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NCT00085371 · ClinicalTrials.gov registry record · Phase 2

Triapine as First-Line or Second-Line Therapy in Treating Patients With Locally Advanced or Metastatic Cancer of the Pancreas

A Phase 2 study of Stage IV Pancreatic Cancer and Stage III Pancreatic Cancer, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 2
Development phase
116
Enrollment target
1
Study location

NCT00085371: Completed Phase 2 study of Stage IV Pancreatic Cancer and Stage III Pancreatic Cancer, sponsored by National Cancer Institute (NCI).

NCT00085371 is a Phase 2 study of Stage IV Pancreatic Cancer and Stage III Pancreatic Cancer that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 116 participants, above the 72-participant average among 15 other Stage IV Pancreatic Cancer trials with a reported enrollment target (61% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00085371, a Phase 2 study of Stage IV Pancreatic Cancer and Stage III Pancreatic Cancer, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 2
Development phase
116 participants
Enrollment target
1
Study location

Study Summary

This phase II trial is studying how well triapine works as first-line or second-line therapy in treating patients with locally advanced or metastatic adenocarcinoma (cancer) of the pancreas. Drugs used in chemotherapy, such as triapine, work in different ways to stop tumor cells from dividing so they stop growing or die.

Primary Outcome

The point estimate of the success rates will be calculated as the number of successes divided by the number of evaluable patients, with confidence intervals calculated by the method of Duffy and Santner.

Interventions

  • DRUG triapine

Study Locations (1)

Minnesota

  • Mayo Clinic - Rochester

Trial Details

FieldValue
Enrollment Target 116 participants
Start Date 2004-07
Phase Phase 2
National Cancer Institute (NCI)

3,257 total trials

What the finished NCT00085371 record still lists

NCT00085371 is an interventional study that assigns participants to a tested intervention. The registered 116 participants enrollment target is mid-sized for trials with a published cap, above the 72-participant average among 15 other Stage IV Pancreatic Cancer trials with a reported enrollment target (61% higher).

The record links to 5 conditions, with Stage IV Pancreatic Cancer appearing as the primary indexed condition, and to 1 intervention - of which triapine is the first listed.

NCT00085371 reports a single indexed study location in Minnesota.

Frequently Asked Questions

What is clinical trial NCT00085371 about?

NCT00085371 is a clinical study titled "Triapine as First-Line or Second-Line Therapy in Treating Patients With Locally Advanced or Metastatic Cancer of the Pancreas". This phase II trial is studying how well triapine works as first-line or second-line therapy in treating patients with locally advanced or metastatic adenocarcinoma (cancer) of the pancreas. Drugs used in chemotherapy, such as triapine, work in different ways to stop tumor cells from dividing so the...

What is the current status of trial NCT00085371?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 116 participants. The study started on 2004-07.

What conditions does trial NCT00085371 study?

This clinical trial studies the following conditions: Stage IV Pancreatic Cancer, Stage III Pancreatic Cancer, Recurrent Pancreatic Cancer, Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcinoma of the Pancreas.

What interventions are being tested in trial NCT00085371?

The interventions under investigation include: triapine (DRUG).

Who is sponsoring clinical trial NCT00085371?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00085371 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Stage IV Pancreatic Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00085371's enrollment target sits among peer trials

116 2nd of 15 the highest of 15 other Stage IV Pancreatic Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Stage IV Pancreatic Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00085371, the US trial registry maintained by the National Library of Medicine. NCT00085371 (mid enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.