRUITING NA 150 participants

Potential Impact of Menthol Ban in Cigarettes and E-cigarettes

Yale University

NCT05259566

ACTIVE NOT RECRUITING 60 participants

The Effect of Tobacco Products on Wound Healing

University of Minnesota

NCT04870970

ACTIVE NOT RECRUITING Phase 2 19 participants

Nivolumab for the Reversal of Squamous Dysplasia in High Risk Current and Former Smokers

University of Colorado, Denver

NCT03347838

COMPLETED NA 1,944 participants

Helping Poor Smokers Quit

Washington University School of Medicine

NCT03194958

COMPLETED NA 679 participants

Evaluation of the Media Detective Program for Elementary School-Aged Children to Prevention Substance Use

Innovation Research & Training

NCT01060852

COMPLETED NA 264 participants

Methods Project 4: Clinical Trial - Amended

University of Minnesota

NCT03111537

COMPLETED NA 194 participants

CSD210903: A Study to Determine Subject Puffing Patterns of a Heated Tobacco Product With Four Non-Combusted Cigarette Variants in an Ambulatory Setting

RAI Services Company

NCT05307822

COMPLETED NA 165 participants

A Facebook Intervention for Young Sexual and Gender Minority Smokers

University of California, San Francisco

NCT03259360

COMPLETED NA 158 participants

Innovative Digital Therapeutic for Smoking Cessation

My Digital Study

NCT03694327

COMPLETED NA 121 participants

A Guided Imagery Tobacco Cessation Intervention Delivered by a Quit Line and Website

University of Arizona

NCT02968381

COMPLETED NA 103 participants

Developing Genetic Education for Smoking Cessation

University of Nebraska

NCT01186016

COMPLETED NA 99 participants

Recruitment Messages for Current Smokers Recently Diagnosed With Cancer

University of Oklahoma

NCT05471284

COMPLETED NA 91 participants

Promoting Evidenced-Based Tobacco Smoking Cessation Treatment in Community Mental Health Clinics

Johns Hopkins University

NCT04796961

COMPLETED NA 75 participants

CSD200907: A Study to Assess Elements of Abuse Liability for a Heated Tobacco Product With Four Non-Combusted Cigarette Variants

RAI Services Company

NCT05114863

COMPLETED NA 61 participants

Connecting Alaska Native People to Quit Smoking

Mayo Clinic

NCT03645941

COMPLETED Phase 4 58 participants

Tobacco and Socioeconomic Disadvantage

Rutgers, The State University of New Jersey

NCT03620708

COMPLETED NA 42 participants

CSD201301: Study to Assess Elements of Abuse Liability for Four P13 Nicotine Pouches

RAI Services Company

NCT05294497

COMPLETED NA 42 participants

Effects of Nature Exposure on Smoking Behavior

University of Montana

NCT03716440

COMPLETED NA 37 participants

Acute Effects of TCIG vs ECIG in PLWH

University of California, Los Angeles

NCT04568395

COMPLETED NA 36 participants

A Study to Assess the Pharmacokinetics of Oral Nicotine Pouches and Lozenges in Healthy Adults

British American Tobacco (Investments) Limited

NCT04755348

COMPLETED NA 18 participants

Pilot Testing a Computer Delivered Tobacco Cessation Intervention in Outpatient Clinical Settings: A Feasibility Study

Johns Hopkins University

NCT05145738

COMPLETED NA 17 participants

Evaluating the Comparative Pharmacokinetics of Nicotine After Administration Via JUUL or Tobacco Cigarettes

University of California, San Francisco

NCT04053868

COMPLETED Phase 1 15 participants

Brain Imaging in Tobacco Smokers During a Quit Attempt

Johns Hopkins University

NCT04055467

COMPLETED NA 7 participants

E-cigarettes to Promote Smoking Reduction Among Individuals With Schizophrenia

The University of Texas Health Science Center, Houston

NCT02918630

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 2
Phase 3 1
Phase 4 3

Named interventions

Most-linked intervention names on Tobacco Smoking records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Product D Other
4 trials
Product C Other
4 trials
Product B Other
4 trials
Product A Other
3 trials
Product E Other
2 trials
Placebo Drug
2 trials
Media Detective Behavioral
1 trials
Tobacco Other
1 trials

US sites by state

Facility locations filed on Tobacco Smoking trials. A trial with sites in several states counts in each.

California 6 trials
New York 5 trials
Maryland 5 trials
Minnesota 3 trials
Texas 2 trials
Tennessee 2 trials
New Jersey 2 trials
North Carolina 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Tobacco Smoking page

39 registered trials, 15 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Tobacco Smoking condition card totals 39 registered trials; most-linked intervention Product D; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.