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ClinicalTrials.gov 1 recruiting now early-phase tilt small index

Stage IV Pancreatic Cancer: early-phase trial registry

1 of 16 indexed Stage IV Pancreatic Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,060 of 28,707 conditions by registered trial count.

16 US clinical trials · 1 currently recruiting · #1,060 of 28,707 conditions by registered trial count

Stage IV Pancreatic Cancer: 16 US clinical trials tracked, 1 recruiting.

Stage IV Pancreatic Cancer is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 7 of these trials.

Enrollment posture brief

Registry condition stage-iv-pancreatic-cancer

OPEN 1 | RECR 6% | LATE 1 | EARLY 15 | RANK #1060 | SPON 7

Nearest open-share peer: Recurrent Non-small Cell Lung Cancer (6% recruiting · 16 trials)

Adolescent62.5%Alcohol Intoxication56.3%AL Amyloidosis43.8%Allergy18.8%Stage IV Pancreatic Canc (th…6%
Open-enrollment share among volume-matched conditions near Stage IV Pancreatic Cancer

Stage IV Pancreatic Cancer lists 1 open slots (6% of 16 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Stage IV Pancreatic Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Stage IV Pancreatic Cancer is recruiting below its size-band peers.

    1 of 16 indexed trials (6.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Stage IV Pancreatic Cancer research.

    National Cancer Institute (NCI) accounts for 7 of 16 trials (43.8%). 9 distinct sponsors appear on at least one study for this condition label.

  3. Most Stage IV Pancreatic Cancer trials plan to enrol fewer than 100 people.

    Median target enrolment is 28 among the 16 trials that report a genuine target (sentinel values excluded). 14 of those (87.5%) plan for fewer than 100 participants.

  4. Stage IV Pancreatic Cancer research is mostly interventional.

    16 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 18Phase 27Phase 31

Open and recent trials

16 total, page 1 of 1

RECRUITING Phase 2 89 participants

Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors

Rahul Aggarwal

NCT03682289

ACTIVE NOT RECRUITING Phase 1 64 participants

TAS102 in Combination With NAL-IRI in Advanced GI Cancers

Emory University

NCT03368963

ACTIVE NOT RECRUITING Phase 1 25 participants

Trametinib and Hydroxychloroquine in Treating Patients With Pancreatic Cancer

University of Utah

NCT03825289

COMPLETED Phase 3 590 participants

Gemcitabine With or Without Bevacizumab in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer

National Cancer Institute (NCI)

NCT00088894

COMPLETED Phase 2 116 participants

Triapine as First-Line or Second-Line Therapy in Treating Patients With Locally Advanced or Metastatic Cancer of the Pancreas

National Cancer Institute (NCI)

NCT00085371

COMPLETED Phase 1 60 participants

Gemcitabine+Nab-paclitaxel and FOLFIRINOX and Molecular Profiling for Patients With Advanced Pancreatic Cancer

Pancreatic Cancer Research Team

NCT01488552

COMPLETED Phase 2 52 participants

Sorafenib With or Without Gemcitabine in Treating Patients With Metastatic Pancreatic Cancer

National Cancer Institute (NCI)

NCT00114244

COMPLETED Phase 2 40 participants

CCI-779 in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer

National Cancer Institute (NCI)

NCT00075647

COMPLETED Phase 1 28 participants

Study of Gemcitabine + PEGPH20 vs Gemcitabine Alone in Stage IV Previously Untreated Pancreatic Cancer

Halozyme Therapeutics

NCT01453153

COMPLETED Phase 1 26 participants

Alisertib and Gemcitabine Hydrochloride in Treating Patients With Solid Tumors or Pancreatic Cancer

Edward Kim

NCT01924260

COMPLETED Phase 1 26 participants

Dovitinib Lactate, Gemcitabine Hydrochloride, and Capecitabine in Treating Patients With Advanced or Metastatic Solid Tumors, Pancreatic Cancer and Biliary Cancers

Roswell Park Cancer Institute

NCT01497392

COMPLETED Phase 1 25 participants

Nab-Pac+Cis+Gem in Pts w Previously Untreated Metastatic PDA

Pancreatic Cancer Research Team

NCT01893801

COMPLETED Phase 2 19 participants

Paclitaxel and Bryostatin 1 in Treating Patients With Advanced Pancreatic Cancer

National Cancer Institute (NCI)

NCT00031694

COMPLETED Phase 2 18 participants

Gamma Secretase Inhibitor RO4929097 in Previously Treated Metastatic Pancreas Cancer

National Cancer Institute (NCI)

NCT01232829

COMPLETED Phase 2 10 participants

Docetaxel and Flavopiridol in Treating Patients With Refractory Metastatic Pancreatic Cancer

National Cancer Institute (NCI)

NCT00331682

COMPLETED Phase 1 2 participants

BATS With in Combination With Low Dose IL-1 and GM-CSF for Advanced Pancreatic Cancer

Barbara Ann Karmanos Cancer Institute

NCT02620865

Phase Distribution

PhaseTrial count
Phase 1 8
Phase 2 7
Phase 3 1

Named interventions

Most-linked intervention names on Stage IV Pancreatic Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

laboratory biomarker analysis Other
4 trials
gemcitabine hydrochloride Drug
3 trials
gemcitabine Drug
2 trials
nab-paclitaxel Drug
2 trials
Gemcitabine Drug
2 trials
dovitinib lactate Drug
1 trials
Immunohistochemistry (IHC) Analysis Genetic
1 trials
Antibody Therapy Biological
1 trials

US sites by state

Facility locations filed on Stage IV Pancreatic Cancer trials. A trial with sites in several states counts in each.

California 6 trials
New York 4 trials
Washington 2 trials
New Jersey 2 trials
Minnesota 2 trials
Illinois 2 trials
Arizona 2 trials
Utah 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Stage IV Pancreatic Cancer page

16 registered trials, 1 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stage IV Pancreatic Cancer condition card totals 16 registered trials; most-linked intervention laboratory biomarker analysis; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.