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ClinicalTrials.gov 14 recruiting now full pipeline

Stage II Lung Cancer AJCC v8: full-pipeline trial registry

14 of 25 indexed Stage II Lung Cancer AJCC v8 trials are currently recruiting.

Corpus placement: #652 of 28,707 conditions by registered trial count.

25 US clinical trials · 14 currently recruiting · #652 of 28,707 conditions by registered trial count

Stage II Lung Cancer AJCC v8: 25 US clinical trials tracked, 14 recruiting.

Stage II Lung Cancer AJCC v8 is the subject of 25 registered US clinical trials on ClinicalTrials.gov, 14 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 7 of these trials.

Enrollment posture brief

Registry condition stage-ii-lung-cancer-ajcc-v8

OPEN 14 | RECR 56% | LATE 6 | EARLY 9 | RANK #652 | SPON 7

Nearest open-share peer: Celiac Disease (56% recruiting · 25 trials)

Stage II Lung Cancer AJC (th…56%Alpha-1 Antitrypsin Deficien48%Alcohol Use40%Acute Lymphocytic Leukemia36%Alcohol-Related Disorders36%
Open-enrollment share among volume-matched conditions near Stage II Lung Cancer AJCC v8

Stage II Lung Cancer AJCC v8 lists 14 open slots (56% of 25 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Stage II Lung Cancer AJCC v8 on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Stage II Lung Cancer AJCC v8 is recruiting above its size-band peers.

    14 of 25 indexed trials (56%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Stage II Lung Cancer AJCC v8 research.

    M.D. Anderson Cancer Center accounts for 7 of 25 trials (28%). 12 distinct sponsors appear on at least one study for this condition label.

  3. Typical Stage II Lung Cancer AJCC v8 enrolment sits around 98 participants.

    Median target enrolment is 98 among the 25 trials that report a genuine target (sentinel values excluded). 13 of those (52%) plan for fewer than 100 participants.

  4. Stage II Lung Cancer AJCC v8 research is mostly interventional.

    24 interventional and 1 observational studies make up this index (96% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 26Phase 36

Open and recent trials

25 total, page 1 of 1

RECRUITING Phase 3 1,210 participants

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

National Cancer Institute (NCI)

NCT04267848

RECRUITING Phase 3 1,100 participants

Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer

Alliance for Clinical Trials in Oncology

NCT06632327

RECRUITING NA 400 participants

Dyadic Yoga Intervention in Improving Physical Performance and Quality of Life in Patients With Stage I-IV Non-small Cell Lung or Esophageal Cancer Undergoing Radiotherapy and Their Caregivers

M.D. Anderson Cancer Center

NCT03948100

RECRUITING Phase 3 306 participants

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

National Cancer Institute (NCI)

NCT06498635

RECRUITING Phase 2 220 participants

Respiratory Muscle Training Before Surgery in Preventing Lung Complications in Patients With Stage I-IIIB Lung Cancer

Roswell Park Cancer Institute

NCT04067830

RECRUITING NA 150 participants

Quality of Life Intervention to Inform Patient Decision-Making in Early-Stage Lung Cancer

Roswell Park Cancer Institute

NCT05292521

RECRUITING NA 100 participants

The Impact of Surgical Technique on Circulating Tumor DNA in Stage I-III Non-Small Cell Lung Cancer

Thomas Jefferson University

NCT05502523

RECRUITING NA 100 participants

A Tool for Improving the Shared Decision-making Process in Patients With Non-small Cell Lung Cancer

Mayo Clinic

NCT06122064

RECRUITING NA 100 participants

New York Better Breathing Study

Roswell Park Cancer Institute

NCT06869447

RECRUITING NA 70 participants

Stereotactic Body Radiation Therapy Planning With Artificial Intelligence-Directed Dose Recommendation for Treatment of Primary or Metastatic Lung Tumors, RAD-AI Study

Northwestern University

NCT05802186

RECRUITING Phase 2 60 participants

Cemiplimab and Fianlimab Before Surgery for the Treatment of Stage IB-IIIB Non-Small Cell Lung Cancer

