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NCT00331682 · ClinicalTrials.gov registry record · Phase 2

Docetaxel and Flavopiridol in Treating Patients With Refractory Metastatic Pancreatic Cancer

A Phase 2 study of Stage IV Pancreatic Cancer and Adenocarcinoma of the Pancreas, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 2
Development phase
10
Enrollment target
1
Study location

NCT00331682: Completed Phase 2 study of Stage IV Pancreatic Cancer and Adenocarcinoma of the Pancreas, sponsored by National Cancer Institute (NCI).

NCT00331682 is a Phase 2 study of Stage IV Pancreatic Cancer and Adenocarcinoma of the Pancreas that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 10 participants, below the 79-participant average among 15 other Stage IV Pancreatic Cancer trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00331682, a Phase 2 study of Stage IV Pancreatic Cancer and Adenocarcinoma of the Pancreas, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 2
Development phase
10 participants
Enrollment target
1
Study location

Study Summary

Drugs used in chemotherapy, such as docetaxel and flavopiridol, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. Flavopiridol may also help docetaxel work better by making tumor cells more sensitive to the drug. This phase II trial is studying how well giving docetaxel followed by flavopiridol works in treating patients with refractory metastatic pancreatic cancer.

Primary Outcome

Objective response rate as measured by RECIST criteria

Interventions

  • DRUG docetaxel
  • DRUG alvocidib

Study Locations (1)

New York

  • Memorial Sloan-Kettering Cancer Center - New York

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2006-03
Est. Completion 2008-05
Phase Phase 2
National Cancer Institute (NCI)

3,257 total trials

What the finished NCT00331682 record still lists

NCT00331682 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 79-participant average among 15 other Stage IV Pancreatic Cancer trials with a reported enrollment target (87% lower).

The record links to 3 conditions, with Stage IV Pancreatic Cancer appearing as the primary indexed condition, and to 2 interventions - of which docetaxel is the first listed.

NCT00331682 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT00331682 about?

NCT00331682 is a clinical study titled "Docetaxel and Flavopiridol in Treating Patients With Refractory Metastatic Pancreatic Cancer". Drugs used in chemotherapy, such as docetaxel and flavopiridol, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. Flavopiridol may also help docetaxe...

What is the current status of trial NCT00331682?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 10 participants. The study started on 2006-03. Estimated completion is 2008-05.

What conditions does trial NCT00331682 study?

This clinical trial studies the following conditions: Stage IV Pancreatic Cancer, Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer.

What interventions are being tested in trial NCT00331682?

The interventions under investigation include: docetaxel (DRUG), alvocidib (DRUG).

Who is sponsoring clinical trial NCT00331682?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00331682 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Stage IV Pancreatic Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00331682's enrollment target sits among peer trials

10 15th of 15 higher than 1 of 15 other Stage IV Pancreatic Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Stage IV Pancreatic Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00331682, the US trial registry maintained by the National Library of Medicine. NCT00331682 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.