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2026 data Public-data reference. official source

Recurrent Non-small Cell Lung Cancer

Open-data reference.

14 US clinical trials · 1 currently recruiting

Active & Recent Trials

RECRUITING NA 1,020 participants

Comprehensive Genomic Analysis in Tissue Samples From Patients With Recurrent or Stage IV Non-small Cell Lung Cancer

Barbara Ann Karmanos Cancer Institute

NCT02178163

ACTIVE NOT RECRUITING Phase 2 468 participants

A Study of Relatlimab Plus Nivolumab in Combination With Chemotherapy vs. Nivolumab in Combination With Chemotherapy as First Line Treatment for Participants With Stage IV or Recurrent Non-small Cell Lung Cancer (NSCLC)

Bristol-Myers Squibb

NCT04623775

ACTIVE NOT RECRUITING NA 29 participants

Image-Guided Hypofractionated Radiation Therapy With Stereotactic Body Radiation Therapy Boost and Combination Chemotherapy in Treating Patients With Stage II-III Non-Small Cell Lung Cancer That Cannot Be Removed By Surgery

Jonsson Comprehensive Cancer Center

NCT01345851

COMPLETED NA 129 participants

Erlotinib in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer

National Cancer Institute (NCI)

NCT00085280

COMPLETED Phase 2 80 participants

Erlotinib and Celecoxib in Treating Patients With Stage IIIB or Stage IV Recurrent Non-Small Cell Lung Cancer

National Cancer Institute (NCI)

NCT00062101

COMPLETED Phase 2 65 participants

S0341: Erlotinib in Treating Patients With Advanced Primary Non-Small Cell Lung Cancer

National Cancer Institute (NCI)

NCT00087412

COMPLETED Phase 2 60 participants

AZD2171 and Pemetrexed Disodium in Treating Patients With Relapsed Non-Small Cell Lung Cancer

National Cancer Institute (NCI)

NCT00410904

COMPLETED Phase 2 50 participants

CCI-779 in Treating Patients With Stage IIIB (With Pleural Effusion) or Stage IV Non-Small Cell Lung Cancer

National Cancer Institute (NCI)

NCT00079235

COMPLETED Phase 2 48 participants

A Phase II Trial of Triapine (NSC #663249) in Combination With Gemcitabine as Second Line Treatment of Non-Small Cell Lung Cancer

National Cancer Institute (NCI)

NCT00077350

COMPLETED Phase 2 42 participants

Bortezomib in Treating Patients With Stage IIIB or Stage IV Lung Cancer

National Cancer Institute (NCI)

NCT00118144

COMPLETED Phase 1 34 participants

Bortezomib Plus Gemcitabine and Carboplatin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer

National Cancer Institute (NCI)

NCT00052338

COMPLETED Phase 1 18 participants

Interleukin-12, Paclitaxel, and Trastuzumab in Treating Patients With Solid Tumors

National Cancer Institute (NCI)

NCT00028535

COMPLETED Phase 1 18 participants

Erlotinib Hydrochloride With or Without Cixutumumab in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer

National Cancer Institute (NCI)

NCT00778167

COMPLETED Early Phase 1 10 participants

Stereotactic Body Radiation Therapy After Surgery in Treating Patients With Stage III-IV Non-small Cell Lung Cancer

Roswell Park Cancer Institute

NCT01781741

Phase Distribution

PhaseTrial count
Early Phase 1 4
Phase 2 7

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Recurrent Non-small Cell Lung Cancer Trial Landscape

ClinicalTrials.gov lists 14 US studies indexed under Recurrent Non-small Cell Lung Cancer, and 1 of those are currently open to recruitment — roughly 7% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Recurrent Non-small Cell Lung Cancer shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 11 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Recurrent Non-small Cell Lung Cancer is led by National Cancer Institute (NCI) with 10 indexed trials, alongside 4 other organizations in the top contributor list. The list on this page surfaces up to 14 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Recurrent Non-small Cell Lung Cancer?

PlainTrial tracks 14 US clinical trials for Recurrent Non-small Cell Lung Cancer, of which 1 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Recurrent Non-small Cell Lung Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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