Mayo Clinic

NCT06918132

RECRUITING Phase 2 50 participants

Canakinumab for the Prevention of Lung Cancer, the Can-Prevent-Lung Trial

M.D. Anderson Cancer Center

NCT04789681

RECRUITING NA 34 participants

Adaptive Radiation Planning for the Reduction of Radiation-Induced Toxicity in Patients With Stage II-IV Non-small Cell Lung Cancer

Rutgers, The State University of New Jersey

NCT04751747

RECRUITING Phase 1 28 participants

Papaverine in Combination With Chemoradiation for the Treatment of Stage II-III Non-small Cell Lung Cancer

Ohio State University Comprehensive Cancer Center

NCT05136846

ACTIVE NOT RECRUITING Phase 3 544 participants

Testing the Addition of a New Immunotherapy Drug, Atezolizumab (MPDL3280A), to the Usual Chemoradiation (CRT) Therapy Treatment for Limited Stage Small Cell Lung Cancer (LS-SCLC)

National Cancer Institute (NCI)

NCT03811002

ACTIVE NOT RECRUITING Phase 3 480 participants

Testing the Addition of the Drug Atezolizumab to the Usual Radiation Treatment for Patients With Early Non-small Cell Lung Cancer

National Cancer Institute (NCI)

NCT04214262

ACTIVE NOT RECRUITING Phase 3 403 participants

Self-Management Survivorship Care in Stage I-III Non-small Cell Lung Cancer or Colorectal Cancer

City of Hope Medical Center

NCT04428905

ACTIVE NOT RECRUITING NA 98 participants

Decision Aid for the Improvement of Decision-Making in Patients With Non-small Cell Lung Cancer

OHSU Knight Cancer Institute

NCT04946279

ACTIVE NOT RECRUITING 74 participants

Microwave Ablation or Wedge Resection for the Treatment of Lung, Sarcoma and Colorectal Lesions, ALLUME Study

M.D. Anderson Cancer Center

NCT04430725

ACTIVE NOT RECRUITING NA 70 participants

Online Psychosocial Intervention in Improving Social Well-Being and Support in Women With Stage I-IV Non-small Cell Lung Cancer Undergoing Treatment

M.D. Anderson Cancer Center

NCT03731585

ACTIVE NOT RECRUITING Phase 2 47 participants

Study of Radiation Therapy Followed by Atezolizumab in Stage II or III Non-small Cell Lung Cancer Patients

National Cancer Institute (NCI)

NCT04310020

ACTIVE NOT RECRUITING Phase 2 45 participants

Pembrolizumab in Preventing Lung Cancer in Patients With Stage I-II Non-Small Cell Lung Cancer or High-Risk Pulmonary Nodules, the IMPRINT-Lung Study

M.D. Anderson Cancer Center

NCT03634241

ACTIVE NOT RECRUITING Phase 1 34 participants

NBTXR3 and Radiation Therapy for the Treatment of Inoperable Recurrent Non-small Cell Lung Cancer

M.D. Anderson Cancer Center

NCT04505267

ACTIVE NOT RECRUITING Phase 1 21 participants

Ipilimumab and Nivolumab in Combination With Radiation Therapy in Treating Patients With Stage 2-3 Non-small Lung Cancer

M.D. Anderson Cancer Center

NCT04013542

ACTIVE NOT RECRUITING Phase 2 5 participants

Subcutaneous Atezolizumab for the Treatment of Non-small Cell Lung Cancer

University of Southern California

NCT05340309

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 6
Phase 3 6

Named interventions

Most-linked intervention names on Stage II Lung Cancer AJCC v8 records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Questionnaire Administration Other
9 trials
Biospecimen Collection Procedure
9 trials
Computed Tomography Procedure
7 trials
Quality-of-Life Assessment Other
6 trials
Best Practice Other
4 trials
Carboplatin Drug
4 trials
Radiation Therapy Radiation
3 trials
Magnetic Resonance Imaging Procedure
3 trials

US sites by state

Facility locations filed on Stage II Lung Cancer AJCC v8 trials. A trial with sites in several states counts in each.

California 9 trials
Texas 7 trials
Arkansas 6 trials
New York 4 trials
Alaska 4 trials
Arizona 3 trials
Alabama 3 trials
Minnesota 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Stage II Lung Cancer AJCC v8 page

25 registered trials, 14 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stage II Lung Cancer AJCC v8 condition card totals 25 registered trials; most-linked intervention Questionnaire Administration; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.