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NCT06480838 · ClinicalTrials.gov registry record
Cerebral Autoregulation, Brain Perfusion, and Neurocognitive Outcomes After Traumatic Brain Injury
A clinical trial of TBI (Traumatic Brain Injury) and TBI, sponsored by University of Texas Southwestern Medical Center.
- Recruiting
- Registry status
- 130
- Enrollment target
- 3
- Study locations
NCT06480838 is a study of TBI (Traumatic Brain Injury) and TBI that is actively recruiting participants, run by University of Texas Southwestern Medical Center. The registered enrollment target is 130 participants, below the 167-participant average among 20 other TBI (Traumatic Brain Injury) trials with a reported enrollment target (22% lower). The trial reports 3 study locations across 1 state.
The verdict
NCT06480838, a study of TBI (Traumatic Brain Injury) and TBI, is actively recruiting participants, sponsored by University of Texas Southwestern Medical Center.
- RECRUITING
- Registry status
- 130 participants
- Enrollment target
- 3
- Study locations
Study Summary
Cognitive impairment after moderate to severe traumatic brain injury (msTBI) not only significantly affects the quality of life in individuals with msTBI, but also increases the possibility of late-life dementia. The goal of this study is to determine whether acute (\< 1 week) cerebrovascular injury and its recovery within the first year postinjury measured by cerebral autoregulation and brain perfusion are associated with cognitive outcome at 12 months after msTBI. The results from this study will improve our understanding of cerebrovascular contributions to cognitive decline related to TBI and provide critical data to inform the development of strategies based on vascular mechanisms to improve cognition and prevent neurodegeneration after msTBI.
Conditions Studied
Study Locations (3)
Texas
- Texas Health Presbyterian Hospital - Dallas
- Parkland Health and Hospital System - Dallas
- UT Southwestern Medical Center - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 130 participants |
| Start Date | 2023-09-01 |
| Est. Completion | 2028-05-31 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06480838
The ClinicalTrials.gov registry entry for NCT06480838 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 130 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 167-participant average among 20 other TBI (Traumatic Brain Injury) trials with a reported enrollment target (22% lower). The listed sponsor is University of Texas Southwestern Medical Center, which has 837 total studies on file at ClinicalTrials.gov.
The record links to 5 conditions, with TBI (Traumatic Brain Injury) appearing as the primary indexed condition, and to 0 interventions.
NCT06480838 reports 3 study locations spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT06480838 about?
NCT06480838 is a clinical study titled "Cerebral Autoregulation, Brain Perfusion, and Neurocognitive Outcomes After Traumatic Brain Injury". Cognitive impairment after moderate to severe traumatic brain injury (msTBI) not only significantly affects the quality of life in individuals with msTBI, but also increases the possibility of late-life dementia. The goal of this study is to determine whether acute (\< 1 week) cerebrovascular injury...
What is the current status of trial NCT06480838?
This trial is currently recruiting. The enrollment target is 130 participants. The study started on 2023-09-01. Estimated completion is 2028-05-31.
What conditions does trial NCT06480838 study?
This clinical trial studies the following conditions: TBI (Traumatic Brain Injury), TBI, Traumatic Brain Injury With Loss of Consciousness, Brain Injury Traumatic Severe, Brain Injury Traumatic Moderate.
Who is sponsoring clinical trial NCT06480838?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06480838 being conducted?
This trial has 3 study locations across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.