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ClinicalTrials.gov 9 recruiting now official registry

Spina Bifida clinical trials

9 of 17 indexed Spina Bifida trials are currently recruiting.

17 US clinical trials · 9 currently recruiting

Spina Bifida is the subject of 17 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. The most active sponsor is Grand Valley State University, running 2 of these trials.

The research picture

Spina Bifida has 17 registered US clinical trials, 9 of them open to new participants right now, about 53% of the total.

9
recruiting participants now
53%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
2
top sponsor: Grand Valley State University

Active & Recent Trials

17 total, page 1 of 1

RECRUITING NA 160 participants

Mobile Health Self-Management and Support System for Chronic and Complex Health Conditions

University of Pittsburgh

NCT02592291

RECRUITING NA 110 participants

In-Utero Endoscopic Correction of Spina Bifida

University of Southern California

NCT04362592

RECRUITING NA 44 participants

Evaluating Long-term Use of a Pediatric Robotic Exoskeleton (P.REX/Agilik) to Improve Gait in Children With Movement Disorders

National Institutes of Health Clinical Center (CC)

NCT05726591

RECRUITING NA 30 participants

Transcutaneous Spinal Stimulation for Children and Youth With Spina Bifida

Mayo Clinic

NCT06918119

RECRUITING 25 participants

Fetoscopic Neural Tube Defect Repair

Oregon Health and Science University

NCT06946563

RECRUITING NA 15 participants

Autologous Human Umbilical Cord Tissue Patch for Postnatal Closure of Open Neural Tube Defects

The University of Texas Health Science Center, Houston

NCT06929572

RECRUITING NA 12 participants

Transcutaneous Tibial Nerve Stimulation (TTNS) Treatment in Spina Bifida Pediatric Patients With Neurogenic Bladder

University of Texas Southwestern Medical Center

NCT06025734

RECRUITING NA 12 participants

Laparotomy Versus Percutaneous Endoscopic Correction of Myelomeningocele

USFetus

NCT03856034

RECRUITING NA 12 participants

Impact of Standing Programs in Children With Spina Bifida: A Single Subject Design

University of St. Augustine for Health Sciences

NCT06419049

ACTIVE NOT RECRUITING 140 participants

Psychosocial Adjustment of Adolescents With Spina Bifida

Loyola University Chicago

NCT00891891

ACTIVE NOT RECRUITING NA 67 participants

Incontinence and Quality of Life in Children With Spina Bifida

Indiana University

NCT03410667

ACTIVE NOT RECRUITING NA 50 participants

Fetoscopic NEOX Cord 1K® Spina Bifida Repair

The University of Texas Health Science Center, Houston

NCT04243889

ACTIVE NOT RECRUITING NA 30 participants

Fetoscopic Repair of Isolated Fetal Spina Bifida

Johns Hopkins University

NCT03090633

ACTIVE NOT RECRUITING NA 4 participants

Grand Valley State University (GVSU) Skills on Wheels

Grand Valley State University

NCT05339932

ACTIVE NOT RECRUITING NA 4 participants

Pediatric Powered Wheelchair Standing Devices: An Exploratory Study

Grand Valley State University

NCT05117827

COMPLETED NA 108 participants

Movement-2-Music: Lakeshore Examination of Activity, Disability, and Exercise Response Study

University of Alabama at Birmingham

NCT03797378

COMPLETED NA 20 participants

A Wheelchair Propulsion Training Program

Washington University School of Medicine

NCT04009187

Reading the Spina Bifida Trial Landscape

17 indexed Spina Bifida studies · 9 recruiting (53%).

Phase mix: 0 late (III/IV) vs 0 early (I/II).

Top sponsor: Grand Valley State University (2 trials), 9 others listed. 17 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Spina Bifida?

PlainTrial tracks 17 US clinical trials for Spina Bifida, of which 9 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Spina Bifida?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.