Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03111537 · ClinicalTrials.gov registry record · NA

Methods Project 4: Clinical Trial - Amended

A NA study of Tobacco Smoking, sponsored by University of Minnesota.

Completed
Registry status
NA
Development phase
264
Enrollment target
3
Study locations

NCT03111537: Completed NA study of Tobacco Smoking, sponsored by University of Minnesota.

NCT03111537 is a NA study of Tobacco Smoking that has completed, run by University of Minnesota. The registered enrollment target is 264 participants, below the 470-participant average among 38 other Tobacco Smoking trials with a reported enrollment target (44% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03111537, a NA study of Tobacco Smoking, has completed, sponsored by University of Minnesota.

COMPLETED
Registry status
NA
Development phase
264 participants
Enrollment target
3
Study locations

Study Summary

Cigarette smokers will be randomized to E-cigarette, Nicotine Gum or Lozenge, or Control Group. Participants will enter a 1 week sampling phase. Smokers interested in continuing with the study after the sampling phase will undergo a 2 week baseline assessment phase and will then enter an 8 week intervention. Tobacco use patterns, subjective responses to product, and nicotine and toxicant exposure will be assessed.

Primary Outcome

Compare the exposure to nicotine in the two instructions for use arms (complete substitution vs. partial substitution) across study products and compared to medicinal nicotine products and usual brand cigarettes.

Conditions Studied

Interventions

  • OTHER Cigarettes
  • OTHER E-Cigarette
  • OTHER Nicotine Gum or Lozenge

Study Locations (3)

Minnesota

  • Masonic Cancer Center, University of Minnesota - Minneapolis

New York

  • Roswell Park Cancer Center - Buffalo

Ohio

  • Ohio State University Comprehensive Cancer Center - Columbus

Trial Details

FieldValue
Enrollment Target 264 participants
Start Date 2015-05
Est. Completion 2018-02
Phase NA
University of Minnesota

966 total trials

What the finished NCT03111537 record still lists

NCT03111537 is an interventional study that assigns participants to a tested intervention. The registered 264 participants enrollment target is mid-sized for trials with a published cap, below the 470-participant average among 38 other Tobacco Smoking trials with a reported enrollment target (44% lower).

The record links to 1 condition, with Tobacco Smoking appearing as the primary indexed condition, and to 3 interventions - of which Cigarettes is the first listed.

NCT03111537 reports a single indexed study location in Minnesota, New York, Ohio.

Frequently Asked Questions

What is clinical trial NCT03111537 about?

NCT03111537 is a clinical study titled "Methods Project 4: Clinical Trial - Amended". Cigarette smokers will be randomized to E-cigarette, Nicotine Gum or Lozenge, or Control Group. Participants will enter a 1 week sampling phase. Smokers interested in continuing with the study after the sampling phase will undergo a 2 week baseline assessment phase and will then enter an 8 week inte...

What is the current status of trial NCT03111537?

This trial is currently completed. It is a NA study. The enrollment target is 264 participants. The study started on 2015-05. Estimated completion is 2018-02.

What conditions does trial NCT03111537 study?

This clinical trial studies the following conditions: Tobacco Smoking.

What interventions are being tested in trial NCT03111537?

The interventions under investigation include: Cigarettes (OTHER), E-Cigarette (OTHER), Nicotine Gum or Lozenge (OTHER).

Who is sponsoring clinical trial NCT03111537?

This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03111537 being conducted?

This trial has 3 study locations across Minnesota, New York, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Tobacco Smoking

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03111537's enrollment target sits among peer trials

264 9th of 38 higher than 30 of 38 other Tobacco Smoking trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Tobacco Smoking trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT04101669 · 264 participants · NA

    RESET System Pivotal Trial (Rev F)

  • NCT04295863 · 264 participants · Phase 1

    Comparing Dosing Intervals of Nivolumab or Pembrolizumab in Locally Advanced or Metastatic Cancers

  • NCT05220202 · 264 participants · NA

    MOTIVATE to Improve Outcomes for Older Veterans With Musculoskeletal Pain and Depression

  • NCT05473013 · 264 participants · NA

    Optimizing Digital Health Technology Interventions to Increase Skill Acquisition and Utilization

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT03111537, the US trial registry maintained by the National Library of Medicine. NCT03111537 (mid enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.