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ClinicalTrials.gov 1 recruiting now official registry

Stage IV Pancreatic Cancer clinical trials

1 of 16 indexed Stage IV Pancreatic Cancer trials are currently recruiting.

16 US clinical trials · 1 currently recruiting

Stage IV Pancreatic Cancer is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 7 of these trials.

The research picture

Stage IV Pancreatic Cancer has 16 registered US clinical trials, 1 of them open to new participants right now, about 6% of the total.

1
recruiting participants now
6%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
7
top sponsor: National Cancer Institute (NCI)
Phase 18Phase 27Phase 31

Active & Recent Trials

16 total, page 1 of 1

RECRUITING Phase 2 89 participants

Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors

Rahul Aggarwal

NCT03682289

ACTIVE NOT RECRUITING Phase 1 64 participants

TAS102 in Combination With NAL-IRI in Advanced GI Cancers

Emory University

NCT03368963

ACTIVE NOT RECRUITING Phase 1 25 participants

Trametinib and Hydroxychloroquine in Treating Patients With Pancreatic Cancer

University of Utah

NCT03825289

COMPLETED Phase 3 590 participants

Gemcitabine With or Without Bevacizumab in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer

National Cancer Institute (NCI)

NCT00088894

COMPLETED Phase 2 116 participants

Triapine as First-Line or Second-Line Therapy in Treating Patients With Locally Advanced or Metastatic Cancer of the Pancreas

National Cancer Institute (NCI)

NCT00085371

COMPLETED Phase 1 60 participants

Gemcitabine+Nab-paclitaxel and FOLFIRINOX and Molecular Profiling for Patients With Advanced Pancreatic Cancer

Pancreatic Cancer Research Team

NCT01488552

COMPLETED Phase 2 52 participants

Sorafenib With or Without Gemcitabine in Treating Patients With Metastatic Pancreatic Cancer

National Cancer Institute (NCI)

NCT00114244

COMPLETED Phase 2 40 participants

CCI-779 in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer

National Cancer Institute (NCI)

NCT00075647

COMPLETED Phase 1 28 participants

Study of Gemcitabine + PEGPH20 vs Gemcitabine Alone in Stage IV Previously Untreated Pancreatic Cancer

Halozyme Therapeutics

NCT01453153

COMPLETED Phase 1 26 participants

Alisertib and Gemcitabine Hydrochloride in Treating Patients With Solid Tumors or Pancreatic Cancer

Edward Kim

NCT01924260

COMPLETED Phase 1 26 participants

Dovitinib Lactate, Gemcitabine Hydrochloride, and Capecitabine in Treating Patients With Advanced or Metastatic Solid Tumors, Pancreatic Cancer and Biliary Cancers

Roswell Park Cancer Institute

NCT01497392

COMPLETED Phase 1 25 participants

Nab-Pac+Cis+Gem in Pts w Previously Untreated Metastatic PDA

Pancreatic Cancer Research Team

NCT01893801

COMPLETED Phase 2 19 participants

Paclitaxel and Bryostatin 1 in Treating Patients With Advanced Pancreatic Cancer

National Cancer Institute (NCI)

NCT00031694

COMPLETED Phase 2 18 participants

Gamma Secretase Inhibitor RO4929097 in Previously Treated Metastatic Pancreas Cancer

National Cancer Institute (NCI)

NCT01232829

COMPLETED Phase 2 10 participants

Docetaxel and Flavopiridol in Treating Patients With Refractory Metastatic Pancreatic Cancer

National Cancer Institute (NCI)

NCT00331682

COMPLETED Phase 1 2 participants

BATS With in Combination With Low Dose IL-1 and GM-CSF for Advanced Pancreatic Cancer

Barbara Ann Karmanos Cancer Institute

NCT02620865

Phase Distribution

PhaseTrial count
Phase 1 8
Phase 2 7
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Stage IV Pancreatic Cancer Trial Landscape

16 indexed Stage IV Pancreatic Cancer studies · 1 recruiting (6%).

Phase mix: 1 late (III/IV) vs 15 early (I/II).

Top sponsor: National Cancer Institute (NCI) (7 trials), 8 others listed. 16 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Stage IV Pancreatic Cancer?

PlainTrial tracks 16 US clinical trials for Stage IV Pancreatic Cancer, of which 1 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Stage IV Pancreatic Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.