Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
TBI (Traumatic Brain Injury): early-phase trial registry
16 of 21 indexed TBI (Traumatic Brain Injury) trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #797 of 28,707 conditions by registered trial count.
21 US clinical trials · 16 currently recruiting · #797 of 28,707 conditions by registered trial count
TBI (Traumatic Brain Injury): 21 US clinical trials tracked, 16 recruiting.
TBI (Traumatic Brain Injury) is the subject of 21 registered US clinical trials on ClinicalTrials.gov, 16 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is University of Minnesota, running 3 of these trials.
Enrollment posture brief
Registry condition tbi-traumatic-brain-injury
OPEN 16 | RECR 76% | LATE 0 | EARLY 4 | RANK #797 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Hematopoietic and Lymphatic System Neoplasm (76% recruiting · 63 trials)
TBI (Traumatic Brain Injury) lists 16 open slots (76% of 21 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for TBI (Traumatic Brain Injury) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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TBI (Traumatic Brain Injury) is recruiting above its size-band peers.
16 of 21 indexed trials (76.2%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of TBI (Traumatic Brain Injury) trials is spread across many organizations.
University of Minnesota accounts for 3 of 21 trials (14.3%). 18 distinct sponsors appear on at least one study for this condition label.
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Typical TBI (Traumatic Brain Injury) enrolment sits around 89 participants.
Median target enrolment is 89 among the 21 trials that report a genuine target (sentinel values excluded). 12 of those (57.1%) plan for fewer than 100 participants.
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TBI (Traumatic Brain Injury) research is mostly interventional.
16 interventional and 5 observational studies make up this index (76.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
21 total, page 1 of 1
Augmented Renal Clearance in Neurocritical Care
University of Alberta
NCT07410624
Emergency Department Implementation of the i-STAT Alinity Traumatic Brain Injury Whole Blood Test
Shawn Eagle
NCT07373509
Biomarkers in the Brain Oxygen Optimization in Severe Traumatic Brain Injury Trial
University of Pennsylvania
NCT04565119
Combined Transcranial Magnetic Stimulation and Therapy for MTBI Related Headaches
Veterans Medical Research Foundation
NCT05176392
Behavioral Treatment of Insomnia in Active-Duty Service Members With Traumatic Brain Injury
Noctem
NCT06867666
Cerebral Autoregulation, Brain Perfusion, and Neurocognitive Outcomes After Traumatic Brain Injury
University of Texas Southwestern Medical Center
NCT06480838
Mindfulness for Cognition in Early-stage Alzheimer's Disease
VA Boston Healthcare System
NCT06792877
Evaluation of Well-being Interventions in Adults With TBI
Kessler Foundation
NCT05943756
InMotion - Telehealth Delivered Exercise Promotion to Treat Major Depression After TBI
University of Washington
NCT06005194
Veterans' Cognitive Function, Mental Health, and Quality of Life After Hyperbaric Oxygen Therapy
Summit Hyperbarics and Wellness
NCT07214415
Cognitive Rehabilitation for Refugees With Traumatic Brain Injury and Cognitive Impairment
Massachusetts General Hospital
NCT06839079
Transcutaneous Auricular Neurostimulation for ICU Patients With Traumatic Brain Injury
University of Texas Southwestern Medical Center
NCT06467708
Growth Hormone Replacement Therapy for Retried Professional Football Players
Center for Neurological Studies
NCT04121780
Evaluation of Decision-Making Fatigue After Traumatic Brain Injury
University of Minnesota
NCT07103200
Stimulating After Recovery From Traumatic Brain Injury
University of Minnesota
NCT05327829
Depth Electrode Detection of Cortical Spreading Depolarization After Traumatic Brain Injury
University of Minnesota
NCT05205174
Follow-up of MTBI Patients Discharged from the ED Using Standard Clinical Triage Including BrainScope One
BrainScope Company
NCT04279431
Autologous Stem Cell Study for Adult TBI (Phase 2b)
The University of Texas Health Science Center, Houston
NCT02525432
A Multi-Center Study of Near-Infrared Spectroscopy (NIRS) for Hematoma Detection
InfraScan
NCT00576147
Brain Aging in Veterans (BRAVE) Training: A Cognitive Training Pilot Trial in Older Veterans With Traumatic Brain Injury
San Francisco Veterans Affairs Medical Center
NCT02561403
VR Cognitive Rehabiliation for Pediatric TBI
University of Massachusetts, Lowell
NCT04526639
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on TBI (Traumatic Brain Injury) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on TBI (Traumatic Brain Injury) trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this TBI (Traumatic Brain Injury) page
21 registered trials, 16 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 16 TBI (Traumatic Brain Injury) trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Minnesota sponsors the most TBI (Traumatic Brain Injury) trials on record, review their full trial history before evaluating a specific study. See University of Minnesota's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This TBI (Traumatic Brain Injury) condition card totals 21 registered trials; most-linked intervention COGED; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.